YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30258198, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	907 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30258198, gi|....

Description	E-value	Query Range	Subject Range
gi\|42738611, gi\|... - gi\|42782685\|ref\|NP_979932.1\| aconitate hydratase [Bacillus cereus ATCC 10987], gi\|42738611\|gb\|AAS425...	0.0	[1..907]	[1..907]
gi\|152975991, gi... - gi\|89203354\|ref\|ZP_01182029.1\| Aconitate hydratase 1 [Bacillus cereus subsp. cytotoxis NVH 391-98], ...	0.0	[1..907]	[1..907]
gi\|218160324, gi... - gi\|218232367\|ref\|YP_002368428.1\| aconitate hydratase 1 [Bacillus cereus B4264], gi\|218160324\|gb\|ACK6... gi\|47555376, gi\|... - gi\|47567898\|ref\|ZP_00238605.1\| aconitate hydratase 1 [Bacillus cereus G9241], gi\|47555376\|gb\|EAL1372...	0.0	[1..907]	[1..907]
gi\|30021715, gi\|... - gi\|30021715\|ref\|NP_833346.1\| aconitate hydratase [Bacillus cereus ATCC 14579], gi\|29897270\|gb\|AAP105...	0.0	[1..907]	[1..907]
gi\|163941221, gi... - gi\|89208420\|ref\|ZP_01186928.1\| Aconitate hydratase 1 [Bacillus weihenstephanensis KBAB4], gi\|8915364...	0.0	[1..907]	[1..907]
ACON_BACSU - Aconitate hydratase OS=Bacillus subtilis GN=citB PE=1 SV=4 ACNA_BACSU - Aconitate hydratase A OS=Bacillus subtilis (strain 168) GN=citB PE=1 SV=4 gi\|221323205 - gi\|221323205\|ref\|ZP_03604499.1\| aconitate hydratase [Bacillus subtilis subsp. subtilis str. SMY] gi\|221318931 - gi\|221318931\|ref\|ZP_03600225.1\| aconitate hydratase [Bacillus subtilis subsp. subtilis str. JH642] gi\|221314009 - gi\|221314009\|ref\|ZP_03595814.1\| aconitate hydratase [Bacillus subtilis subsp. subtilis str. NCIB 361...	0.0	[2..903]	[8..909]
gi\|22777364, gi\|... - gi\|23099136\|ref\|NP_692602.1\| aconitate hydratase [Oceanobacillus iheyensis HTE831], gi\|22777364\|dbj\|...	0.0	[1..901]	[1..902]
gi\|163119466, gi... - gi\|52785801\|ref\|YP_091630.1\| aconitate hydratase [Bacillus licheniformis ATCC 14580], gi\|52348303\|gb...	0.0	[2..902]	[8..908]
gi\|114540150, gi... - gi\|114705365\|ref\|ZP_01438273.1\| aconitate hydratase [Fulvimarina pelagi HTCC2506], gi\|114540150\|gb\|E...	0.0	[1..901]	[33..953]

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Predicted Domain #1

Region A:
Residues: [1-907]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKHNPFQSR ATFEVDGKTY HYYDLKALEN AGVGNVSQLP YSVKVLLESV LRQVDGRVIT  60
   61 EEHVTNLAKW GTKDVQDIDV PFKPSRVILQ DFTGVPAVVD LASLRKAMAD MGGDPDKINP 120
  121 EITVDLVIDH SVQVDRAGTA DALAFNMDLE FKRNEERYKF LSWAQKSFDN YRAVPPATGI 180
  181 VHQVNLEYLA PVVHAVKNAE GDLVAYPDSL VGTDSHTTMI NGIGVLGWGV GGIEAEAGML 240
  241 GQPSYFPVPE VIGVKLTGTL PSGTTATDVA LKVTQVLRQK GVVGKFVEFF GNGLKSMPLA 300
  301 DRATISNMAP EYGATCGFFP IDEISLEYLR LTGRDEEQIR VVEEYCKANG LFYTADSKDP 360
  361 IYTDLVEIDL NTIESNLSGP KRPQDLIPLS DMKDAFHKAV VAPVGTQGLG FNEQEFDKEV 420
  421 KVTLEDKEVT MKTGAIAIAA ITSCTNTSNP YVLIGAGLVA KKAIEKGLKV PEYVKTSLAP 480
  481 GSKVVTEYLD KSGLTTYLDQ LGFQTVGYGC TTCIGNSGPL APELEEAIAA NDLLVTSVLS 540
  541 GNRNFEGRIH PLVKANYLAS PPLVVAYALA GTVDIDLKND EIGKDANGNA VYFNDIWPSA 600
  601 KEIEDVVQSV VTSELFKKEY AQVFNSNERW NEIQTSNEAL YTWDNDSTYI QNPPFFEGLS 660
  661 KEPGEVETLS GLRVVGKFGD SVTTDHISPA GSIGKHTPAG RYLLENGVQP VDFNSYGSRR 720
  721 GNHEVMMRGT FANIRIKNQI APGTEGGYTT YWPTGEVTSI YDAAMKYKED GTGLLVVAGK 780
  781 DYGMGSSRDW AAKGTNLLGI KAVIAESFER IHRSNLVLMG VLPLQFKDGE SAETLGLVGN 840
  841 ESFEIQIDKT VRPRDLVKVV ATDLDGNEKQ FEVVARFDSE VEIDYYRHGG ILQMVLREKI 900
  901 EESKVSN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	2b3xA
Description:	Structure of an orthorhombic crystal form of human cytosolic aconitase (IRP1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
3-isopropylmalate dehydratase activity	11.6597692115322	bayes_pls_golite062009
aconitate hydratase activity	5.86356477922338	bayes_pls_golite062009
structural constituent of ribosome	5.49717480487827	bayes_pls_golite062009
structural molecule activity	5.20352686802457	bayes_pls_golite062009
catalytic activity	2.4040324437254	bayes_pls_golite062009
mRNA binding	2.2758554402042	bayes_pls_golite062009
nucleic acid binding	2.25736437672211	bayes_pls_golite062009
carbon-oxygen lyase activity	2.08349115784849	bayes_pls_golite062009
hydro-lyase activity	2.04845291489052	bayes_pls_golite062009
lyase activity	2.0080619912194	bayes_pls_golite062009
RNA binding	2.00311670878109	bayes_pls_golite062009
metal cluster binding	1.70706327499066	bayes_pls_golite062009
iron-sulfur cluster binding	1.70706327499066	bayes_pls_golite062009
binding	1.67914740974449	bayes_pls_golite062009
DNA binding	1.6436451615422	bayes_pls_golite062009
iron-responsive element binding	1.1980380564483	bayes_pls_golite062009
iron ion binding	1.12961684198784	bayes_pls_golite062009
4 iron, 4 sulfur cluster binding	1.11810757572823	bayes_pls_golite062009
transition metal ion binding	0.342428816025605	bayes_pls_golite062009
protein binding	0.232638130896339	bayes_pls_golite062009
cation binding	0.0272064751959212	bayes_pls_golite062009
metal ion binding	0.0272064751959212	bayes_pls_golite062009
ion binding	0.0228992031160024	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: