YRC Public Data Repository - Protein Structure Prediction

Protein:	GLMS_ECOLI
Organism:	Escherichia coli
Length:	609 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLMS_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|73857722, gi\|... - gi\|74314245\|ref\|YP_312664.1\| D-fructose-6-phosphate amidotransferase [Shigella sonnei Ss046], gi\|738...	635.0	[0..1]	[609..1]
gi\|187733589, gi... - gi\|75177701\|ref\|ZP_00697766.1\| COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferas...	634.0	[0..1]	[609..1]
gi\|115515126, gi... - gi\|117626002\|ref\|YP_859325.1\| D-fructose-6-phosphate amidotransferase [Escherichia coli APEC O1], gi...	634.0	[0..1]	[609..1]
gi\|83571319, gi\|... - gi\|83571319\|ref\|ZP_00922759.1\| COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferas...	634.0	[0..1]	[609..1]
gi\|170681402, gi... - gi\|170681402\|ref\|YP_001746059.1\| glutamine-fructose-6-phosphate transaminase (isomerizing) [Escheric... gi\|218372565, gi... - gi\|218702579\|ref\|YP_002410208.1\| glucosamine--fructose-6-phosphate aminotransferase [Escherichia col... gi\|215267139, gi... - gi\|215489067\|ref\|YP_002331498.1\| glucosamine--fructose-6-phosphate aminotransferase [Escherichia col... gi\|226902794, gi... - gi\|237703530\|ref\|ZP_04534011.1\| L-glutamine:D-fructose-6-phosphate aminotransferase [Escherichia sp.... gi\|218707375, gi... - gi\|218707375\|ref\|YP_002414894.1\| glucosamine--fructose-6-phosphate aminotransferase [Escherichia col... GLMS_SHIFL - Glutamine--fructose-6-phosphate aminotransferase [isomerizing] OS=Shigella flexneri GN=glmS PE=3 SV=... gi\|110617101, gi... - gi\|110807553\|ref\|YP_691073.1\| D-fructose-6-phosphate amidotransferase [Shigella flexneri 5 str. 8401... gi\|24054291, gi\|... - gi\|24115032\|ref\|NP_709542.1\| D-fructose-6-phosphate amidotransferase [Shigella flexneri 2a str. 301]... gi\|188489293, gi... - gi\|75514205\|ref\|ZP_00736513.1\| COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferas... gi\|30043227, gi\|... - gi\|30064966\|ref\|NP_839137.1\| D-fructose-6-phosphate amidotransferase [Shigella flexneri 2a str. 2457... gi\|91213253, gi\|... - gi\|91213253\|ref\|YP_543239.1\| D-fructose-6-phosphate amidotransferase [Escherichia coli UTI89], gi\|91...	634.0	[0..1]	[609..1]
gi\|190909109, gi... - gi\|75242483\|ref\|ZP_00726227.1\| COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferas... gi\|110345662, gi... - gi\|110644070\|ref\|YP_671800.1\| glucosamine--fructose-6-phosphate aminotransferase [Escherichia coli 5...	634.0	[0..1]	[609..1]
gi\|82546110, gi\|... - gi\|82546110\|ref\|YP_410057.1\| D-fructose-6-phosphate amidotransferase [Shigella boydii Sb227], gi\|812...	634.0	[0..1]	[609..1]
gi\|73671334\|gb\|A... - GlmS variant [Escherichia coli] gi\|73671334 - gi\|73671334\|gb\|AAZ80078.1\| GlmS variant [Escherichia coli]	633.0	[0..1]	[609..1]
gi\|25287308 - pir\|\|G91212 hypothetical protein ECs4671 [imported] - Escherichia coli (strain O157:H7, substrain R... gi\|15833925, gi\|... - gi\|15833925\|ref\|NP_312698.1\| D-fructose-6-phosphate amidotransferase [Escherichia coli O157:H7], gi\|... gi\|15833925, gi\|... - gi\|15833925\|ref\|NP_312698.1\| glucosamine--fructose-6-phosphate aminotransferase [Escherichia coli O1...	633.0	[0..1]	[609..1]
gi\|209158986, gi... - gi\|209397586\|ref\|YP_002273257.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:... gi\|217321769, gi... - gi\|217325548\|ref\|ZP_03441632.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:H... gi\|25287310, gi\|... - pir\|\|H86058 hypothetical protein glmS [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|195936356 - gi\|195936356\|ref\|ZP_03081738.1\| D-fructose-6-phosphate amidotransferase [Escherichia coli O157:H7 st... gi\|208806513, gi... - gi\|208806513\|ref\|ZP_03248850.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:H... gi\|15804329, gi\|... - gi\|15804329\|ref\|NP_290368.1\| D-fructose-6-phosphate amidotransferase [Escherichia coli O157:H7 EDL93... gi\|208734215, gi... - gi\|208812938\|ref\|ZP_03254267.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:H... GLMS_ECO57 - Glutamine--fructose-6-phosphate aminotransferase [isomerizing] OS=Escherichia coli O157:H7 GN=glmS P... gi\|208739668, gi... - gi\|208819545\|ref\|ZP_03259865.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:H... gi\|187771681, gi... - gi\|187771681\|gb\|EDU35525.1\| glutamine-fructose-6-phosphate transaminase (isomerizing) [Escherichia c... gi\|189002421, gi... - gi\|189002421\|gb\|EDU71407.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:H7 st... gi\|189373264, gi... - gi\|189373264\|gb\|EDU91680.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:H7 st... gi\|189378781, gi... - gi\|189378781\|gb\|EDU97197.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:H7 st... gi\|168748541, gi... - gi\|188016915\|gb\|EDU55037.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:H7 st... gi\|254795735, gi... - gi\|254795735\|ref\|YP_003080572.1\| L-glutamine:D-fructose-6-phosphate aminotransferase [Escherichia co... gi\|168753631, gi... - gi\|189359185\|gb\|EDU77604.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:H7 st... gi\|168759929, gi... - gi\|189369471\|gb\|EDU87887.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:H7 st... gi\|168766229, gi... - gi\|189364600\|gb\|EDU83019.1\| glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:H7 st...	632.0	[0..1]	[609..1]

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Predicted Domain #1

Region A:
Residues: [1-609]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCGIVGAIAQ RDVAEILLEG LRRLEYRGYD SAGLAVVDAE GHMTRLRRLG KVQMLAQAAE  60
   61 EHPLHGGTGI AHTRWATHGE PSEVNAHPHV SEHIVVVHNG IIENHEPLRE ELKARGYTFV 120
  121 SETDTEVIAH LVNWELKQGG TLREAVLRAI PQLRGAYGTV IMDSRHPDTL LAARSGSPLV 180
  181 IGLGMGENFI ASDQLALLPV TRRFIFLEEG DIAEITRRSV NIFDKTGAEV KRQDIESNLQ 240
  241 YDAGDKGIYR HYMQKEIYEQ PNAIKNTLTG RISHGQVDLS ELGPNADELL SKVEHIQILA 300
  301 CGTSYNSGMV SRYWFESLAG IPCDVEIASE FRYRKSAVRR NSLMITLSQS GETADTLAGL 360
  361 RLSKELGYLG SLAICNVPGS SLVRESDLAL MTNAGTEIGV ASTKAFTTQL TVLLMLVAKL 420
  421 SRLKGLDASI EHDIVHGLQA LPSRIEQMLS QDKRIEALAE DFSDKHHALF LGRGDQYPIA 480
  481 LEGALKLKEI SYIHAEAYAA GELKHGPLAL IDADMPVIVV APNNELLEKL KSNIEEVRAR 540
  541 GGQLYVFADQ DAGFVSSDNM HIIEMPHVEE VIAPIFYTVP LQLLAYHVAL IKGTDVDQPR 600
  601 NLAKSVTVE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1jxaA
Description:	"Isomerase domain" of glucosamine 6-phosphate synthase (GLMS); Glucosamine 6-phosphate synthase, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glutamine-fructose-6-phosphate transaminase (isomerizing) activity	4.12465195642555	bayes_pls_golite062009
glucose-6-phosphate isomerase activity	2.74527495029339	bayes_pls_golite062009
D-sedoheptulose 7-phosphate isomerase activity	2.03357282678145	bayes_pls_golite062009
intramolecular oxidoreductase activity	1.99606027864666	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses	1.49939040101274	bayes_pls_golite062009
sugar binding	1.40175307923331	bayes_pls_golite062009
catalytic activity	1.19663085909195	bayes_pls_golite062009
isomerase activity	0.875614547872629	bayes_pls_golite062009
nucleic acid binding	0.798789250029517	bayes_pls_golite062009
peptidase activity	0.627053118023721	bayes_pls_golite062009
binding	0.541510243044181	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	0.478737143854577	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	0.329741341879618	bayes_pls_golite062009
transaminase activity	0.307877519336205	bayes_pls_golite062009
endopeptidase activity	0.0940838340168359	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: