YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30264067, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	512 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30264067, gi|....

Description	E-value	Query Range	Subject Range
gi\|238783835, gi... - gi\|77958961\|ref\|ZP_00822986.1\| COG0248: Exopolyphosphatase [Yersinia bercovieri ATCC 43970], gi\|2387...	0.0	[2..509]	[8..508]
gi\|77629846, gi\|... - gi\|77629846\|ref\|ZP_00792432.1\| COG0248: Exopolyphosphatase [Yersinia pseudotuberculosis IP 31758], g... gi\|165937131, gi... - gi\|89104917\|ref\|ZP_01177447.1\| COG0248: Exopolyphosphatase [Yersinia pestis biovar Orientalis str. I... gi\|165926016, gi... - gi\|165926016\|ref\|ZP_02221848.1\| exopolyphosphatase [Yersinia pestis biovar Orientalis str. F1991016]... gi\|165992796, gi... - gi\|166008414\|ref\|ZP_02229312.1\| exopolyphosphatase [Yersinia pestis biovar Antiqua str. E1979001], g... gi\|166206438, gi... - gi\|166212507\|ref\|ZP_02238542.1\| exopolyphosphatase [Yersinia pestis biovar Antiqua str. B42003004], ... gi\|166960759, gi... - gi\|167421270\|ref\|ZP_02313023.1\| exopolyphosphatase [Yersinia pestis biovar Orientalis str. MG05-1020... gi\|229681652, gi... - gi\|229901723\|ref\|ZP_04516845.1\| exopolyphosphatase [Yersinia pestis Nepal516], gi\|229681652\|gb\|EEO77... gi\|167056354, gi... - gi\|167424472\|ref\|ZP_02316225.1\| exopolyphosphatase [Yersinia pestis biovar Mediaevalis str. K1973002... Q668D7\|Q668D7_YERPS - Putative exopolyphosphatase - Yersinia pseudotuberculosis gi\|167467165 - gi\|167467165\|ref\|ZP_02331869.1\| exopolyphosphatase [Yersinia pestis FV-1] gi\|149365300, gi... - gi\|149365300\|ref\|ZP_01887335.1\| exopolyphosphatase [Yersinia pestis CA88-4125], gi\|149291713\|gb\|EDM4... gi\|169750119, gi... - gi\|170023585\|ref\|YP_001720090.1\| exopolyphosphatase [Yersinia pseudotuberculosis YPIII], gi\|16975011... gi\|145599461, gi... - gi\|145599461\|ref\|YP_001163537.1\| exopolyphosphatase [Yersinia pestis Pestoides F], gi\|145211157\|gb\|A... gi\|186896210, gi... - gi\|186896210\|ref\|YP_001873322.1\| exopolyphosphatase [Yersinia pseudotuberculosis PB1/+], gi\|18669923... gi\|229694778, gi... - gi\|229838412\|ref\|ZP_04458571.1\| exopolyphosphatase [Yersinia pestis biovar Orientalis str. PEXU2], g... gi\|229701555, gi... - gi\|229895400\|ref\|ZP_04510572.1\| exopolyphosphatase [Yersinia pestis Pestoides A], gi\|229701555\|gb\|EE... gi\|25290375 - pir\|\|AF0345 probable exopolyphosphatase (EC 3.6.1.11) [imported] - Yersinia pestis (strain CO92) gi\|229898979, gi... - gi\|229898979\|ref\|ZP_04514123.1\| exopolyphosphatase [Yersinia pestis biovar Orientalis str. India 195... gi\|45437342, gi\|... - gi\|45442477\|ref\|NP_994016.1\| exopolyphosphatase [Yersinia pestis biovar Microtus str. 91001], gi\|454... gi\|22125295, gi\|... - gi\|22125295\|ref\|NP_668718.1\| exopolyphosphatase [Yersinia pestis KIM], gi\|21958171\|gb\|AAM84969.1\|AE0... gi\|218929900, gi... - gi\|218929900\|ref\|YP_002347775.1\| exopolyphosphatase [Yersinia pestis CO92], gi\|16123032\|ref\|NP_40634... gi\|51597119, gi\|... - gi\|51597119\|ref\|YP_071310.1\| exopolyphosphatase [Yersinia pseudotuberculosis IP 32953], gi\|51590401\|...	0.0	[2..509]	[7..507]
gi\|167051313, gi... - gi\|167398809\|ref\|ZP_02304333.1\| exopolyphosphatase [Yersinia pestis biovar Antiqua str. UG05-0454], ... gi\|108780181, gi... - gi\|108808268\|ref\|YP_652184.1\| exopolyphosphatase [Yersinia pestis Antiqua], gi\|108780181\|gb\|ABG14239...	0.0	[2..509]	[7..507]
gi\|113474131, gi... - gi\|71675228\|ref\|ZP_00672973.1\| Guanosine-5'-triphosphate,3'-diphosphate diphosphatase [Trichodesmium...	0.0	[7..510]	[19..539]
gi\|187731393, gi... - gi\|75178107\|ref\|ZP_00698166.1\| COG0248: Exopolyphosphatase [Shigella boydii BS512], gi\|187731393\|ref... gi\|82544949, gi\|... - gi\|82544949\|ref\|YP_408896.1\| exopolyphosphatase [Shigella boydii Sb227], gi\|81246360\|gb\|ABB67068.1\| ...	0.0	[2..510]	[6..507]
gi\|162352033, gi... - gi\|77636354\|ref\|ZP_00798429.1\| COG0248: Exopolyphosphatase [Yersinia pestis Angola], gi\|162419218\|re...	0.0	[2..509]	[7..507]
gi\|82777881, gi\|... - gi\|82777881\|ref\|YP_404230.1\| exopolyphosphatase [Shigella dysenteriae Sd197], gi\|81242029\|gb\|ABB6273...	0.0	[2..510]	[6..507]
gi\|15832618, gi\|... - gi\|15832618\|ref\|NP_311391.1\| exopolyphosphatase [Escherichia coli O157:H7 str. Sakai], gi\|13362834\|d... gi\|89109308, gi\|... - gi\|89109308\|ref\|AP_003088.1\| exopolyphosphatase [Escherichia coli str. K-12 substr. W3110], gi\|18055... gi\|91211823, gi\|... - gi\|91211823\|ref\|YP_541809.1\| exopolyphosphatase [Escherichia coli UTI89], gi\|91073397\|gb\|ABE08278.1\|... PPX_ECOLI - Exopolyphosphatase (EC 3.6.1.11) (ExopolyPase) (Metaphosphatase) - Escherichia coli PPX_ECOL6 - Exopolyphosphatase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=ppx PE=3 SV=2 gi\|188017022, gi... - gi\|188017022\|gb\|EDU55144.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4113], gi\|168748440\|... PPX_ECO57 - Exopolyphosphatase OS=Escherichia coli O157:H7 GN=ppx PE=1 SV=2 gi\|168756273, gi... - gi\|189356554\|gb\|EDU74973.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4401], gi\|168756273\|... EG11403 - exopolyphosphatase / Exopolyphosphatase; inhibited by pppGpp and ppGpp, also has guanosine pentaphos... gi\|168773585, gi... - gi\|187770642\|gb\|EDU34486.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4196], gi\|168773585\|... gi\|12516890, gi\|... - gi\|15803025\|ref\|NP_289055.1\| exopolyphosphatase [Escherichia coli O157:H7 EDL933], gi\|12516890\|gb\|AA... gi\|189003181, gi... - gi\|189003181\|gb\|EDU72167.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4076], gi\|168778467\|... gi\|189372364, gi... - gi\|189372364\|gb\|EDU90780.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC869], gi\|168787847\|r... gi\|209398375, gi... - gi\|209398375\|ref\|YP_002271971.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4115], gi\|20915... gi\|209913238, gi... - gi\|209919979\|ref\|YP_002294063.1\| exopolyphosphatase [Escherichia coli SE11], gi\|209913238\|dbj\|BAG783... gi\|217319566, gi... - gi\|217327199\|ref\|ZP_03443282.1\| exopolyphosphatase [Escherichia coli O157:H7 str. TW14588], gi\|21731... EG11403 - exopolyphosphatase / Exopolyphosphatase; inhibited by pppGpp and ppGpp, also has guanosine pentaphos... gi\|218559426, gi... - gi\|218559426\|ref\|YP_002392339.1\| exopolyphosphatase [Escherichia coli S88], gi\|218366195\|emb\|CAR0394... gi\|218696129, gi... - gi\|218696129\|ref\|YP_002403796.1\| exopolyphosphatase [Escherichia coli 55989], gi\|218352861\|emb\|CAU98... gi\|254794447, gi... - gi\|254794447\|ref\|YP_003079284.1\| exopolyphosphatase [Escherichia coli O157:H7 str. TW14359], gi\|2545... gi\|218706001, gi... - gi\|218706001\|ref\|YP_002413520.1\| exopolyphosphatase [Escherichia coli UMN026], gi\|218433098\|emb\|CAR1... gi\|253974377, gi... - gi\|254162476\|ref\|YP_003045584.1\| exopolyphosphatase [Escherichia coli B str. REL606], gi\|253974377\|g... gi\|253323650, gi... - gi\|254289237\|ref\|YP_003054985.1\| exopolyphosphatase [Escherichia coli BL21(DE3)], gi\|253978544\|gb\|AC... gi\|251785827, gi... - gi\|251785827\|ref\|YP_003000131.1\| hypothetical protein B21_02356 [Escherichia coli BL21], gi\|24237810... gi\|168798872, gi... - gi\|189378553\|gb\|EDU96969.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC508], gi\|168798872\|r... gi\|238861059, gi... - gi\|238901667\|ref\|YP_002927463.1\| exopolyphosphatase [Escherichia coli BW2952], gi\|238861059\|gb\|ACR63... gi\|169754142, gi... - gi\|170019214\|ref\|YP_001724168.1\| exopolyphosphatase [Escherichia coli ATCC 8739], gi\|169754142\|gb\|AC... gi\|226901374, gi... - gi\|237705008\|ref\|ZP_04535489.1\| exopolyphosphatase [Escherichia sp. 3_2_53FAA], gi\|226901374\|gb\|EEH8... gi\|74313028, gi\|... - gi\|74313028\|ref\|YP_311447.1\| exopolyphosphatase [Shigella sonnei Ss046], gi\|73856505\|gb\|AAZ89212.1\| ... gi\|169889947, gi... - gi\|170082112\|ref\|YP_001731432.1\| exopolyphosphatase [Escherichia coli str. K-12 substr. DH10B], gi\|1... gi\|227835882, gi... - gi\|227887532\|ref\|ZP_04005337.1\| exopolyphosphatase [Escherichia coli 83972], gi\|227835882\|gb\|EEJ4634... PPX_ECOL6 - Exopolyphosphatase OS=Escherichia coli O6 GN=ppx PE=3 SV=2 gi\|170682766, gi... - gi\|170682766\|ref\|YP_001744686.1\| exopolyphosphatase [Escherichia coli SMS-3-5], gi\|170520484\|gb\|ACB1... gi\|195936644 - gi\|195936644\|ref\|ZP_03082026.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4024] gi\|208728650, gi... - gi\|208808849\|ref\|ZP_03251186.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4206], gi\|208728... gi\|208814562, gi... - gi\|208814562\|ref\|ZP_03255891.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4045], gi\|208735... gi\|208739064, gi... - gi\|208818941\|ref\|ZP_03259261.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4042], gi\|208739... gi\|194423464, gi... - gi\|83586849\|ref\|ZP_00925480.1\| COG0248: Exopolyphosphatase [Escherichia coli 101-1], gi\|194437658\|re... gi\|193064767, gi... - gi\|75257309\|ref\|ZP_00728833.1\| COG0248: Exopolyphosphatase [Escherichia coli E22], gi\|193064767\|ref\|... gi\|188493752, gi... - gi\|75515843\|ref\|ZP_00737978.1\| COG0248: Exopolyphosphatase [Escherichia coli 53638], gi\|188493752\|re... gi\|157078836, gi... - gi\|75187254\|ref\|ZP_00700521.1\| COG0248: Exopolyphosphatase [Escherichia coli E24377A], gi\|157156806\|... gi\|75211469, gi\|... - gi\|75211469\|ref\|ZP_00711559.1\| COG0248: Exopolyphosphatase [Escherichia coli B171], gi\|194427254\|ref... gi\|117624686, gi... - gi\|117624686\|ref\|YP_853599.1\| exopolyphosphatase [Escherichia coli APEC O1], gi\|115513810\|gb\|ABJ0188...	0.0	[2..510]	[6..507]
gi\|24113830, gi\|... - gi\|24113830\|ref\|NP_708340.1\| exopolyphosphatase [Shigella flexneri 2a str. 301], gi\|24052920\|gb\|AAN4... gi\|30042131, gi\|... - gi\|30063876\|ref\|NP_838047.1\| exopolyphosphatase [Shigella flexneri 2a str. 2457T], gi\|30042131\|gb\|AA...	0.0	[2..510]	[6..507]
gi\|83570721, gi\|... - gi\|83570721\|ref\|ZP_00922164.1\| COG0248: Exopolyphosphatase [Shigella dysenteriae 1012], gi\|194432122...	0.0	[2..510]	[6..507]

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Predicted Domain #1

Region A:
Residues: [1-512]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKEILKQQYA IIDIGSNTMR LVIYEKQNGG FYKEIENTKV VARLRNYLVD GVLIEEGIEV  60
   61 LLQTLFQFQE STRFHQLHHV LCVATATIRQ AKNQEEIKKL VEGQTDFTLR VLSEYEEARY 120
  121 GYLAVMNSTS FSEGITVDIG GGSTEVTYFR NREILEYHSF PFGALSLKQQ FIKDDIPTEE 180
  181 ELEKLQTYLE YQFRTLPWLI DKKLPLIAIG GSARNLVKIH QNLICYPIAG VHLYKMKEED 240
  241 IKNVKEELEA LSFIELQKLE GLAKDRADTI VPAVEVFHTL VNVIEAPAFV LSRKGLREGV 300
  301 FYEELTKDLG ISYYPNVVEE SLYLLSHEYE MDMEFVMQLI KHGRLICQQL EETGLISMSV 360
  361 EDWEVFHQAA KVFNIGKYID EEASRLHTFY LLANKTIDGM MHKERVRLAL IASYKSKMLF 420
  421 KQHLSPFEGW FDKNEQKKIR LLGAVLQFSA ALNIRQRSLV ESISITESKE GLTFEIVCEQ 480
  481 SALAEKVQAE KQKKQLERVL KTNIILLFKL KN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	136.0
Match:	1u6zA
Description:	Structure of an E. coli Exopolyphosphatase: Insight into the processive hydrolysis of polyphosphate and its regulation
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
kinase activity	1.66953112101574	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	1.48325454573133	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.42990549365307	bayes_pls_golite062009
GTP diphosphokinase activity	1.20625646347886	bayes_pls_golite062009
guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity	1.1479499593037	bayes_pls_golite062009
diphosphoric monoester hydrolase activity	1.1479499593037	bayes_pls_golite062009
transferase activity	0.770095506614066	bayes_pls_golite062009
polyphosphate kinase activity	0.7290773631638	bayes_pls_golite062009
catalytic activity	0.666924658593345	bayes_pls_golite062009
binding	0.554867574854209	bayes_pls_golite062009
phosphoric diester hydrolase activity	0.431648413805265	bayes_pls_golite062009
cyclic-nucleotide phosphodiesterase activity	0.380631072103095	bayes_pls_golite062009
protein binding	0.298844891785753	bayes_pls_golite062009
3',5'-cyclic-nucleotide phosphodiesterase activity	0.238185114534071	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: