YRC Public Data Repository - Protein Structure Prediction

Protein:	DEOD_ECOLI
Organism:	Escherichia coli
Length:	239 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DEOD_ECOLI.

Description	E-value	Query Range	Subject Range
DEOD_PHOLL - Purine nucleoside phosphorylase deoD-type OS=Photorhabdus luminescens subsp. laumondii GN=deoD PE=3 ... DEOD_PHOLL - Purine nucleoside phosphorylase DeoD-type OS=Photorhabdus luminescens subsp. laumondii (strain DSM 1...	217.0	[0..1]	[238..1]
gi\|84387263, gi\|... - gi\|84387263\|ref\|ZP_00990284.1\| purine nucleoside phosphorylase [Vibrio splendidus 12B01], gi\|8437791...	214.0	[0..1]	[239..1]
gi\|85834781, gi\|... - gi\|86147488\|ref\|ZP_01065800.1\| purine nucleoside phosphorylase [Vibrio sp. MED222], gi\|85834781\|gb\|E...	214.0	[0..1]	[239..1]
DEOD_XENNA - Purine nucleoside phosphorylase DeoD-type OS=Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 /... DEOD_XENNE - Purine nucleoside phosphorylase deoD-type OS=Xenorhabdus nematophilus GN=deoD PE=3 SV=1	214.0	[0..1]	[234..1]
gi\|89072595, gi\|... - gi\|89072595\|ref\|ZP_01159167.1\| purine nucleoside phosphorylase [Photobacterium sp. SKA34], gi\|890516...	213.0	[0..1]	[239..1]
gi\|90326543, gi\|... - gi\|90412506\|ref\|ZP_01220509.1\| purine nucleoside phosphorylase [Photobacterium profundum 3TCK], gi\|9... DEOD1_PHOPR - Purine nucleoside phosphorylase DeoD-type 1 OS=Photobacterium profundum (strain SS9) GN=deoD1 PE=3 S... DEOD1_PHOPR - Purine nucleoside phosphorylase DeoD-type 1 OS=Photobacterium profundum GN=deoD1 PE=3 SV=1	213.0	[0..1]	[239..1]
gi\|90437290, gi\|... - gi\|90581528\|ref\|ZP_01237321.1\| purine nucleoside phosphorylase [Vibrio angustum S14], gi\|90437290\|gb...	212.0	[0..1]	[239..1]
gi\|91228292, gi\|... - gi\|91228292\|ref\|ZP_01262228.1\| purine nucleoside phosphorylase [Vibrio alginolyticus 12G01], gi\|9118...	212.0	[0..1]	[239..1]
DEOD_SALTY - Purine nucleoside phosphorylase deoD-type OS=Salmonella typhimurium GN=deoD PE=3 SV=1 DEOD_SALHS - Purine nucleoside phosphorylase DeoD-type OS=Salmonella heidelberg (strain SL476) GN=deoD PE=3 SV=1 gi\|205336642, gi... - gi\|205336642\|gb\|EDZ23406.1\| purine nucleoside phosphorylase [Salmonella enterica subsp. enterica ser... gi\|205331456, gi... - gi\|205331456\|gb\|EDZ18220.1\| purine nucleoside phosphorylase [Salmonella enterica subsp. enterica ser... lcl\|NC_016856.1_... - [gene=deoD] [protein=purine nucleoside phosphorylase] [protein_id=YP_005240914.1] [location=4837974.... DEOD_SALTY - Purine nucleoside phosphorylase deoD-type OS=Salmonella typhimurium GN=deoD PE=3 SV=1 DEOD_SALTY - Purine nucleoside phosphorylase DeoD-type OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 70... gi\|197240110, gi... - gi\|197261855\|ref\|ZP_03161929.1\| purine nucleoside phosphorylase [Salmonella enterica subsp. enterica...	212.0	[0..1]	[239..1]
gi\|227885127, gi... - gi\|227885127\|ref\|ZP_04002932.1\| purine-nucleoside phosphorylase [Escherichia coli 83972], gi\|2278379... gi\|26111707, gi\|... - gi\|26251274\|ref\|NP_757314.1\| purine nucleoside phosphorylase [Escherichia coli CFT073], gi\|26111707\|...	212.0	[0..1]	[239..20]

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Predicted Domain #1

Region A:
Residues: [1-239]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATPHINAEM GDFADVVLMP GDPLRAKYIA ETFLEDAREV NNVRGMLGFT GTYKGRKISV  60
   61 MGHGMGIPSC SIYTKELITD FGVKKIIRVG SCGAVLPHVK LRDVVIGMGA CTDSKVNRIR 120
  121 FKDHDFAAIA DFDMVRNAVD AAKALGIDAR VGNLFSADLF YSPDGEMFDV MEKYGILGVE 180
  181 MEAAGIYGVA AEFGAKALTI CTVSDHIRTH EQTTAAERQT TFNDMIKIAL ESVLLGDKE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	55.0
Match:	1pr0A
Description:	Escherichia coli Purine Nucleoside Phosphorylase Complexed with Inosine and Phosphate/Sulfate
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
purine-nucleoside phosphorylase activity	3.68206997938506	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	3.66765825367784	bayes_pls_golite062009
catalytic activity	2.18268586151113	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	2.01261001022129	bayes_pls_golite062009
S-methyl-5-thioadenosine phosphorylase activity	1.6959166270803	bayes_pls_golite062009
transferase activity	1.42022417161912	bayes_pls_golite062009
nucleobase binding	1.33291775180025	bayes_pls_golite062009
nucleoside binding	1.11256863177576	bayes_pls_golite062009
purine binding	1.00226077276304	bayes_pls_golite062009
binding	0.192121943858605	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: