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View Structure Prediction Details

Protein: unc-42
Organism: Caenorhabditis elegans
Length: 264 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-42.

Description E-value Query
Range
Subject
Range
gi|786328 - gi|786328|gb|AAB32671.1| Pax-6 [Rattus sp.]
gi|480038, gi|446399 - gi|480038|pir||S36166 paired box transcription factor Pax-6 - rat (fragment), gi|446399|prf||1911405...
119.0 [0..35] [172..67]

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Predicted Domain #1
Region A:
Residues: [1-149]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDNLLNGAN GASTVSQFQE KVKDLGVSLH DFTAYYPSSL DTVSASLRPI SDPSSDGAFK  60
   61 KIKTEGLGGS VFGSSIAGVT NTPARRRHRT TFTQEQLQEL DAAFQKSHYP DIYVREELAR 120
  121 ITKLNEARIQ VWFQNRRAKH RKHEKQLNK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.39794
Match: 1fjlA
Description: Paired protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.57523737355937 bayes_pls_golite062009
DNA binding 3.00143272905695 bayes_pls_golite062009
nucleic acid binding 2.89825020286436 bayes_pls_golite062009
transcription factor activity 2.53664874743748 bayes_pls_golite062009
binding 1.68817361068715 bayes_pls_golite062009
sequence-specific DNA binding 1.56629498736977 bayes_pls_golite062009
transcription activator activity 1.26247803652791 bayes_pls_golite062009
protein binding 1.16239587634422 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.14821760889085 bayes_pls_golite062009
transcription repressor activity 0.20862059645422 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [150-264]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AINPPHSFLS NPANTLMRQG MYPAALNRDG FWYQSYQRPM PYPTASPSYS NSFTNPIANF  60
   61 GHSITSFQAD DEFYQKSLAL RMTTTPSAAT AATSLANINY QQTQPSEAST NPPSI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle