YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30264192, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	332 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30264192, gi|....

Description	E-value	Query Range	Subject Range
BIOB_BACCN - Biotin synthase OS=Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98) GN=bio...	3.0E-66	[1..332]	[1..332]
gi\|229168861, gi... - gi\|229168861\|ref\|ZP_04296579.1\| Biotin synthase [Bacillus cereus AH621], gi\|228614591\|gb\|EEK71698.1\|... BIOB_BACWK - Biotin synthase OS=Bacillus weihenstephanensis (strain KBAB4) GN=bioB PE=3 SV=1 gi\|228747920, gi... - gi\|229013327\|ref\|ZP_04170467.1\| Biotin synthase [Bacillus mycoides DSM 2048], gi\|228747920\|gb\|EEL977... gi\|229134925, gi... - gi\|229134925\|ref\|ZP_04263732.1\| Biotin synthase [Bacillus cereus BDRD-ST196], gi\|228648600\|gb\|EEL046... gi\|229061789, gi... - gi\|229061789\|ref\|ZP_04199122.1\| Biotin synthase [Bacillus cereus AH603], gi\|228717535\|gb\|EEL69199.1\|...	8.0E-66	[1..332]	[1..332]
gi\|85693260, gi\|... - gi\|85712880\|ref\|ZP_01043921.1\| Biotin synthase [Idiomarina baltica OS145], gi\|85693260\|gb\|EAQ31217.1...	1.0E-65	[16..330]	[6..321]
BIOB_BACCR - Biotin synthase OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 ...	4.0E-65	[1..332]	[1..332]
gi\|228849782, gi... - gi\|228909947\|ref\|ZP_04073768.1\| Biotin synthase [Bacillus thuringiensis IBL 200], gi\|228849782\|gb\|EE... gi\|228902626, gi... - gi\|228902626\|ref\|ZP_04066777.1\| Biotin synthase [Bacillus thuringiensis IBL 4222], gi\|228857067\|gb\|E... gi\|228960383, gi... - gi\|228960383\|ref\|ZP_04122035.1\| Biotin synthase [Bacillus thuringiensis serovar pakistani str. T1300... gi\|228805332, gi... - gi\|228954400\|ref\|ZP_04116426.1\| Biotin synthase [Bacillus thuringiensis serovar kurstaki str. T03a00... gi\|229071621, gi... - gi\|229071621\|ref\|ZP_04204839.1\| Biotin synthase [Bacillus cereus F65185], gi\|228711557\|gb\|EEL63514.1... gi\|228967153, gi... - gi\|228967153\|ref\|ZP_04128189.1\| Biotin synthase [Bacillus thuringiensis serovar sotto str. T04001], ... gi\|229129396, gi... - gi\|229129396\|ref\|ZP_04258367.1\| Biotin synthase [Bacillus cereus BDRD-Cer4], gi\|228654001\|gb\|EEL0986... BIOB_BACC2 - Biotin synthase OS=Bacillus cereus (strain G9842) GN=bioB PE=3 SV=1 gi\|228671972, gi... - gi\|229111590\|ref\|ZP_04241141.1\| Biotin synthase [Bacillus cereus Rock1-15], gi\|228671972\|gb\|EEL27265... gi\|228603143, gi... - gi\|229180396\|ref\|ZP_04307739.1\| Biotin synthase [Bacillus cereus 172560W], gi\|228603143\|gb\|EEK60621.... gi\|228631279, gi... - gi\|229152317\|ref\|ZP_04280510.1\| Biotin synthase [Bacillus cereus m1550], gi\|228631279\|gb\|EEK87915.1\|... gi\|228591108, gi... - gi\|229192328\|ref\|ZP_04319292.1\| Biotin synthase [Bacillus cereus ATCC 10876], gi\|228591108\|gb\|EEK489... gi\|75759242, gi\|... - gi\|75759242\|ref\|ZP_00739342.1\| Biotin synthase [Bacillus thuringiensis serovar israelensis ATCC 3564...	5.0E-65	[1..332]	[1..332]
BIOB_BACC1 - Biotin synthase OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=bioB PE=3 SV=1	9.0E-65	[1..332]	[1..332]
gi\|228625657, gi... - gi\|229157700\|ref\|ZP_04285775.1\| Biotin synthase [Bacillus cereus ATCC 4342], gi\|228625657\|gb\|EEK8240... gi\|47568175, gi\|... - gi\|47568175\|ref\|ZP_00238879.1\| biotin synthase [Bacillus cereus G9241], gi\|47555165\|gb\|EAL13512.1\| b...	1.0E-64	[1..332]	[1..332]
gi\|42543471, gi\|... - gi\|42543471\|pdb\|1R30\|B Chain B, The Crystal Structure Of Biotin Synthase, An S- Adenosylmethionine-D...	5.0E-64	[22..332]	[29..340]
gi\|49086966 - gi\|49086966\|gb\|AAT51401.1\| PA0500 [synthetic construct]	6.0E-64	[17..331]	[7..322]
BIOB_SHIB3 - Biotin synthase OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=bioB PE=3 SV=1 BIOB_SHIBS - Biotin synthase OS=Shigella boydii serotype 4 (strain Sb227) GN=bioB PE=3 SV=1	8.0E-64	[22..332]	[6..317]

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Predicted Domain #1

Region A:
Residues: [1-332]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQVQTKRDW KKLAYDVVEE KMITKEDAIA ILEADDTEVL EIMNAAYIIR HHYFGKKVKL  60
   61 NMIINTKSGL CPEDCGYCSQ SIISEAPIDK YAWLTQEKIV EGAHEAIRRK AGTYCIVASG 120
  121 RRPTDKEVNH VIGAVKEIRE TTDLKICCCL GFLNEDQAGR LAEAGVHRYN HNLNTHANNY 180
  181 ESICSTHTYD DRVDTVQKAK QAGISPCSGA IFGMGETIEE RAEIAFELQR IDADSIPCNF 240
  241 LVAVKGTPLE GQKELTPVEC LKVLAMMRFV NPTKEIRISG GREINLRSVQ PIGLFAANSI 300
  301 FVGDYLTTAG QEPTADWGMI EDLGFEIEEC AL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	65.522879
Match:	1r30A
Description:	The Crystal Structure of Biotin Synthase, an S-Adenosylmethionine-Dependent Radical Enzyme
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
biotin synthase activity	5.10405272282485	bayes_pls_golite062009
radical SAM enzyme activity	4.95763122788913	bayes_pls_golite062009
sulfurtransferase activity	2.53050234490351	bayes_pls_golite062009
transferase activity, transferring sulfur-containing groups	2.01614319399424	bayes_pls_golite062009
catalytic activity	1.85375915825216	bayes_pls_golite062009
coproporphyrinogen oxidase activity	1.27516985221578	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	0.604275066192139	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	0.0323089631112699	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: