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View Structure Prediction Details

Protein: dab-1
Organism: Caenorhabditis elegans
Length: 492 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dab-1.

Description E-value Query
Range
Subject
Range
gi|25354045 - gi|25354045|pir||A88230 protein M110.5 [imported] - Caenorhabditis elegans
309.0 [0..1] [492..57]

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Predicted Domain #1
Region A:
Residues: [1-218]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQKSDISVE TANATSGKPN PPSPKSRLAM LKRTKKASNA SSDPFRFQNN GISYKGKLIG  60
   61 EQDVDKARGD AMCAEAMRTA KSIIKAAGAH KTRITLQINI DGIKVLDEKS GAVLHNFPVS 120
  121 RISFIARDSS DARAFGLVYG EPGGKYKFYG IKTAQAADQA VLAIRDMFQV VFEMKKKQIE 180
  181 QVKQQQIQDG GAEISSKKEG GVAVADLLDL ESELQQIE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.154902
Match: 1oqnA
Description: Crystal structure of the phosphotyrosine binding domain (PTB) of mouse Disabled 1 (Dab1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.75270183218429 bayes_pls_golite062009
protein binding 1.30337811957526 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [219-414]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RGVQQLSTVP TNCDAFGASP FGDPFVDSFN STATSNGTAN MSGTQVPFGG LQLPQVQQMQ  60
   61 MPMVQIPQQS HQNWPTSGAG SFDAWGQQQQ QQQMHHAHST PAFGTNGFSD TNPFASAFNT 120
  121 QARPPPLPTV APTQYRDPFS VHSSAIPNSN IDWTGTGTTK ENMAPSTNIQ QQQSSLHHAS 180
  181 TFANFGDNKF RAETWS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [415-492]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKKVTSLEEA FTKLVDMDAL VGGQGIKETK KNPFEHILNP PKASLNSMST TCSAAQMAAT  60
   61 QQHTTSSHAD PFGDDFFR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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