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View Structure Prediction Details

Protein: CE39515
Organism: Caenorhabditis elegans
Length: 640 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE39515.

Description E-value Query
Range
Subject
Range
gi|50731574 - gi|50731574|ref|XP_418283.1| PREDICTED: similar to guanine nucleotide exchange factor [Gallus gallus...
389.0 [0..30] [640..875]

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Predicted Domain #1
Region A:
Residues: [1-184]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRETKEWRGT TSTSRVFVQK GYQLSDELAL RKVQVLERRY GGMQLAHRAA TVIQRAWREY  60
   61 CIMKQWMVIR HKHDTIPDHL DARCGVSNSQ RNELSLTSRY ATSLSAQLRI DRAARSTTLD 120
  121 RSPPSPAPPV LVNLQNSNMI DSLMSPRLGN RRFGAAASRC APAAAELTST EVWLPRPSLV 180
  181 NHNP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [185-447]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AHSNSLPRLD KHRVHERSES SNGRKKSEVK PPRQMTDQER KRQYRIALNF FNKKPERGVQ  60
   61 LLTAWGFVKN SPDSLASLLF GRRGLSKSMI GEYIGTLHSP YHSLVLKYFT ALIDIRGLEV 120
  121 DVALRKAMQF FILPKEAEKI DRIIQAFALH YSKSNPKRTS HYRGGWDTIH LLSFAIIMLN 180
  181 TDLHSPNVKQ RMTQADFVKN LRGQDKISGE KNGEDIDRKT LEGIYDRIKK DELKAGDDHV 240
  241 AQVQRVDRAI VGKDKPRLTE TPR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.522879
Match: 1r8mE
Description: SEC7 DOMAIN OF THE ARF EXCHANGE FACTOR ARNO WITH BREFELDIN A-SENSITIZING MUTATIONS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
enzyme regulator activity 0.33175950121636 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 0.31803821430449 bayes_pls_golite062009
GTPase regulator activity 0.31764113391724 bayes_pls_golite062009
guanyl-nucleotide exchange factor activity 0.19174216196088 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [448-640]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLVCYCRLQQ VSDPTKRQSS SARERDVFLF NDMIVVAKGV RRGSTSMAGC TYTLKQWTLL  60
   61 LGAHVTEFQR GQYEFGLTIT CPNKDKIHFN ARNFEDRCHF VADVTESIRE ATEMEQVRLE 120
  121 MEMEQHTTTT IRPDNQRDSG LPDMDESMKL SNGSNSSAGS SNSSTNGVNN SSFRRLSFNS 180
  181 LDSGVVEEHL DAC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.221849
Match: 1fhwA
Description: Grp1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.597587183571285 bayes_pls_golite062009
protein binding 0.29116370406325 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle