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View Structure Prediction Details

Protein: seq-PA
Organism: Drosophila melanogaster
Length: 882 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for seq-PA.

Description E-value Query
Range
Subject
Range
gi|68436397 - gi|68436397|ref|XP_688942.1| PREDICTED: similar to zinc finger protein 420 [Danio rerio]
507.0 [0..59] [607..423]

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Predicted Domain #1
Region A:
Residues: [1-212]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQQSRKFEGK IPKLSQTSAA TGGATAAAEA STSKSSQGQQ QQIVYVNMLP AANTLNGIPQ  60
   61 QQQQQQYAST DGNVYQLQNE ILCDANGHAV TAATASYQTT ASSPQQQQQQ QQQQQNVATS 120
  121 VADNVVTTIS SSSILHTNAN TNGVDTLAAT QQQQQQQQQQ QQQQQQQHYH YITTTGEDGQ 180
  181 TPTTIVFENY NGGMPAVSSA APTPVPVSQA NA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [213-348]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PATTTTTALV NTDGTIIEFD GSTYEEYHVL KSEPGSSDCL SNGSSAVAAD IIKYDPQHGV  60
   61 VGDEEDDDEN GMLHVKYEEQ SLEHDPENEH DAEQEHEYEE YQVIKAEVEA EAAELAAGTT 120
  121 SYTISQEQTG SGNTVL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [349-447]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSMVPKSGSA AAAKQKRKRK TRVIADDEQG EYLEKMSVRG LDIARYEHII DGVAYCLVCA  60
   61 KNDIFKTFKN KYSFQRHAYL FHEGQNRKIF ACPICNKEF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.522879
Match: 2dlqA
Description: No description for 2dlqA was found.

Predicted functions:

Term Confidence Notes
binding 3.10743787485868 bayes_pls_golite062009
transcription regulator activity 2.9286072149962 bayes_pls_golite062009
DNA binding 2.91902554182176 bayes_pls_golite062009
nucleic acid binding 2.84809232393523 bayes_pls_golite062009
transcription factor activity 2.01262882344347 bayes_pls_golite062009
transcription repressor activity 1.81101516804605 bayes_pls_golite062009
chromatin binding 1.30226466791538 bayes_pls_golite062009
transcription factor binding 1.1783268121342 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.11260773303318 bayes_pls_golite062009
transcription activator activity 1.10770079514261 bayes_pls_golite062009
protein binding 1.00484935878505 bayes_pls_golite062009
sequence-specific DNA binding 0.42806308573128 bayes_pls_golite062009
transcription corepressor activity 0.18282984873138 bayes_pls_golite062009
structure-specific DNA binding 0.0300220090535304 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [448-602]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRPDKMKMHK KDKHGDVPMP PSATTTPLKA DGPPAKRART ARTPRVRKTK DGSTPTKKRL  60
   61 AQIDSVLDDV QNGESLTMAP VSVSHSQQQQ QQQIQHSITT LAPSTPSQPQ HQLQTLPSLD 120
  121 FSGMILPGGA QLALANPGAT SSVGLQRGPA TPNGQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.69897
Match: 2i13A
Description: No description for 2i13A was found.

Predicted Domain #5
Region A:
Residues: [603-808]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAPPTTTLIY SNQLELQQAL LQQQLQGQSI MIQDQAGNLV PLQLDGTQAI YTTAPQAQRQ  60
   61 QTTATYQTTQ QQQQQPAQQP AGQAQQQPHY ELDNVTYLSS TAAATPTSAE QQQQQQQQQH 120
  121 VIGTVQSYQI LTPDGLQNFQ PKLETAELGD LCPYSQYTFT THAGAQPTLN ANALDAQTQH 180
  181 QQHHQQQQHH HQQQQHHQQT QLLQQQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [809-882]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PFATHHNPHQ QFMELKNELL IKGGDAYTLD TASMYHLPFS PTSMINAVND VNTSSLLETK  60
   61 EISYDISEAV LLAL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle