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View Structure Prediction Details

Protein: FBpp0311724, inv...
Organism: Drosophila melanogaster
Length: 576 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0311724, inv....

Description E-value Query
Range
Subject
Range
gi|8139, gi|85030 - pir||A26628 homeotic protein Invected - fruit fly (Drosophila melanogaster), gi|8139|emb|CAA28885.1...
199.0 [0..1] [576..1]

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Predicted Domain #1
Region A:
Residues: [1-107]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTLASTRPP PLKLTIPSLE EAEDHAQERR AGGGGQEVGK MHPDCLPLPL VQPGNSPQVR  60
   61 EEEEDEQTEC EEQLNIEDEE VEEEHDLDLE DPASCCSENS VLSVGQE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [108-282]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSEAAQAALS AQAQARQRLL ISQIYRPSAF SSTATTVLPP SEGPPFSPED LLQLPPSTGT  60
   61 FQEEFLRKSQ LYAEELMKQQ MHLMAAARVN ALTAAAAGKQ LQMAMAAAAV ATVPSGQDAL 120
  121 AQLTATALGL GPGGAVHPHQ QLLLQRDQVH HHHHMQNHLN NNENLHERAL KFSID

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [283-473]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NILKADFGSR LPKIGALSGN IGGGSVSGSS TGSSKNSGNT NGNRSPLKAP KKSGKPLNLA  60
   61 QSNAAANSSL SFSSSLANIC SNSNDSNSTA TSSSTTNTSG APVDLVKSPP PAAGAGATGA 120
  121 SGKSGEDSGT PIVWPAWVYC TRYSDRPSSG RSPRARKPKK PATSSSAAGG GGGGVEKGEA 180
  181 ADGGGVPEDK R

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [474-576]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRTAFSGTQL ARLKHEFNEN RYLTEKRRQQ LSGELGLNEA QIKIWFQNKR AKLKKSSGTK  60
   61 NPLALQLMAQ GLYNHSTIPL TREEEELQEL QEAASAAAAK EPC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.522879
Match: 1homA
Description: DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.13863038737912 bayes_pls_golite062009
DNA binding 4.66369707598026 bayes_pls_golite062009
nucleic acid binding 4.51452285155271 bayes_pls_golite062009
transcription factor activity 4.06706589695599 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.16896789933192 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
sequence-specific DNA binding 2.41271657675151 bayes_pls_golite062009
transcription repressor activity 1.91962622287073 bayes_pls_golite062009
transcription activator activity 1.77700860354597 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.73068440195944 bayes_pls_golite062009
chromatin binding 1.68956710349366 bayes_pls_golite062009
transcription factor binding 1.40653841901929 bayes_pls_golite062009
transcription cofactor activity 0.84983974758882 bayes_pls_golite062009
protein binding 0.830419844171551 bayes_pls_golite062009
transcription corepressor activity 0.25931464844298 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle