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View Structure Prediction Details

Protein: gi|113194676, gi...
Organism: Drosophila melanogaster
Length: 418 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|113194676, gi....

Description E-value Query
Range
Subject
Range
gi|76627836 - gi|76627836|ref|XP_883615.1| PREDICTED: similar to neural precursor cell expressed, developmentally ...
258.0 [0..63] [407..155]

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Predicted Domain #1
Region A:
Residues: [1-197]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCACLIAKII LCSFRLYTIS AFYMLTTMSA SSNTNSLIEK EIDDEDMLSP IKSNNLVVRV  60
   61 NQDTDDNLQA LFDSVLNPGD AKRPLQLPLR MRKLPNSFFT PPAPSHSRAN SADSTYDAGS 120
  121 QSSINIGNKA SIVQQPDGQS PIAAIPQLQI QPSPQHSRLA IHHSRARSSP ASLQQNYNVR 180
  181 ARSDAAAANN PNANPSS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [198-330]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQQPAGPTFP ENSAQEFPSG APASSAIDLD AMNTCMSQDI PMSMQTVHKK QRSYDVISPI  60
   61 QLNRQLGALP PGWEQAKTND GQIYYLNHTT KSTQWEDPRI QYRQQQQILM AERIKQNDVL 120
  121 QTTKQTTTST IAN

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.41
Match: 1o6wA
Description: Splicing factor prp40
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.22107891661937 bayes_pls_golite062009
transcription regulator activity 1.15713675708979 bayes_pls_golite062009
protein binding 0.651765243224234 bayes_pls_golite062009
catalytic activity 0.601784505590861 bayes_pls_golite062009
transcription activator activity 0.0452587090203611 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [331-418]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLGPLPDGWE QAVTESGDLY FINHIDRTTS WNDPRMQSGL SVLDCPDNLV SSLQIEDNLC  60
   61 SNLFNDAQAI VNPPSSHKPD DLEWYKIN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.522879
Match: 1tk7A
Description: NMR structure of WW domains (WW3-4) from Suppressor of Deltex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.28256682962994 bayes_pls_golite062009
transcription regulator activity 1.24334238369909 bayes_pls_golite062009
protein binding 0.750551821210286 bayes_pls_golite062009
catalytic activity 0.581152441703125 bayes_pls_golite062009
transcription activator activity 0.27562799136895 bayes_pls_golite062009
transcription factor binding 0.21378499004769 bayes_pls_golite062009
transcription cofactor activity 0.10815300336376 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle