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View Structure Prediction Details

Protein: gi|60655429, gi|...
Organism: synthetic construct
Length: 400 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|60655429, gi|....

Description E-value Query
Range
Subject
Range
gi|30584105, gi|... - gi|61372632|gb|AAX43880.1| mevalonate (diphospho) decarboxylase [synthetic construct], gi|30584105|g...
2.0E-97 [1..400] [1..400]
gi|73956933 - gi|73956933|ref|XP_546783.2| PREDICTED: similar to Diphosphomevalonate decarboxylase (Mevalonate pyr...
8.0E-95 [1..400] [1..400]
gi|109129490 - gi|109129490|ref|XP_001089404.1| PREDICTED: diphosphomevalonate decarboxylase [Macaca mulatta]
1.0E-94 [1..400] [1..401]
MVD1_BOVIN - Diphosphomevalonate decarboxylase OS=Bos taurus GN=MVD PE=2 SV=1
1.0E-93 [1..400] [1..400]
gi|51980639, gi|... - gi|51980639|gb|AAH81784.1| Mevalonate (diphospho) decarboxylase [Rattus norvegicus], gi|149038387|gb...
1.0E-93 [1..397] [1..398]
MVD1_MOUSE - Diphosphomevalonate decarboxylase OS=Mus musculus GN=Mvd PE=1 SV=2
5.0E-93 [1..397] [1..398]
gi|114664083 - gi|114664083|ref|XP_523460.2| PREDICTED: diphosphomevalonate decarboxylase isoform 4 [Pan troglodyte...
1.0E-92 [1..400] [1..400]

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Predicted Domain #1
Region A:
Residues: [1-400]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASEKPLAAV TCTAPVNIAV IKYWGKRDEE LVLPINSSLS VTLHQDQLKT TTTAVISKDF  60
   61 TEDRIWLNGR EEDVGQPRLQ ACLREIRCLA RKRRNSRDGD PLPSSLSCKV HVASVNNFPT 120
  121 AAGLASSAAG YACLAYTLAR VYGVESDLSE VARRGSGSAC RSLYGGFVEW QMGEQADGKD 180
  181 SIARQVAPES HWPELRVLIL VVSAEKKLTG STVGMRASVE TSPLLRFRAE SVVPARMAEM 240
  241 ARCIRERDFP SFAQLTMKDS NQFHATCLDT FPPISYLNAI SWRIIHLVHR FNAHHGDTKV 300
  301 AYTFDAGPNA VIFTLDDTVA EFVAAVWHGF PPGSNGDTFL KGLQVRPAPL SAELQAALAM 360
  361 EPTPGGVKYI IVTQVGPGPQ ILDDPCAHLL GPDGLPKPAA 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.30103
Match: 1fi4A
Description: Mevalonate 5-diphosphate decarboxylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
diphosphomevalonate decarboxylase activity 2.34245588421319 bayes_pls_golite062009
binding 1.48300512137561 bayes_pls_golite062009
catalytic activity 0.836142537655721 bayes_pls_golite062009
structural constituent of ribosome 0.66774567862554 bayes_pls_golite062009
carbohydrate kinase activity 0.49664490095304 bayes_pls_golite062009
structural molecule activity 0.40691892506083 bayes_pls_golite062009
nucleic acid binding 0.369771518688522 bayes_pls_golite062009
protein binding 0.214066724623027 bayes_pls_golite062009
transcription regulator activity 0.212099606954236 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle