YRC Public Data Repository - Protein Structure Prediction

Protein:	IF1_ECOLI
Organism:	Escherichia coli
Length:	72 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IF1_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|82947279, gi\|... - gi\|83312438\|ref\|YP_422702.1\| translation initiation factor 1 [Magnetospirillum magneticum AMB-1], gi...	2.0E-34	[1..72]	[57..128]
gi\|25027124, gi\|... - gi\|25027124\|ref\|NP_737178.1\| translation initiation factor IF-1 [Corynebacterium efficiens YS-314], ...	1.0E-33	[1..72]	[48..119]
IF1_RUBXD - Translation initiation factor IF-1 OS=Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) GN=inf...	1.0E-32	[1..72]	[1..72]
IF1_BACSK - Translation initiation factor IF-1 OS=Bacillus clausii (strain KSM-K16) GN=infA PE=3 SV=1	4.0E-32	[1..72]	[1..72]
gi\|67987510, gi\|... - gi\|69285459\|ref\|ZP_00616945.1\| Translation initiation factor IF-1 [Kineococcus radiotolerans SRS3021...	4.0E-32	[1..72]	[54..126]
IF1_BACHD - Translation initiation factor IF-1 OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 73... IF1_BACHD - Translation initiation factor IF-1 OS=Bacillus halodurans GN=infA PE=3 SV=3	5.0E-32	[1..72]	[1..72]
gi\|88932100, gi\|... - gi\|88932100\|ref\|ZP_01137792.1\| Translation initiation factor IF-1 [Acidothermus cellulolyticus 11B],...	6.0E-32	[1..72]	[69..141]
gi\|145305748, gi... - gi\|145596411\|ref\|YP_001160708.1\| translation initiation factor IF-1 [Salinispora tropica CNB-440], g...	6.0E-32	[1..72]	[81..153]
gi\|89158923, gi\|... - gi\|89211455\|ref\|ZP_01189819.1\| Translation initiation factor IF-1 [Halothermothrix orenii H 168], gi...	7.0E-32	[1..72]	[1..72]
IF1_STAA9 - Translation initiation factor IF-1 OS=Staphylococcus aureus (strain JH9) GN=infA PE=3 SV=1 IF1_STAAT - Translation initiation factor IF-1 OS=Staphylococcus aureus (strain USA300 / TCH1516) GN=infA PE=3 S... IF1_STAAC - Translation initiation factor IF-1 OS=Staphylococcus aureus (strain COL) GN=infA PE=3 SV=1 gi\|269203861\|ref... - translation initiation factor IF-1 [Staphylococcus aureus subsp. aureus ED98] IF1_STAAE - Translation initiation factor IF-1 OS=Staphylococcus aureus (strain Newman) GN=infA PE=3 SV=1 IF1_STAA1 - Translation initiation factor IF-1 OS=Staphylococcus aureus (strain Mu3 / ATCC 700698) GN=infA PE=3 ... gi\|255007008 - gi\|255007008\|ref\|ZP_05145609.2\| translation initiation factor IF-1 [Staphylococcus aureus subsp. aur... gi\|253727680, gi... - gi\|253734363\|ref\|ZP_04868528.1\| translation initiation factor IF-1 [Staphylococcus aureus subsp. aur... gi\|253729894, gi... - gi\|253729894\|ref\|ZP_04864059.1\| translation initiation factor IF-1 [Staphylococcus aureus subsp. aur... gi\|222119589, gi... - gi\|222150467\|ref\|YP_002559620.1\| translation initiation factor IF-1 [Macrococcus caseolyticus JCSC54... gi\|253316989 - gi\|253316989\|ref\|ZP_04840202.1\| translation initiation factor IF-1 [Staphylococcus aureus subsp. aur... gi\|224477198, gi... - gi\|224477198\|ref\|YP_002634804.1\| translation initiation factor IF-1 [Staphylococcus carnosus subsp. ... gi\|251803118, gi... - gi\|251813345\|ref\|ZP_04827818.1\| translation initiation factor IF-1 [Staphylococcus aureus subsp. aur... gi\|227899001, gi... - gi\|227899001\|ref\|ZP_04016806.1\| translation initiation factor IF-1 [Staphylococcus aureus subsp. aur... gi\|227556941, gi... - gi\|227556941\|ref\|ZP_03986988.1\| translation initiation factor IF-1 [Staphylococcus aureus subsp. aur... gi\|87127053\|gb\|A... - translation initiation factor IF-1 [Staphylococcus aureus subsp. aureus USA300], translation initiat... IF1_STAAM - Translation initiation factor IF-1 OS=Staphylococcus aureus (strain Mu50 / ATCC 700699) GN=infA PE=3... IF1_STAAN - Translation initiation factor IF-1 OS=Staphylococcus aureus (strain N315) GN=infA PE=1 SV=1 IF1_STAAW - Translation initiation factor IF-1 OS=Staphylococcus aureus (strain MW2) GN=infA PE=3 SV=1 gi\|221138930 - gi\|221138930\|ref\|ZP_03563731.1\| translation initiation factor IF-1 [Staphylococcus aureus subsp. aur... gi\|221140170 - gi\|221140170\|ref\|ZP_03564663.1\| translation initiation factor IF-1 [Staphylococcus aureus subsp. aur... IF1_STAAB - Translation initiation factor IF-1 OS=Staphylococcus aureus (strain bovine RF122 / ET3-1) GN=infA PE... IF1_STAAR - Translation initiation factor IF-1 OS=Staphylococcus aureus (strain MRSA252) GN=infA PE=3 SV=1 IF1_STAAS - Translation initiation factor IF-1 OS=Staphylococcus aureus (strain MSSA476) GN=infA PE=3 SV=1 gi\|25299556 - pir\|\|G90019 translation initiation factor IF-1 [imported] - Staphylococcus aureus (strain N315) IF1_STAA2 - Translation initiation factor IF-1 OS=Staphylococcus aureus (strain JH1) GN=infA PE=3 SV=1 IF1_STAA8 - Translation initiation factor IF-1 OS=Staphylococcus aureus (strain NCTC 8325) GN=infA PE=3 SV=1 IF1_STAS1 - Translation initiation factor IF-1 OS=Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC... IF1_STAA3 - Translation initiation factor IF-1 OS=Staphylococcus aureus (strain USA300) GN=infA PE=3 SV=1	8.0E-32	[1..72]	[1..72]

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Predicted Domain #1

Region A:
Residues: [1-72]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKEDNIEMQ GTVLETLPNT MFRVELENGH VVTAHISGKM RKNYIRILTG DKVTVELTPY  60
   61 DLSKGRIVFR SR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.0
Match:	1ah9A
Description:	THE STRUCTURE OF THE TRANSLATIONAL INITIATION FACTOR IF1 FROM ESCHERICHIA COLI, NMR, 19 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
translation initiation factor activity	3.7577199572893	bayes_pls_golite062009
nucleic acid binding	1.65948797337693	bayes_pls_golite062009
structural constituent of ribosome	1.48826676464117	bayes_pls_golite062009
structural molecule activity	1.20191382777151	bayes_pls_golite062009
binding	0.902189695502298	bayes_pls_golite062009
DNA binding	0.9001707539121	bayes_pls_golite062009
translation regulator activity	0.75912526777056	bayes_pls_golite062009
translation factor activity, nucleic acid binding	0.71309127606641	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: