YRC Public Data Repository - Protein Structure Prediction

Protein:	IPYR_ECOLI
Organism:	Escherichia coli
Length:	176 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IPYR_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|67157940, gi\|... - gi\|67157940\|ref\|ZP_00419085.1\| Inorganic diphosphatase [Azotobacter vinelandii AvOP], gi\|67085209\|gb... gi\|67157940 - gi\|67157940\|ref\|ZP_00419085.1\| Inorganic diphosphatase [Azotobacter vinelandii AvOP]	283.0	[0..1]	[175..330]
gi\|83631974, gi\|... - gi\|83643931\|ref\|YP_432366.1\| inorganic pyrophosphatase [Hahella chejuensis KCTC 2396], gi\|83631974\|g...	268.0	[0..1]	[174..1]
gi\|115515697, gi... - gi\|117626573\|ref\|YP_859896.1\| inorganic pyrophosphatase [Escherichia coli APEC O1], gi\|115515697\|gb\|... gi\|170021762, gi... - gi\|170021762\|ref\|YP_001726716.1\| inorganic pyrophosphatase [Escherichia coli ATCC 8739], gi\|16975669... gi\|124500731, gi... - gi\|124528289\|ref\|ZP_01699613.1\| Inorganic diphosphatase [Escherichia coli B], gi\|124500731\|gb\|EAY482... gi\|218692615, gi... - gi\|218692615\|ref\|YP_002400827.1\| inorganic pyrophosphatase [Escherichia coli ED1a], gi\|218430179\|emb... gi\|218368156, gi... - gi\|218561387\|ref\|YP_002394300.1\| inorganic pyrophosphatase [Escherichia coli S88], gi\|218368156\|emb\|... gi\|218434933, gi... - gi\|218707836\|ref\|YP_002415355.1\| inorganic pyrophosphatase [Escherichia coli UMN026], gi\|218434933\|e... gi\|218697977, gi... - gi\|218697977\|ref\|YP_002405644.1\| inorganic pyrophosphatase [Escherichia coli 55989], gi\|218354709\|em... IPYR_ECOL6 - Inorganic pyrophosphatase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=ppa PE=3... gi\|75515464, gi\|... - gi\|75515464\|ref\|ZP_00737621.1\| COG0221: Inorganic pyrophosphatase [Escherichia coli 53638], gi\|18849... gi\|110644588, gi... - gi\|110644588\|ref\|YP_672318.1\| inorganic pyrophosphatase [Escherichia coli 536], gi\|110346180\|gb\|ABG7... gi\|193063638, gi... - gi\|75258329\|ref\|ZP_00729760.1\| COG0221: Inorganic pyrophosphatase [Escherichia coli E22], gi\|1930636... gi\|91075354, gi\|... - gi\|91213780\|ref\|YP_543766.1\| inorganic pyrophosphatase [Escherichia coli UTI89], gi\|91075354\|gb\|ABE1... gi\|191170839, gi... - gi\|75242385\|ref\|ZP_00726147.1\| COG0221: Inorganic pyrophosphatase [Escherichia coli F11], gi\|1911708... gi\|75235466, gi\|... - gi\|75235466\|ref\|ZP_00719674.1\| COG0221: Inorganic pyrophosphatase [Escherichia coli E110019], gi\|193... IPYR_ECOL6 - Inorganic pyrophosphatase OS=Escherichia coli O6 GN=ppa PE=3 SV=3 gi\|75229598, gi\|... - gi\|75229598\|ref\|ZP_00716137.1\| COG0221: Inorganic pyrophosphatase [Escherichia coli B7A], gi\|1911672... gi\|194426577, gi... - gi\|75212218\|ref\|ZP_00712258.1\| COG0221: Inorganic pyrophosphatase [Escherichia coli B171], gi\|194426... gi\|157079818, gi... - gi\|75188940\|ref\|ZP_00702207.1\| COG0221: Inorganic pyrophosphatase [Escherichia coli E24377A], gi\|157... gi\|83586744, gi\|... - gi\|83586744\|ref\|ZP_00925376.1\| COG0221: Inorganic pyrophosphatase [Escherichia coli 101-1], gi\|19443... gi\|194417876, gi... - gi\|83569401\|ref\|ZP_00920855.1\| COG0221: Inorganic pyrophosphatase [Shigella dysenteriae 1012], gi\|19... gi\|227836295, gi... - gi\|227886722\|ref\|ZP_04004527.1\| inorganic pyrophosphatase [Escherichia coli 83972], gi\|227836295\|gb\|... gi\|226901812, gi... - gi\|237703900\|ref\|ZP_04534381.1\| inorganic pyrophosphatase [Escherichia sp. 3_2_53FAA], gi\|226901812\|... gi\|251787476, gi... - gi\|251787476\|ref\|YP_003001780.1\| hypothetical protein B21_04059 [Escherichia coli BL21], gi\|24237974... gi\|254290905, gi... - gi\|254290905\|ref\|YP_003056655.1\| inorganic pyrophosphatase [Escherichia coli BL21(DE3)], gi\|25398021... gi\|254037246, gi... - gi\|254037246\|ref\|ZP_04871323.1\| inorganic pyrophosphatase [Escherichia sp. 1_1_43], gi\|226840352\|gb\|... gi\|254164155, gi... - gi\|254164155\|ref\|YP_003047265.1\| inorganic pyrophosphatase [Escherichia coli B str. REL606], gi\|2539...	267.0	[0..1]	[176..1]
gi\|109896471, gi... - gi\|76792190\|ref\|ZP_00774692.1\| Inorganic diphosphatase [Pseudoalteromonas atlantica T6c], gi\|7659262...	265.0	[0..1]	[176..1]
gi\|77973992, gi\|... - gi\|77973992\|ref\|ZP_00829535.1\| COG0221: Inorganic pyrophosphatase [Yersinia frederiksenii ATCC 33641... gi\|162421500, gi... - gi\|77634763\|ref\|ZP_00796857.1\| COG0221: Inorganic pyrophosphatase [Yersinia pestis Angola], gi\|16242... gi\|117675055, gi... - gi\|77631453\|ref\|ZP_00794039.1\| COG0221: Inorganic pyrophosphatase [Yersinia pseudotuberculosis IP 31... gi\|165937420, gi... - gi\|89104090\|ref\|ZP_01176644.1\| COG0221: Inorganic pyrophosphatase [Yersinia pestis biovar Orientalis... gi\|108806069, gi... - gi\|108806069\|ref\|YP_649985.1\| inorganic pyrophosphatase [Yersinia pestis Antiqua], gi\|108777982\|gb\|A... gi\|149288935, gi... - gi\|153997298\|ref\|ZP_02022398.1\| inorganic pyrophosphatase [Yersinia pestis CA88-4125], gi\|149288935\|... Q66F85\|Q66F85_YERPS - Inorganic pyrophosphatase - Yersinia pseudotuberculosis gi\|145212513, gi... - gi\|145600817\|ref\|YP_001164893.1\| inorganic pyrophosphatase [Yersinia pestis Pestoides F], gi\|1452125... gi\|108777073, gi... - gi\|229903901\|ref\|ZP_04519014.1\| inorganic pyrophosphatase [Yersinia pestis Nepal516], gi\|229679671\|g... gi\|166961475, gi... - gi\|167420669\|ref\|ZP_02312422.1\| inorganic pyrophosphatase [Yersinia pestis biovar Orientalis str. MG... gi\|167401256, gi... - gi\|167401256\|ref\|ZP_02306756.1\| inorganic pyrophosphatase [Yersinia pestis biovar Antiqua str. UG05-... gi\|167469959 - gi\|167469959\|ref\|ZP_02334663.1\| inorganic pyrophosphatase [Yersinia pestis FV-1] gi\|167423772, gi... - gi\|167423772\|ref\|ZP_02315525.1\| inorganic pyrophosphatase [Yersinia pestis biovar Mediaevalis str. K... gi\|186893816, gi... - gi\|186893816\|ref\|YP_001870928.1\| inorganic pyrophosphatase [Yersinia pseudotuberculosis PB1/+], gi\|1... gi\|170025982, gi... - gi\|170025982\|ref\|YP_001722487.1\| inorganic pyrophosphatase [Yersinia pseudotuberculosis YPIII], gi\|1... gi\|229695541, gi... - gi\|229839175\|ref\|ZP_04459334.1\| inorganic pyrophosphatase [Yersinia pestis biovar Orientalis str. PE... gi\|229700442, gi... - gi\|229896664\|ref\|ZP_04511831.1\| inorganic pyrophosphatase [Yersinia pestis Pestoides A], gi\|22970044... gi\|229687231, gi... - gi\|229899739\|ref\|ZP_04514880.1\| inorganic pyrophosphatase [Yersinia pestis biovar Orientalis str. In... gi\|122087750, gi... - gi\|123440789\|ref\|YP_001004780.1\| inorganic pyrophosphatase [Yersinia enterocolitica subsp. enterocol... gi\|165928155, gi... - gi\|165928155\|ref\|ZP_02223987.1\| inorganic pyrophosphatase [Yersinia pestis biovar Orientalis str. F1... gi\|166204794, gi... - gi\|166213999\|ref\|ZP_02240034.1\| inorganic pyrophosphatase [Yersinia pestis biovar Antiqua str. B4200... gi\|165989700, gi... - gi\|166011316\|ref\|ZP_02232214.1\| inorganic pyrophosphatase [Yersinia pestis biovar Antiqua str. E1979... gi\|22124577, gi\|... - gi\|22124577\|ref\|NP_668000.1\| inorganic pyrophosphatase [Yersinia pestis KIM], gi\|21957379\|gb\|AAM8425... gi\|51594807, gi\|... - gi\|51594807\|ref\|YP_068998.1\| inorganic pyrophosphatase [Yersinia pseudotuberculosis IP 32953], gi\|51... gi\|45435273, gi\|... - gi\|45440416\|ref\|NP_991955.1\| inorganic pyrophosphatase [Yersinia pestis biovar Microtus str. 91001],... gi\|115349146, gi... - gi\|218930535\|ref\|YP_002348410.1\| inorganic pyrophosphatase [Yersinia pestis CO92], gi\|16123667\|ref\|N... IPYR_YERPE - Inorganic pyrophosphatase OS=Yersinia pestis GN=ppa PE=3 SV=1	265.0	[0..1]	[175..1]
gi\|238792995, gi... - gi\|77977606\|ref\|ZP_00833050.1\| COG0221: Inorganic pyrophosphatase [Yersinia intermedia ATCC 29909], ...	264.0	[0..1]	[175..1]
gi\|56480564, gi\|... - gi\|56480564\|ref\|NP_709975.2\| inorganic pyrophosphatase [Shigella flexneri 2a str. 301], gi\|56384115\|... gi\|30065484, gi\|... - gi\|30065484\|ref\|NP_839655.1\| inorganic pyrophosphatase [Shigella flexneri 2a str. 2457T], gi\|3004374... gi\|110808031, gi... - gi\|110808031\|ref\|YP_691551.1\| inorganic pyrophosphatase [Shigella flexneri 5 str. 8401], gi\|11061757...	264.0	[0..1]	[176..1]
IPYR_RALSO - Inorganic pyrophosphatase OS=Ralstonia solanacearum GN=ppa PE=3 SV=1 IPYR_RALSO - Inorganic pyrophosphatase OS=Ralstonia solanacearum (strain GMI1000) GN=ppa PE=3 SV=1	264.0	[0..1]	[175..1]
gi\|238718574, gi... - gi\|77961844\|ref\|ZP_00825673.1\| COG0221: Inorganic pyrophosphatase [Yersinia mollaretii ATCC 43969], ...	264.0	[0..1]	[175..1]
gi\|206588819, gi... - gi\|207723616\|ref\|YP_002254014.1\| inorganic pyrophosphatase (pyrophosphate phospho-hydrolase) (ppase)... gi\|206594066, gi... - gi\|207742672\|ref\|YP_002259064.1\| inorganic pyrophosphatase (pyrophosphate phospho-hydrolase) (ppase)... gi\|83749200, gi\|... - gi\|83749200\|ref\|ZP_00946202.1\| Inorganic pyrophosphatase [Ralstonia solanacearum UW551], gi\|83724141...	264.0	[0..1]	[175..1]

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Predicted Domain #1

Region A:
Residues: [1-176]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLLNVPAGK DLPEDIYVVI EIPANADPIK YEIDKESGAL FVDRFMSTAM FYPCNYGYIN  60
   61 HTLSLDGDPV DVLVPTPYPL QPGSVIRCRP VGVLKMTDEA GEDAKLVAVP HSKLSKEYDH 120
  121 IKDVNDLPEL LKAQIAHFFE HYKDLEKGKW VKVEGWENAE AAKAEIVASF ERAKNK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	70.69897
Match:	1fajA
Description:	INORGANIC PYROPHOSPHATASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
inorganic diphosphatase activity	2.74116819406619	bayes_pls_golite062009
catalytic activity	1.33262120571864	bayes_pls_golite062009
binding	0.737012988130381	bayes_pls_golite062009
hydrolase activity	0.622613523623213	bayes_pls_golite062009
protein binding	0.30018672253552	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.130183342564216	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.129135337748915	bayes_pls_golite062009
pyrophosphatase activity	0.125429411374269	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: