YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|22128000, gi\|...
Organism:	Yersinia pestis KIM10+
Length:	609 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|22128000, gi|....

Description	E-value	Query Range	Subject Range
gi\|83571319, gi\|... - gi\|83571319\|ref\|ZP_00922759.1\| COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferas...	0.0	[1..609]	[1..609]
gi\|73857722, gi\|... - gi\|74314245\|ref\|YP_312664.1\| D-fructose-6-phosphate amidotransferase [Shigella sonnei Ss046], gi\|738...	0.0	[1..609]	[1..609]
gi\|187733589, gi... - gi\|75177701\|ref\|ZP_00697766.1\| COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferas...	0.0	[1..609]	[1..609]
gi\|115515126, gi... - gi\|117626002\|ref\|YP_859325.1\| D-fructose-6-phosphate amidotransferase [Escherichia coli APEC O1], gi...	0.0	[1..609]	[1..609]
gi\|82779079, gi\|... - gi\|82779079\|ref\|YP_405428.1\| D-fructose-6-phosphate amidotransferase [Shigella dysenteriae Sd197], g...	0.0	[1..609]	[1..609]
gi\|170681402, gi... - gi\|170681402\|ref\|YP_001746059.1\| glutamine-fructose-6-phosphate transaminase (isomerizing) [Escheric... gi\|218372565, gi... - gi\|218702579\|ref\|YP_002410208.1\| glucosamine--fructose-6-phosphate aminotransferase [Escherichia col... gi\|215267139, gi... - gi\|215489067\|ref\|YP_002331498.1\| glucosamine--fructose-6-phosphate aminotransferase [Escherichia col... gi\|226902794, gi... - gi\|237703530\|ref\|ZP_04534011.1\| L-glutamine:D-fructose-6-phosphate aminotransferase [Escherichia sp.... gi\|218707375, gi... - gi\|218707375\|ref\|YP_002414894.1\| glucosamine--fructose-6-phosphate aminotransferase [Escherichia col... GLMS_SHIFL - Glutamine--fructose-6-phosphate aminotransferase [isomerizing] OS=Shigella flexneri GN=glmS PE=3 SV=... gi\|110617101, gi... - gi\|110807553\|ref\|YP_691073.1\| D-fructose-6-phosphate amidotransferase [Shigella flexneri 5 str. 8401... gi\|24054291, gi\|... - gi\|24115032\|ref\|NP_709542.1\| D-fructose-6-phosphate amidotransferase [Shigella flexneri 2a str. 301]... gi\|188489293, gi... - gi\|75514205\|ref\|ZP_00736513.1\| COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferas... gi\|30043227, gi\|... - gi\|30064966\|ref\|NP_839137.1\| D-fructose-6-phosphate amidotransferase [Shigella flexneri 2a str. 2457... gi\|91213253, gi\|... - gi\|91213253\|ref\|YP_543239.1\| D-fructose-6-phosphate amidotransferase [Escherichia coli UTI89], gi\|91...	0.0	[1..609]	[1..609]
gi\|190909109, gi... - gi\|75242483\|ref\|ZP_00726227.1\| COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferas... gi\|110345662, gi... - gi\|110644070\|ref\|YP_671800.1\| glucosamine--fructose-6-phosphate aminotransferase [Escherichia coli 5...	0.0	[1..609]	[1..609]
gi\|83588406, gi\|... - gi\|83588406\|ref\|ZP_00927030.1\| COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferas... gi\|157080617, gi... - gi\|75188487\|ref\|ZP_00701754.1\| COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferas... gi\|157068890, gi... - gi\|75197625\|ref\|ZP_00707695.1\| COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferas... gi\|75210661, gi\|... - gi\|75210661\|ref\|ZP_00710802.1\| COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferas... EG10382 - L-glutamine:D-fructose-6-phosphate aminotransferase / Glucosamine-6-phosphate synthase; glucosamine-... gi\|191165793, gi... - gi\|75230998\|ref\|ZP_00717433.1\| COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferas... gi\|192957549, gi... - gi\|75236461\|ref\|ZP_00720557.1\| COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferas... gi\|193063823, gi... - gi\|75258268\|ref\|ZP_00729716.1\| COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferas... GLMS_ECOLI - Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) (Hexosephosphate amin... gi\|85676309, gi\|... - gi\|89110278\|ref\|AP_004058.1\| L-glutamine:D-fructose-6-phosphate aminotransferase [Escherichia coli s... gi\|169757162, gi... - gi\|170022234\|ref\|YP_001727188.1\| glucosamine--fructose-6-phosphate aminotransferase [Escherichia col... gi\|209921210, gi... - gi\|209921210\|ref\|YP_002295294.1\| glucosamine--fructose-6-phosphate aminotransferase [Escherichia col... gi\|238861652, gi... - gi\|238902820\|ref\|YP_002928616.1\| L-glutamine:D-fructose-6-phosphate aminotransferase [Escherichia co... gi\|218354187, gi... - gi\|218697455\|ref\|YP_002405122.1\| glucosamine--fructose-6-phosphate aminotransferase [Escherichia col... gi\|242379267, gi... - gi\|251786994\|ref\|YP_003001298.1\| hypothetical protein B21_03557 [Escherichia coli BL21], gi\|24237926... gi\|254290431, gi... - gi\|254290431\|ref\|YP_003056179.1\| D-fructose-6-phosphate amidotransferase [Escherichia coli BL21(DE3)... gi\|226838913, gi... - gi\|254038948\|ref\|ZP_04873000.1\| glutamine-fructose-6-phosphate transaminase [Escherichia sp. 1_1_43]... gi\|254163681, gi... - gi\|254163681\|ref\|YP_003046789.1\| D-fructose-6-phosphate amidotransferase [Escherichia coli B str. RE... EG10382 - L-glutamine:D-fructose-6-phosphate aminotransferase / Glucosamine-6-phosphate synthase; glucosamine-... gi\|124530057, gi... - gi\|124530057\|ref\|ZP_01700840.1\| glucosamine--fructose-6-phosphate aminotransferase, isomerizing [Esc...	0.0	[1..609]	[1..609]
gi\|73671334\|gb\|A... - GlmS variant [Escherichia coli] gi\|73671334 - gi\|73671334\|gb\|AAZ80078.1\| GlmS variant [Escherichia coli]	0.0	[1..609]	[1..609]
gi\|82546110, gi\|... - gi\|82546110\|ref\|YP_410057.1\| D-fructose-6-phosphate amidotransferase [Shigella boydii Sb227], gi\|812...	0.0	[1..609]	[1..609]

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Predicted Domain #1

Region A:
Residues: [1-609]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCGIVGAVAQ RDIAEILIEG LRRLEYRGYD SAGLAVVDSE GHLTRLRRVG KVHALSDAAE  60
   61 KQDLHGGTGI AHTRWATHGE PSEANAHPHV SDYISVVHNG IIENHEPLRE LLISRGYRFS 120
  121 SETDTEVIAH LVHWEQQQGG SLLEVVKRVI PQLRGAYGTV VMDSRDPSRL IAARSGSPLV 180
  181 IGCGVGENFI ASDQLALLPV TRRFIFLEEG DVVEVTRRSI SIFDKQGNAI ERPEIESQVQ 240
  241 YDAGDKGIYR HYMQKEIYEQ PMAIKNTLEG RLSHGMIDLS ELGPKADALL AEVQHIQIIA 300
  301 CGTSYNSGMV SRYWFESLAG VPCDVEIASE FRYRKSAVRP NSLLITLSQS GETADTLAAL 360
  361 RLSKELGYLG SLAICNVAGS SLVRESDLAL MTKAGTEIGV ASTKAFTTQL TVLLMLVGRI 420
  421 GKLKGADASL EHDIVHALQA LPARIEQMLS LDKTIEALAE GFSDKHHALF LGRGDQYPIA 480
  481 MEGALKLKEI SYIHAEAYAA GELKHGPLAL IDADMPVIVV APNNELLEKL KSNIEEVRAR 540
  541 GGLLYVFADQ DAGFTDSEGM KIIQLPHVEE IIAPIFYTVP LQLLSYHVAL IKGTDVDQPR 600
  601 NLAKSVTVE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	167.0
Match:	1jxaA
Description:	"Isomerase domain" of glucosamine 6-phosphate synthase (GLMS); Glucosamine 6-phosphate synthase, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glutamine-fructose-6-phosphate transaminase (isomerizing) activity	4.12465195642555	bayes_pls_golite062009
glucose-6-phosphate isomerase activity	2.74527495029339	bayes_pls_golite062009
D-sedoheptulose 7-phosphate isomerase activity	2.03357282678145	bayes_pls_golite062009
intramolecular oxidoreductase activity	1.99606027864666	bayes_pls_golite062009
catalytic activity	1.5278037255884	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses	1.49939040101274	bayes_pls_golite062009
sugar binding	1.40175307923331	bayes_pls_golite062009
peptidase activity	1.34295853726897	bayes_pls_golite062009
transferase activity	1.20219571915061	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	1.16226272745141	bayes_pls_golite062009
isomerase activity	0.875614547872629	bayes_pls_golite062009
binding	0.8320110584046	bayes_pls_golite062009
nucleic acid binding	0.798789250029517	bayes_pls_golite062009
endopeptidase activity	0.759765292911898	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	0.329741341879618	bayes_pls_golite062009
transaminase activity	0.307877519336205	bayes_pls_golite062009
protein binding	0.152745336606766	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: