YRC Public Data Repository - Protein Structure Prediction

Protein:	CYSC_ECOLI
Organism:	Escherichia coli
Length:	201 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CYSC_ECOLI.

Description	E-value	Query Range	Subject Range
CYSC_MARHV - Adenylyl-sulfate kinase OS=Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)...	225.0	[0..6]	[201..2]
gi\|56962388, gi\|... - gi\|56962388\|ref\|YP_174114.1\| adenylylsulfate kinase [Bacillus clausii KSM-K16], gi\|56908626\|dbj\|BAD6...	224.0	[0..1]	[199..1]
gi\|88786272, gi\|... - gi\|88809888\|ref\|ZP_01125394.1\| Adenylylsulfate kinase [Synechococcus sp. WH 7805], gi\|88786272\|gb\|EA...	218.0	[0..5]	[201..16]
gi\|110284175, gi... - gi\|69280172\|ref\|ZP_00614844.1\| Adenylylsulfate kinase [Mesorhizobium sp. BNC1], gi\|68189596\|gb\|EAN04...	218.0	[0..4]	[198..444]
gi\|56378791, gi\|... - gi\|56418949\|ref\|YP_146267.1\| adenylylsulfate kinase [Geobacillus kaustophilus HTA426], gi\|56378791\|d...	217.0	[0..5]	[201..2]
gi\|78213928, gi\|... - gi\|78213928\|ref\|YP_382707.1\| adenylylsulfate kinase [Synechococcus sp. CC9605], gi\|78198387\|gb\|ABB36...	217.0	[0..1]	[201..10]
gi\|78185667, gi\|... - gi\|78185667\|ref\|YP_378101.1\| adenylylsulfate kinase [Synechococcus sp. CC9902], gi\|78169961\|gb\|ABB27...	216.0	[0..2]	[201..13]
gi\|86169304, gi\|... - gi\|87123584\|ref\|ZP_01079435.1\| Adenylylsulfate kinase [Synechococcus sp. RS9917], gi\|86169304\|gb\|EAQ...	215.0	[0..2]	[201..8]
gi\|116065668, gi... - gi\|116072045\|ref\|ZP_01469313.1\| Adenylylsulfate kinase [Synechococcus sp. BL107], gi\|116065668\|gb\|EA...	215.0	[0..2]	[201..5]
CYSC_OCEIH - Adenylyl-sulfate kinase OS=Oceanobacillus iheyensis GN=cysC PE=3 SV=1 CYSC_OCEIH - Adenylyl-sulfate kinase OS=Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE8...	215.0	[0..2]	[199..1]

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Predicted Domain #1

Region A:
Residues: [1-201]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALHDENVVW HSHPVTVQQR ELHHGHRGVV LWFTGLSGSG KSTVAGALEE ALHKLGVSTY  60
   61 LLDGDNVRHG LCSDLGFSDA DRKENIRRVG EVANLMVEAG LVVLTAFISP HRAERQMVRE 120
  121 RVGEGRFIEV FVDTPLAICE ARDPKGLYKK ARAGELRNFT GIDSVYEAPE SAEIHLNGEQ 180
  181 LVTNLVQQLL DLLRQNDIIR S

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	55.30103
Match:	1x6vB
Description:	The crystal structure of human 3'-phosphoadenosine-5'-phosphosulfate synthetase 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.0914769303586	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
nucleic acid binding	0.727912309521959	bayes_pls_golite062009
DNA binding	0.263924823205515	bayes_pls_golite062009
nucleotide binding	0.0593371872166591	bayes_pls_golite062009
purine nucleotide binding	0.0285347443435678	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: