YRC Public Data Repository - Protein Structure Prediction

Protein:	IMP4_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	289 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IMP4_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|37654250 - gi\|37654250\|gb\|AAQ96230.1\| LRRGT00017 [Rattus norvegicus]	312.0	[0..12]	[287..12]
IMP4_YARLI - U3 small nucleolar ribonucleoprotein protein IMP4 OS=Yarrowia lipolytica GN=IMP4 PE=3 SV=1 IMP4_YARLI - U3 small nucleolar ribonucleoprotein protein IMP4 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) G...	308.0	[0..1]	[285..1]
gi\|49069886, gi\|... - gi\|71006196\|ref\|XP_757764.1\| hypothetical protein UM01617.1 [Ustilago maydis 521], ref\|XP_399232.1\| ...	307.0	[0..1]	[285..1]
gi\|190409064 - gi\|190409064\|gb\|EDV12329.1\| U3 small nucleolar ribonucleoprotein protein IMP4 [Saccharomyces cerevis... IMP4_YEAST - U3 small nucleolar ribonucleoprotein protein IMP4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / ... gi\|207341687 - gi\|207341687\|gb\|EDZ69673.1\| YNL075Wp-like protein [Saccharomyces cerevisiae AWRI1631] IMP4 - Component of the SSU processome, which is required for pre-18S rRNA processing; interacts with Mpp10...	306.0	[0..1]	[285..1]
gi\|12850634, gi\|... - gi\|30519917\|ref\|NP_848716.1\| U3 snoRNP protein 4 homolog [Mus musculus], gi\|12850634\|dbj\|BAB28797.1\|...	305.0	[0..12]	[287..12]
IMP4_CANGA - U3 small nucleolar ribonucleoprotein protein IMP4 OS=Candida glabrata (strain ATCC 2001 / CBS 138 / ... IMP4_CANGA - U3 small nucleolar ribonucleoprotein protein IMP4 OS=Candida glabrata GN=IMP4 PE=3 SV=1	304.0	[0..1]	[285..1]
gi\|66514411 - gi\|66514411\|ref\|XP_395323.2\| PREDICTED: similar to IMP4, U3 small nucleolar ribonucleoprotein, homol...	303.0	[0..1]	[289..1]
IMP4_ASHGO - U3 small nucleolar ribonucleoprotein protein IMP4 OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51... IMP4_ASHGO - U3 small nucleolar ribonucleoprotein protein IMP4 OS=Ashbya gossypii GN=IMP4 PE=3 SV=1	302.0	[0..1]	[285..1]

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Predicted Domain #1

Region A:
Residues: [1-63]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRRAVRERR QFIYKRNQEL QEAKLNEKRR ALRKALEGNK ELNKDLQEDS QLQKDYKYDE  60
   61 SRA

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [64-174]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQEETETNLD DEYHRLGERE PKVLVTTSRE PSSRLAQFAK EVRLLIPNSY RLNRGNIVVG  60
   61 SLVEAARAND ITDIVILHEH RGIPDGLVIS HLPYGPTLSF SLHNVVLRHD I

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	16.154902
Match:	2cxhA
Description:	Crystal structure of probable ribosomal biogenesis protein from Aeropyrum pernix K1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
aminoacyl-tRNA ligase activity	3.58650371779212	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	3.58624422951947	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	3.58624422951947	bayes_pls_golite062009
ligase activity	2.71574082295198	bayes_pls_golite062009
proline-tRNA ligase activity	2.35871952544841	bayes_pls_golite062009
binding	1.73857064375258	bayes_pls_golite062009
catalytic activity	0.902495165806215	bayes_pls_golite062009
protein binding	0.358563180490135	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [175-289]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNTGTMSEAY PHLIFENLTS KLGKRVKTAL SALFPPDPKD TTPRVVTFAN TDDYISFRHH  60
   61 IYAKTGPKQI ILSEAGPRFE MKLFEITLGT VDMVDADVEW KLKPYQRHKR DVLAE

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.74
Match:	1w94A
Description:	Crystal Structure of Mil (Mth680), an archaeal Imp4-like protein
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: