YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|50513267, gi\|...
Organism:	Archaeoglobus fulgidus
Length:	322 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|50513267, gi|....

Description	E-value	Query Range	Subject Range
gi\|55670452, gi\|... - gi\|55670452\|pdb\|1VLL\|B Chain B, Crystal Structure Of Alanine Dehydrogenase (Af1665) From Archaeoglob...	329.0	[0..1]	[322..13]
gi\|21226199, gi\|... - gi\|21226199\|ref\|NP_632121.1\| alanine dehydrogenase [Methanosarcina mazei Go1], gi\|20904431\|gb\|AAM297...	307.0	[0..1]	[320..9]
gi\|20092068, gi\|... - gi\|20092068\|ref\|NP_618143.1\| alanine dehydrogenase [Methanosarcina acetivorans C2A], gi\|19917283\|gb\|...	307.0	[0..1]	[320..1]
gi\|73670641, gi\|... - gi\|73670641\|ref\|YP_306656.1\| alanine dehydrogenase [Methanosarcina barkeri str. Fusaro], gi\|72397803...	306.0	[0..1]	[320..1]
gi\|91773253, gi\|... - gi\|91773253\|ref\|YP_565945.1\| alanine dehydrogenase [Methanococcoides burtonii DSM 6242], gi\|91712268...	297.0	[0..1]	[320..1]
gi\|88928826, gi\|... - gi\|88952152\|ref\|ZP_01154624.1\| Ornithine cyclodeaminase/mu-crystallin [Methanosaeta thermophila PT],...	296.0	[0..1]	[318..137]
gi\|7482770 - pir\|\|C69066 ornithine cyclodeaminase - Methanobacterium thermoautotrophicum (strain Delta H) gi\|15679492, gi\|... - gi\|2622612\|gb\|AAB85970.1\| ornithine cyclodeaminase [Methanothermobacter thermautotrophicus str. Delt...	282.0	[0..2]	[319..12]
gi\|73748085, gi\|... - gi\|73748085\|ref\|YP_307324.1\| ornithine cyclodeaminase [Dehalococcoides sp. CBDB1], gi\|73659801\|emb\|C...	281.0	[0..1]	[321..1]
gi\|147668887, gi... - gi\|88932856\|ref\|ZP_01138538.1\| Ornithine cyclodeaminase [Dehalococcoides sp. BAV1], gi\|88914709\|gb\|E...	281.0	[0..1]	[319..1]
gi\|147920078, gi... - gi\|147920078\|ref\|YP_686163.1\| ornithine cyclodeaminase [uncultured methanogenic archaeon RC-I], gi\|1...	272.0	[0..2]	[319..1]

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Predicted Domain #1

Region A:
Residues: [1-322]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METLILTQEE VESLISMDEA MNAVEEAFRL YALGKAQMPP KVYLEFEKGD LRAMPAHLMG  60
   61 YAGLKWVNSH PGNPDKGLPT VMALMILNSP ETGFPLAVMD ATYTTSLRTG AAGGIAAKYL 120
  121 ARKNSSVFGF IGCGTQAYFQ LEALRRVFDI GEVKAYDVRE KAAKKFVSYC EDRGISASVQ 180
  181 PAEEASRCDV LVTTTPSRKP VVKAEWVEEG THINAIGADG PGKQELDVEI LKKAKIVVDD 240
  241 LEQAKHGGEI NVAVSKGVIG VEDVHATIGE VIAGLKDGRE SDEEITIFDS TGLAIQDVAV 300
  301 AKVVYENALS KNVGSKIKFF RI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	90.045757
Match:	1vllA
Description:	Crystal structure of alanine dehydrogenase (AF1665) from Archaeoglobus fulgidus at 2.80 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.79741889688267	bayes_pls_golite062009
oxidoreductase activity	1.69771604880532	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1.68807048598905	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors	1.4310711328288	bayes_pls_golite062009
nucleic acid binding	1.01867974073274	bayes_pls_golite062009
DNA binding	0.984833962235604	bayes_pls_golite062009
transcription regulator activity	0.918090951258227	bayes_pls_golite062009
steroid dehydrogenase activity	0.568360595866292	bayes_pls_golite062009
retinol dehydrogenase activity	0.530688665000667	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	0.418775403210681	bayes_pls_golite062009
pyrroline-5-carboxylate reductase activity	0.395118481369763	bayes_pls_golite062009
binding	0.343109880193463	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.32207755075663	bayes_pls_golite062009
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.281209522528842	bayes_pls_golite062009
transcription repressor activity	0.252352977981399	bayes_pls_golite062009
transcription factor activity	0.225193089386851	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: