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View Structure Prediction Details

Protein: gi|123994115, gi...
Organism: synthetic construct
Length: 445 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|123994115, gi....

Description E-value Query
Range
Subject
Range
gi|114629263 - gi|114629263|ref|XP_507638.2| PREDICTED: GDP dissociation inhibitor 2 [Pan troglodytes]
0.0 [1..445] [307..754]
gi|74150721 - gi|74150721|dbj|BAE25494.1| unnamed protein product [Mus musculus]
0.0 [1..445] [68..512]
gi|285975 - gi|285975|dbj|BAA03095.1| human rab GDI [Homo sapiens]
0.0 [1..445] [1..445]
gi|61372597, gi|... - gi|61372597|gb|AAX43872.1| GDP dissociation inhibitor 2 [synthetic construct], gi|30583991|gb|AAP362...
0.0 [1..445] [1..445]
gi|109088117 - gi|109088117|ref|XP_001105854.1| PREDICTED: GDP dissociation inhibitor 2 isoform 5 [Macaca mulatta]
0.0 [1..445] [1..445]
GDIB_RAT - Rab GDP dissociation inhibitor beta OS=Rattus norvegicus GN=Gdi2 PE=1 SV=2
GDIB_MOUSE - Rab GDP dissociation inhibitor beta OS=Mus musculus GN=Gdi2 PE=1 SV=1
0.0 [1..445] [1..445]
gi|3420726, gi|4... - gi|45384364|ref|NP_990335.1| GDP dissociation inhibitor 2 [Gallus gallus], gi|3420726|gb|AAC31910.1|...
0.0 [1..445] [1..445]

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Predicted Domain #1
Region A:
Residues: [1-445]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNEEYDVIVL GTGLTECILS GIMSVNGKKV LHMDRNPYYG GESASITPLE DLYKRFKIPG  60
   61 SPPESMGRGR DWNVDLIPKF LMANGQLVKM LLYTEVTRYL DFKVTEGSFV YKGGKIYKVP 120
  121 STEAEALASS LMGLFEKRRF RKFLVYVANF DEKDPRTFEG IDPKKTTMRD VYKKFDLGQD 180
  181 VIDFTGHALA LYRTDDYLDQ PCYETINRIK LYSESLARYG KSPYLYPLYG LGELPQGFAR 240
  241 LSAIYGGTYM LNKPIEEIIV QNGKVIGVKS EGEIARCKQL ICDPSYVKDR VEKVGQVIRV 300
  301 ICILSHPIKN TNDANSCQII IPQNQVNRKS DIYVCMISFA HNVAAQGKYI AIVSTTVETK 360
  361 EPEKEIRPAL ELLEPIEQKF VSISDLLVPK DLGTESQIFI SRTYDATTHF ETTCDDIKNI 420
  421 YKRMTGSEFD FEEMKRKKND IYGED

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 1lv0A
Description: Crystal structure of the Rab effector guanine nucleotide dissociation inhibitor (GDI) in complex with a geranylgeranyl (GG) peptide
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
small GTPase regulator activity 1.82777033221452 bayes_pls_golite062009
GTPase regulator activity 1.69589677829425 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 1.67690582043816 bayes_pls_golite062009
binding 1.28745887296004 bayes_pls_golite062009
enzyme regulator activity 1.00883251592654 bayes_pls_golite062009
amine oxidase activity 0.93095855430028 bayes_pls_golite062009
GDP-dissociation inhibitor activity 0.387378304822822 bayes_pls_golite062009
protein binding 0.347133050347128 bayes_pls_golite062009
transporter activity 0.0442116448779152 bayes_pls_golite062009
antioxidant activity 0.0209903577090486 bayes_pls_golite062009
transcription regulator activity 0.00424758775661527 bayes_pls_golite062009

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