YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: Lerp-PB
Organism: Drosophila melanogaster
Length: 887 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Lerp-PB.

Description E-value Query
Range
Subject
Range
Lerp-PA - The gene lysosomal enzyme receptor protein is referred to in FlyBase by the symbol Dmel\Lerp (CG3107...
784.0 [0..1] [887..1]

Back

Predicted Domain #1
Region A:
Residues: [1-491]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRCSLQKDCA APTQENFRQQ MRFPIVISLL LLLFCSGESV AADAANQLKF STTECKLKEP  60
   61 IYGSTFDFSG LHSDLAHVVK SMNIGGDQFE FNICGNLSRT CNGESNVAAC LKRQGKEYIL 120
  121 GRQHELFYNN GNMFLKYKSG AKCDNGTADK PNYQLHVMFS CDYTLDAQPM HVTPYANEVC 180
  181 SFYISYRTPL ACLSIPEGLQ SNSCRVGDTK SNGTFDLMPL SDSNYHTSNR QGAFFVINVC 240
  241 KPVLYGENSM CPAGSSVCLF DSKATNPKER FINFGNVQTH PVVEKGQLLL RHESPTPCAK 300
  301 NSSANYTSVI YFSCDKFIRN AHPEFAGLGA DSCTYQFNFA TPLACNDLKP CTAFTSTNEL 360
  361 LDLSSLSSKP ARTLLKDGKN YTIAVCAHAG APCQENGGAC YEQNSTTISL GNSNSQLRFN 420
  421 QTGSLYLLYE DGAECSTATG MRRWSTKIEF VCANNATKDN GASTAGGSDS LKIIEDSNCQ 480
  481 LLIQYQTPLA C

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.045757
Match: 1q25A
Description: Crystal structure of N-terminal 3 domains of CI-MPR
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [492-660]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 REPIRCKATT YVDHTNDGLG SSGDELIDLT PLISATDNYE ARVELPASME HLVPKTTKFF  60
   61 LNVCRPLVPK YQLGCAGGSA ACMAKVTAAG APEEERSMGF PLVSLTQRNR TFAELAYLKG 120
  121 DPCPTDNTSE LSTHILFNCN MRAGRGQPVL RSVEDCAYRF EWETNVFCP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.3
Match: 1keoA
Description: Cation-dependent mannose 6-phosphate receptor, extracytoplasmic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 1.28747861690557 bayes_pls_golite062009
binding 1.10138386107409 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [661-887]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PHECTFSADT CDLVHDELGR RFNFKSAPFT KDGKIEIDYN ATKMSVNICG AHRKAMTDYS  60
   61 QALVNIFFTH ESPNCGREGT MNVQIRLICS DQTESSSTIS SDQQCNLLYV QRTPSICEFL 120
  121 SLGATQQNFE SNGSTSSSTS SSSTSTTTST TTQASPAAIL GAILSVTFCV TCLGLLAFSP 180
  181 ARRQRIRRLF RRSNSAVRYS RVQSNEEANL LLEPNGEFTE SDDDMLL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.30103
Match: 1ck7A
Description: Gelatinase A (MMP-2); Gelatinase A (MMP-2), C-terminal domain; Gelatinase A; Gelatinase A (MMP-2) type II modules
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 0.873001869096005 bayes_pls_golite062009
binding 0.813983818243772 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle