YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|29140683, gi\|...
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. Ty2
Length:	329 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|29140683, gi|....

Description	E-value	Query Range	Subject Range
gi\|115365408, gi... - gi\|115377607\|ref\|ZP_01464804.1\| aldo/keto reductase [Stigmatella aurantiaca DW4/3-1], gi\|115365408\|g...	3.0E-98	[1..329]	[1..329]
gi\|85775968, gi\|... - gi\|86159457\|ref\|YP_466242.1\| aldo/keto reductase [Anaeromyxobacter dehalogenans 2CP-C], gi\|85775968\|...	4.0E-97	[1..328]	[1..327]
gi\|50119681, gi\|... - gi\|50119681\|ref\|YP_048848.1\| putative aldo/keto reductase [Pectobacterium atrosepticum SCRI1043], gi...	8.0E-97	[1..328]	[1..329]
gi\|148265548, gi... - gi\|88934427\|ref\|ZP_01140070.1\| probable oxidoreductase [Geobacter uraniumreducens Rf4], gi\|88918885\|...	2.0E-95	[1..329]	[1..328]
gi\|186684841, gi... - gi\|23125522\|ref\|ZP_00107451.1\| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydroge...	2.0E-94	[1..329]	[1..326]
gi\|68179876, gi\|... - gi\|95929754\|ref\|ZP_01312495.1\| aldo/keto reductase [Desulfuromonas acetoxidans DSM 684], gi\|95134050...	2.0E-94	[1..329]	[1..328]
gi\|68513185, gi\|... - gi\|68560654\|ref\|ZP_00599965.1\| Aldo/keto reductase [Rubrobacter xylanophilus DSM 9941], gi\|68513185\|...	4.0E-94	[1..329]	[1..327]
gi\|53761677, gi\|... - gi\|73543064\|ref\|YP_297584.1\| aldo/keto reductase [Ralstonia eutropha JMP134], gi\|72120477\|gb\|AAZ6274...	5.0E-94	[3..329]	[13..340]
gi\|66780950, gi\|... - gi\|94986270\|ref\|YP_605634.1\| aldo/keto reductase [Deinococcus geothermalis DSM 11300], gi\|94556551\|g...	7.0E-94	[1..329]	[1..324]
gi\|108757429, gi... - gi\|108757429\|ref\|YP_628583.1\| aldo/keto reductase family oxidoreductase [Myxococcus xanthus DK 1622]...	1.0E-93	[1..327]	[1..327]

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Predicted Domain #1

Region A:
Residues: [1-329]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQYRTLGANG PRVSAIGLGC MGMSAFYGAH DDSTSIKTLH YALDQGVTLL DTADMYGPYT  60
   61 NERLVGRAIA DRRDRVFLAT KFGIVLDPAN PMARGVNGRP EYVRRSCEQS LQRLGVDHID 120
  121 LYYQHRVDPS VPIEETVGAM ADLVREGKVR YLGLSEASTQ TLERAHNVHP ITALQSEYSL 180
  181 WSREAEISAL STCERLGIGF VAYSPLGRGF LTGTIKTPED FAANDFRRTN PRFMGENFSR 240
  241 NLRLAEAIKQ MAREKECTPA QLALAWLLAR NRHLVPIPGT RHCARVDENL GALSLTLSPQ 300
  301 ELAAIEAVFP HDAAAGPRYW PEIMSTLNR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	79.09691
Match:	1pyfA
Description:	Structure of NADPH-dependent family 11 aldo-keto reductase AKR11A(apo)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
aldehyde reductase activity	5.07106269693426	bayes_pls_golite062009
xylose reductase activity	3.28910924444005	bayes_pls_golite062009
arabinose reductase activity	3.28910924444005	bayes_pls_golite062009
pyridoxine 4-dehydrogenase activity	3.25535446462297	bayes_pls_golite062009
glucose 1-dehydrogenase (NADP+) activity	2.68048267823456	bayes_pls_golite062009
aldo-keto reductase activity	2.57303336304449	bayes_pls_golite062009
aryl-alcohol dehydrogenase activity	2.5168190536972	bayes_pls_golite062009
catalytic activity	1.68179794468736	bayes_pls_golite062009
glucose 1-dehydrogenase activity	1.55697325009049	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.48881830724998	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.47641884930911	bayes_pls_golite062009
binding	0.633340939735849	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: