YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|188493155, gi...
Organism:	Escherichia coli 53638
Length:	502 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|188493155, gi....

Description	E-value	Query Range	Subject Range
GLPK2_THEMA, GLK... - Glycerol kinase 2 OS=Thermotoga maritima GN=glpK2 PE=3 SV=2, (Q9X1E4) Glycerol kinase 2 (EC 2.7.1.30... GLPK2_THEMA - Glycerol kinase 2 OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) GN=glpK2 ...	602.0	[0..5]	[499..2]
GLPK_CARHZ - Glycerol kinase OS=Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901) GN=gl...	595.0	[0..2]	[501..1]
gi\|254479176, gi... - gi\|254479176\|ref\|ZP_05092524.1\| glycerol kinase [Carboxydibrachium pacificum DSM 12653], gi\|22348899... GLPK_CALS4 - Glycerol kinase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 ... GLPK_THETN - Glycerol kinase OS=Thermoanaerobacter tengcongensis GN=glpK PE=3 SV=1	590.0	[0..5]	[500..3]
gi\|91075041, gi\|... - gi\|91213467\|ref\|YP_543453.1\| glycerol kinase [Escherichia coli UTI89], gi\|91075041\|gb\|ABE09922.1\| gl...	588.0	[0..1]	[502..36]
gi\|26111123, gi\|... - gi\|26250692\|ref\|NP_756732.1\| glycerol kinase [Escherichia coli CFT073], gi\|26111123\|gb\|AAN83306.1\|AE...	587.0	[0..1]	[502..36]
gi\|209752298, gi... - gi\|25287510\|pir\|\|C86082 glycerol kinase [imported] - Escherichia coli (strain O157:H7, substrain EDL... gi\|209914665, gi... - gi\|209921406\|ref\|YP_002295490.1\| glycerol kinase [Escherichia coli SE11], gi\|209914665\|dbj\|BAG79739.... gi\|15804515, gi\|... - gi\|15804515\|ref\|NP_290555.1\| glycerol kinase [Escherichia coli O157:H7 EDL933], gi\|12518827\|gb\|AAG59... gi\|115515317, gi... - gi\|117626193\|ref\|YP_859516.1\| glycerol kinase [Escherichia coli APEC O1], gi\|115515317\|gb\|ABJ03392.1...	585.0	[0..1]	[502..8]
GLPK_SHIB3 - Glycerol kinase OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=glpK PE=3 SV=1	585.0	[0..1]	[502..1]
gi\|193068070, gi... - gi\|75238369\|ref\|ZP_00722368.1\| COG0554: Glycerol kinase [Escherichia coli E110019], gi\|193068070\|ref...	585.0	[0..1]	[502..1]
GLPK_SHIDS - Glycerol kinase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=glpK PE=3 SV=1	584.0	[0..1]	[502..1]
gi\|7434247 - gi\|7434247\|pir\|\|C72254 glycerol kinase - Thermotoga maritima (strain MSB8) gi\|15644181, gi\|... - gi\|4981995\|gb\|AAD36500.1\|AE001795_3 glycerol kinase [Thermotoga maritima MSB8], gi\|15644181\|ref\|NP_2...	584.0	[0..5]	[486..2]

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Predicted Domain #1

Region A:
Residues: [1-502]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTEKKYIVAL DQGTTSSRAV VMDHDANIIS VSQREFEQIY PKPGWVEHDP MEIWATQSST  60
   61 LVEVLAKADI SSDQIAAIGI TNQRETTIVW EKETGKPIYN AIVWQCRRTA EICEHLKRDG 120
  121 LEDYIRSNTG LVIDPYFSGT KVKWILDHVE GSRERARRGE LLFGTVDTWL IWKMTQGRVH 180
  181 VTDYTNASRT MLFNIHTLDW DDKMLEVLDI PREMLPEVRR SSEVYGQTNI GGKGGTRIPI 240
  241 SGIAGDQQAA LFGQLCVKEG MAKNTYGTGC FMLMNTGEKA VKSENGLLTT IACGPTGEVN 300
  301 YALEGAVFMA GASIQWLRDE MKLINDAYDS EYFATKVQNT NGVYVVPAFT GLGAPYWDPY 360
  361 ARGAIFGLTR GVNANHIIRA TLESIAYQTR DVLEAMQADS GIRLHALRVD GGAVANNFLM 420
  421 QFQSDILGTR VERPEVREVT ALGAAYLAGL AVGFWQNLDE LQEKAVIERE FRPGIETTER 480
  481 NYRYAGWKKA VKRAMAWEEH DE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	166.0
Match:	1bo5O
Description:	Glycerol kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glycerol kinase activity	5.25911418019759	bayes_pls_golite062009
carbohydrate kinase activity	2.33338276303563	bayes_pls_golite062009
binding	1.92007657015464	bayes_pls_golite062009
hexokinase activity	1.70516840340504	bayes_pls_golite062009
glucose binding	1.58717365638543	bayes_pls_golite062009
protein binding	0.856838411407636	bayes_pls_golite062009
glucokinase activity	0.47468456642723	bayes_pls_golite062009
kinase activity	0.460541310603011	bayes_pls_golite062009
sugar binding	0.44352406324938	bayes_pls_golite062009
nucleic acid binding	0.413093555819235	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.381597272143844	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.324655711623803	bayes_pls_golite062009
catalytic activity	0.296484721581333	bayes_pls_golite062009
transcription regulator activity	0.285445761922116	bayes_pls_golite062009
DNA binding	0.279711618446837	bayes_pls_golite062009
monosaccharide binding	0.20435276425198	bayes_pls_golite062009
hydrolase activity	0.13181840194556	bayes_pls_golite062009
transferase activity	0.105619024604158	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: