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View Structure Prediction Details

Protein: gi|124126863, gi...
Organism: synthetic construct
Length: 222 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|124126863, gi....

Description E-value Query
Range		 Subject
Range
SODM_MACFA - Superoxide dismutase [Mn], mitochondrial OS=Macaca fascicularis GN=SOD2 PE=2 SV=3
 6.0E-91 [1..222] [1..222]
SOD2 - superoxide dismutase 2, mitochondrial
 7.0E-91 [1..222] [1..222]
SODM_HORSE - Superoxide dismutase [Mn], mitochondrial OS=Equus caballus GN=SOD2 PE=2 SV=1
 7.0E-91 [1..222] [1..222]
SODM_MOUSE - Superoxide dismutase [Mn], mitochondrial OS=Mus musculus GN=Sod2 PE=1 SV=3
gi|1037120 - gi|1037120|gb|AAB34899.1| manganese superoxide dismutase; MnSOD [Mus sp.]
 8.0E-91 [1..222] [1..222]
gi|30584207, gi|... - gi|61370092|gb|AAX43436.1| superoxide dismutase 2 mitochondrial [synthetic construct], gi|61370084|g...
 9.0E-91 [1..222] [1..222]
SODM_PONPY - Superoxide dismutase [Mn], mitochondrial OS=Pongo pygmaeus GN=SOD2 PE=2 SV=3
gi|197100007 - gi|197100007|ref|NP_001127035.1| superoxide dismutase 2, mitochondrial [Pongo abelii]
 9.0E-91 [1..222] [1..222]

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Predicted Domain #1
Region A:
Residues: [1-222] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSRAVCGTS RQLAPVLGYL GSRQKHSLPD LPYDYGALEP HINAQIMQLH HSKHHAAYVN  60
   61 NLNVTEEKYQ EALAKGDVTA QIALQPALKF NGGGHINHSI FWTNLSPNGG GEPKGELLEA 120
  121 IKRDFGSFDK FKEKLTAASV GVQGSGWGWL GFNKERGHLQ IAACPNQDPL QGTTGLIPLL 180
  181 GIDVWEHAYY LQYKNVRPDY LKAIWNVINW ENVTERYMAC KK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 84.69897
Match: 1n0jA
Description: Mn superoxide dismutase (MnSOD)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
superoxide dismutase activity 7.08472506566271 bayes_pls_golite062009
oxidoreductase activity, acting on superoxide radicals as acceptor 7.08472506566271 bayes_pls_golite062009
oxidoreductase activity 2.73079314406851 bayes_pls_golite062009
protein binding 1.36581969443298 bayes_pls_golite062009
binding 1.30562201415299 bayes_pls_golite062009
antioxidant activity 0.766723962166325 bayes_pls_golite062009
cation binding 0.485672227923388 bayes_pls_golite062009
metal ion binding 0.485672227923388 bayes_pls_golite062009
ion binding 0.480092270451566 bayes_pls_golite062009
catalytic activity 0.390489225704392 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle