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View Structure Prediction Details

Protein: gi|123995447, gi...
Organism: synthetic construct
Length: 239 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|123995447, gi....

Description E-value Query
Range		 Subject
Range
PSA_PYRAB - Proteasome subunit alpha OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=psmA PE=3 SV=1
PSMA_PYRAB - Proteasome subunit alpha OS=Pyrococcus abyssi GN=psmA PE=3 SV=1
 2.0E-64 [1..232] [1..234]
PSA_PYRFU - Proteasome subunit alpha OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) GN=p...
PSMA_PYRFU - Proteasome subunit alpha OS=Pyrococcus furiosus GN=psmA PE=3 SV=1
 1.0E-63 [1..232] [1..234]
PSA_PYRHO - Proteasome subunit alpha OS=Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC ...
PSMA_PYRHO - Proteasome subunit alpha OS=Pyrococcus horikoshii GN=psmA PE=3 SV=1
 2.0E-63 [1..232] [1..234]
PSA_THEK1 - Proteasome subunit alpha OS=Thermococcus sp. (strain JCM 11816 / KS-1) GN=psmA PE=3 SV=1
PSA_THEK1, PSMA_... - Proteasome subunit alpha OS=Thermococcus sp. (strain KS-1) GN=psmA PE=3 SV=1, Proteasome subunit alp...
gi|11265988 - pir||T43887 proteasome alpha chain [imported] - Thermococcus sp
 2.0E-62 [1..236] [1..238]
PSMA_PYRKO - Proteasome subunit alpha OS=Pyrococcus kodakaraensis GN=psmA PE=3 SV=1
PSA_THEKO - Proteasome subunit alpha OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) GN=ps...
 4.0E-62 [1..236] [1..238]
gi|109112866 - gi|109112866|ref|XP_001096870.1| PREDICTED: proteasome (prosome, macropain) subunit, beta type, 6 is...
 1.0E-60 [1..238] [1..238]
PSA4_SPIOL - Proteasome subunit alpha type-4 OS=Spinacia oleracea GN=PAC1 PE=2 SV=1
 2.0E-60 [6..235] [1..240]
gi|218186097 - gi|218186097|gb|EEC68524.1| hypothetical protein OsI_36813 [Oryza sativa Indica Group]
PSA5_ORYSJ - Proteasome subunit alpha type-5 OS=Oryza sativa subsp. japonica GN=PAE1 PE=2 SV=1
PSA5_ORYSA - Proteasome subunit alpha type 5 (EC 3.4.25.1) (20S proteasome alpha subunit E) (20S proteasome subun...
 5.0E-60 [3..236] [1..237]
PSB6_BOVIN - Proteasome subunit beta type-6 OS=Bos taurus GN=PSMB6 PE=1 SV=1
 5.0E-60 [1..238] [1..238]
gi|65304454 - gi|65304454|emb|CAI76833.1| proteasome subunit, putative [Theileria annulata]
gi|84997473 - gi|84997473|ref|XP_953458.1| proteasome subunit [Theileria annulata strain Ankara]
 1.0E-59 [6..233] [1..240]

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Predicted Domain #1
Region A:
Residues: [1-239] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAATLLAARG AGPAPAWGPE AFTPDWESRE VSTGTTIMAV QFDGGVVLGA DSRTTTGSYI  60
   61 ANRVTDKLTP IHDRIFCCRS GSAADTQAVA DAVTYQLGFH SIELNEPPLV HTAASLFKEM 120
  121 CYRYREDLMA GIIIAGWDPQ EGGQVYSVPM GGMMVRQSFA IGGSGSSYIY GYVDATYREG 180
  181 MTKEECLQFT ANALALAMER DGSSGGVIRL AAIAESGVER QVLLGDQIPK FAVATLPPA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.522879
Match: 1iruH
Description: Proteasome beta subunit (catalytic)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
endopeptidase activity 6.91642761177919 bayes_pls_golite062009
peptidase activity 6.84511694091156 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 6.5973571808298 bayes_pls_golite062009
hydrolase activity 4.47652590304822 bayes_pls_golite062009
threonine-type endopeptidase activity 2.98214579292788 bayes_pls_golite062009
threonine-type peptidase activity 2.98214579292788 bayes_pls_golite062009
catalytic activity 1.19663085909195 bayes_pls_golite062009
binding 1.18139971903068 bayes_pls_golite062009
nucleic acid binding 0.448212653390607 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle