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View Structure Prediction Details

Protein: gi|67515415, gi|...
Organism: Homo sapiens
Length: 497 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|67515415, gi|....

Description E-value Query
Range
Subject
Range
gi|4758354, gi|1... - gi|4758354|ref|NP_004101.1| ferredoxin reductase isoform 2 precursor [Homo sapiens], gi|178214|gb|AA...
2.0E-79 [1..497] [1..497]
gi|61372884, gi|... - gi|61372884|gb|AAX43930.1| ferredoxin reductase [synthetic construct], gi|30585241|gb|AAP36893.1| Ho...
4.0E-79 [1..497] [1..491]
gi|109118124 - gi|109118124|ref|XP_001091504.1| PREDICTED: similar to ferredoxin reductase isoform 2 precursor isof...
9.0E-79 [1..497] [1..497]
gi|625391, gi|45... - pir||JT0751 ferredoxin-NADP reductase (EC 1.18.1.2), long form precursor - bovine, gi|4521308|dbj|BA...
3.0E-75 [1..497] [1..498]
gi|114670364 - gi|114670364|ref|XP_001137746.1| PREDICTED: ferredoxin reductase isoform 2 [Pan troglodytes]
3.0E-74 [1..497] [1..494]

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Predicted Domain #1
Region A:
Residues: [1-497]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASRCWRWWG WSAWPRTRLP PAGSTPSFCH HFSTQEKTPQ ICVVGSGPAG FYTAQHLLKH  60
   61 PQAHVDIYEK QPVPFGLVRF GVAPDHPEVK NVINTFTQTA HSGRCAFWGN VEVGRDVTVP 120
  121 ELREAYHAVV LSYGAEDHRA LEIPGEELPG VCSARAFVGW YNGLPENQEL EPDLSCDTAV 180
  181 ILGQGNVALD VARILLTPPE HLEALLLCQR TDITKAALGV LRQSRVKTVW LVGRRGPLQV 240
  241 AFTIKELREM IQLPGARPIL DPVDFLGLQD KIKEVPRPRK RLTELLLRTA TEKPGPAEAA 300
  301 RQASASRAWG LRFFRSPQQV LPSPDGRRAA GVRLAVTRLE GVDEATRAVP TGDMEDLPCG 360
  361 LVLSSIGYKS RPVDPSVPFD SKLGVIPNVE GRVMDVPGLY CSGWVKRGPT GVIATTMTDS 420
  421 FLTGQMLLQD LKAGLLPSGP RPGYAAIQAL LSSRGVRPVS FSDWEKLDAE EVARGQGTGK 480
  481 PREKLVDPQE MLRLLGH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 65.69897
Match: 1cjcA
Description: Adrenodoxin reductase of mitochondrial p450 systems
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
NADPH-adrenodoxin reductase activity 5.80270482091908 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 4.45434904225178 bayes_pls_golite062009
oxidoreductase activity 2.10828870968712 bayes_pls_golite062009
antioxidant activity 1.49429830917872 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 1.39990343076756 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors 1.29733355244701 bayes_pls_golite062009
catalytic activity 1.13824203225664 bayes_pls_golite062009
thioredoxin-disulfide reductase activity 0.844975371289313 bayes_pls_golite062009
binding 0.794954996246594 bayes_pls_golite062009
dihydrolipoyl dehydrogenase activity 0.68737141906442 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors 0.379282693663222 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor 0.31095562417378 bayes_pls_golite062009
oxygen-dependent protoporphyrinogen oxidase activity 0.0706880697754912 bayes_pls_golite062009
protein binding 0.0171008177759692 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle