YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|4062528, gi\|1...
Organism:	Escherichia coli K-12
Length:	720 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|4062528, gi|1....

Description	E-value	Query Range	Subject Range
gi\|26246982, gi\|... - gi\|26246982\|ref\|NP_753022.1\| hypothetical protein c1097 [Escherichia coli CFT073], gi\|26107382\|gb\|AA... gi\|117623170, gi... - gi\|117623170\|ref\|YP_852083.1\| YccS [Escherichia coli APEC O1], gi\|115512294\|gb\|ABJ00369.1\| YccS [Esc... gi\|226898265, gi... - gi\|237707055\|ref\|ZP_04537536.1\| YccS [Escherichia sp. 3_2_53FAA], gi\|226898265\|gb\|EEH84524.1\| YccS [... gi\|91210056, gi\|... - gi\|91210056\|ref\|YP_540042.1\| hypothetical protein UTI89_C1026 [Escherichia coli UTI89], gi\|91071630\|... gi\|227884080, gi... - gi\|227884080\|ref\|ZP_04001885.1\| membrane protein [Escherichia coli 83972], gi\|227838832\|gb\|EEJ49298....	394.0	[0..1]	[720..1]
gi\|193070046, gi... - gi\|75235202\|ref\|ZP_00719444.1\| COG1289: Predicted membrane protein [Escherichia coli E110019], gi\|19... gi\|75230235, gi\|... - gi\|75230235\|ref\|ZP_00716732.1\| COG1289: Predicted membrane protein [Escherichia coli B7A], gi\|191166...	394.0	[0..1]	[720..1]
gi\|193066700, gi... - gi\|75255128\|ref\|ZP_00727015.1\| COG1289: Predicted membrane protein [Escherichia coli E22], gi\|193066... gi\|75208516, gi\|... - gi\|75208516\|ref\|ZP_00708834.1\| COG1289: Predicted membrane protein [Escherichia coli B171], gi\|19443... gi\|157157855, gi... - gi\|75190028\|ref\|ZP_00703295.1\| COG1289: Predicted membrane protein [Escherichia coli E24377A], gi\|15...	394.0	[0..1]	[720..1]
gi\|84390462, gi\|... - gi\|84390462\|ref\|ZP_00991473.1\| putative efflux (PET) family transporter [Vibrio splendidus 12B01], g...	394.0	[0..5]	[718..3]
gi\|83584618, gi\|... - gi\|83584618\|ref\|ZP_00923287.1\| COG1289: Predicted membrane protein [Escherichia coli 101-1], gi\|1944...	394.0	[0..1]	[720..1]
gi\|15830298, gi\|... - gi\|15830298\|ref\|NP_309071.1\| hypothetical protein ECs1044 [Escherichia coli O157:H7], gi\|13360504\|db... gi\|208725739, gi... - gi\|208805938\|ref\|ZP_03248275.1\| putative membrane protein [Escherichia coli O157:H7 str. EC4206], gi... gi\|195935147 - gi\|195935147\|ref\|ZP_03080529.1\| hypothetical protein EscherichcoliO157_01607 [Escherichia coli O157:... gi\|189376548, gi... - gi\|189376548\|gb\|EDU94964.1\| putative membrane protein [Escherichia coli O157:H7 str. EC508], gi\|1688... gi\|189372609, gi... - gi\|189372609\|gb\|EDU91025.1\| putative membrane protein [Escherichia coli O157:H7 str. EC869], gi\|1687... gi\|217320807, gi... - gi\|217324586\|ref\|ZP_03440670.1\| putative membrane protein [Escherichia coli O157:H7 str. TW14588], g... gi\|25304429, gi\|... - pir\|\|D90759 hypothetical protein ECs1044 [imported] - Escherichia coli (strain O157:H7, substrain R... gi\|209160190, gi... - gi\|209398790\|ref\|YP_002269628.1\| hypothetical protein ECH74115_1123 [Escherichia coli O157:H7 str. E... gi\|15830298, gi\|... - gi\|15830298\|ref\|NP_309071.1\| hypothetical protein ECs1044 [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|208737604, gi... - gi\|208822119\|ref\|ZP_03262438.1\| putative membrane protein [Escherichia coli O157:H7 str. EC4042], gi... gi\|208814892, gi... - gi\|208814892\|ref\|ZP_03256071.1\| putative membrane protein [Escherichia coli O157:H7 str. EC4045], gi... gi\|168758916, gi... - gi\|189354353\|gb\|EDU72772.1\| putative membrane protein [Escherichia coli O157:H7 str. EC4401], gi\|168... gi\|74311517, gi\|... - gi\|74311517\|ref\|YP_309936.1\| hypothetical protein SSON_0964 [Shigella sonnei Ss046], gi\|73854994\|gb\|... gi\|189001334, gi... - gi\|189001334\|gb\|EDU70320.1\| putative membrane protein [Escherichia coli O157:H7 str. EC4076], gi\|168... gi\|168777451, gi... - gi\|187767322\|gb\|EDU31166.1\| putative membrane protein [Escherichia coli O157:H7 str. EC4196], gi\|168... gi\|189359576, gi... - gi\|189359576\|gb\|EDU77995.1\| putative membrane protein [Escherichia coli O157:H7 str. EC4486], gi\|168... gi\|189364955, gi... - gi\|189364955\|gb\|EDU83371.1\| putative membrane protein [Escherichia coli O157:H7 str. EC4501], gi\|168...	394.0	[0..1]	[720..1]
gi\|82776251, gi\|... - gi\|82776251\|ref\|YP_402600.1\| hypothetical protein SDY_0935 [Shigella dysenteriae Sd197], gi\|81240399...	394.0	[0..1]	[720..1]
gi\|81246127, gi\|... - gi\|82544716\|ref\|YP_408663.1\| hypothetical protein SBO_2271 [Shigella boydii Sb227], gi\|81246127\|gb\|A... gi\|187734165, gi... - gi\|75175479\|ref\|ZP_00695699.1\| COG1289: Predicted membrane protein [Shigella boydii BS512], gi\|18773...	393.0	[0..1]	[720..1]
gi\|110804976, gi... - gi\|110804976\|ref\|YP_688496.1\| hypothetical protein SFV_0970 [Shigella flexneri 5 str. 8401], gi\|1106...	393.0	[0..1]	[720..1]
gi\|110342742, gi... - gi\|110641150\|ref\|YP_668880.1\| membrane protein YccS [Escherichia coli 536], gi\|110342742\|gb\|ABG68979... gi\|190905105, gi... - gi\|75235733\|ref\|ZP_00719900.1\| COG1289: Predicted membrane protein [Escherichia coli F11], gi\|191174...	392.0	[0..1]	[720..1]

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Predicted Domain #1

Region A:
Residues: [1-163]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFMLSPLLK RYTWNSAWLY YARIFIALCG TTAFPWWLGD VKLTIPLTLG MVAAALTDLD  60
   61 DRLAGRLRNL IITLFCFFIA SASVELLFPW PWLFAIGLTL STSGFILLGG LGQRYATIAF 120
  121 GALLIAIYTM LGTSLYEHWY QQPMYLLAGA VWYNVLTLIG HLL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [164-720]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FPVRPLQDNL ARCYEQLARY LELKSRMFDP DIEDQSQAPL YDLALANGLL MATLNQTKLS  60
   61 LLTRLRGDRG QRGTRRTLHY YFVAQDIHER ASSSHIQYQT LREHFRHSDV LFRFQRLMSM 120
  121 QGQACQQLSR CILLRQPYQH DPHFERAFTH IDAALERMRD NGAPADLLKT LGFLLNNLRA 180
  181 IDAQLATIES EQAQALPHNN DENELADDSP HGLSDIWLRL SRHFTPESAL FRHAVRMSLV 240
  241 LCFGYAIIQI TGMHHGYWIL LTSLFVCQPN YNATRHRLKL RIIGTLVGIA IGIPVLWFVP 300
  301 SLEGQLVLLV ITGVLFFAFR NVQYAHATMF ITLLVLLCFN LLGEGFEVAL PRVIDTLIGC 360
  361 AIAWAAVSYI WPDWQFRNLP RMLERATEAN CRYLDAILEQ YHQGRDNRLA YRIARRDAHN 420
  421 RDAELASVVS NMSSEPNVTP QIREAAFRLL CLNHTFTSYI SALGAHREQL TNPEILAFLD 480
  481 DAVCYVDDAL HHQPADEERV NEALASLKQR MQQLEPRADS KEPLVVQQVG LLIALLPEIG 540
  541 RLQRQITQVP QETPVSA

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.0
Match:	1hciA
Description:	alpha-actinin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.905633128746365	bayes_pls_golite062009
protein binding	0.618744687122036	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: