YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30264529, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	429 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30264529, gi|....

Description	E-value	Query Range	Subject Range
GSA_HISS2 - Glutamate-1-semialdehyde 2,1-aminomutase OS=Histophilus somni (strain 2336) GN=hemL PE=3 SV=1	0.0	[4..429]	[1..428]
GSA2_BACLD - Glutamate-1-semialdehyde 2,1-aminomutase 2 OS=Bacillus licheniformis (strain ATCC 14580 / DSM 13 / J...	0.0	[1..427]	[1..427]
GSA_HAES1 - Glutamate-1-semialdehyde 2,1-aminomutase OS=Haemophilus somnus (strain 129Pt) GN=hemL PE=3 SV=1	0.0	[4..427]	[1..426]
GSA2_BACHD - Glutamate-1-semialdehyde 2,1-aminomutase 2 OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 /... GSA2_BACHD, GSA_... - Glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) (GSA) (Glutamate-1-semialdehyde aminotransfera...	0.0	[1..428]	[1..428]
gi\|221319996 - gi\|221319996\|ref\|ZP_03601290.1\| glutamate-1-semialdehyde aminotransferase [Bacillus subtilis subsp. ... gi\|221324278 - gi\|221324278\|ref\|ZP_03605572.1\| glutamate-1-semialdehyde aminotransferase [Bacillus subtilis subsp. ... GSA_BACSU - Glutamate-1-semialdehyde 2,1-aminomutase OS=Bacillus subtilis GN=hemL PE=1 SV=1 GSA_BACSU - Glutamate-1-semialdehyde 2,1-aminomutase OS=Bacillus subtilis (strain 168) GN=hemL PE=1 SV=1 gi\|221315077 - gi\|221315077\|ref\|ZP_03596882.1\| glutamate-1-semialdehyde aminotransferase [Bacillus subtilis subsp. ...	0.0	[1..427]	[1..427]
GSA2_GEOKA - Glutamate-1-semialdehyde 2,1-aminomutase 2 OS=Geobacillus kaustophilus GN=hemL2 PE=3 SV=1 GSA2_GEOKA - Glutamate-1-semialdehyde 2,1-aminomutase 2 OS=Geobacillus kaustophilus (strain HTA426) GN=hemL2 PE=3...	0.0	[1..428]	[1..428]
GSA_MANSM - Glutamate-1-semialdehyde 2,1-aminomutase OS=Mannheimia succiniciproducens (strain MBEL55E) GN=hemL P...	0.0	[4..417]	[1..416]
GSA_PASMU - Glutamate-1-semialdehyde 2,1-aminomutase OS=Pasteurella multocida (strain Pm70) GN=hemL PE=3 SV=1 GSA_PASMU - Glutamate-1-semialdehyde 2,1-aminomutase OS=Pasteurella multocida GN=hemL PE=3 SV=1	0.0	[4..428]	[1..427]
GSA2_EXIS2 - Glutamate-1-semialdehyde 2,1-aminomutase 2 OS=Exiguobacterium sibiricum (strain DSM 17290 / JCM 1349...	0.0	[2..428]	[5..431]
gi\|89098942, gi\|... - gi\|89098942\|ref\|ZP_01171822.1\| glutamate-1-semialdehyde aminotransferase [Bacillus sp. NRRL B-14911]...	0.0	[1..428]	[1..428]

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Predicted Domain #1

Region A:
Residues: [1-429]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRKFDKSIAA FEEAQDLMPG GVNSPVRAFK SVGMNPLFME RGKGSKVYDI DGNEYIDYVL  60
   61 SWGPLIHGHA NDRVVEALKA VAERGTSFGA PTEIENKLAK LVIERVPSIE IVRMVNSGTE 120
  121 ATMSALRLAR GYTGRNKILK FIGCYHGHGD SLLIKAGSGV ATLGLPDSPG VPEGVAKNTI 180
  181 TVAYNDLESV KYAFEQFGDD IACVIVEPVA GNMGVVPPQP GFLEGLREVT EQNGALLIFD 240
  241 EVMTGFRVAY NCGQGYYGVT PDLTCLGKVI GGGLPVGAYG GKAEIMRQVA PSGPIYQAGT 300
  301 LSGNPLAMAA GYETLVQLTP ESYVEFERKA EMLEAGLRKA AEKHGIPHHI NRAGSMIGIF 360
  361 FTDEPVINYD AAKSSNLQFF AAYYREMVEQ GVFLPPSQFE GLFLSTVHSD ADIEATIAAA 420
  421 EIAMSKLKA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	106.0
Match:	2gsaA
Description:	Glutamate-1-semialdehyde aminomutase (aminotransferase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
4-aminobutyrate transaminase activity	3.63797881096751	bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity	3.359406422625	bayes_pls_golite062009
catalytic activity	2.29878871754893	bayes_pls_golite062009
5-aminolevulinate synthase activity	1.85905571238884	bayes_pls_golite062009
adenosylmethionine-8-amino-7-oxononanoate transaminase activity	1.74778109525713	bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity	1.63055151623667	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	1.63055151623667	bayes_pls_golite062009
N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	1.4383564662931	bayes_pls_golite062009
glutamate decarboxylase activity	1.34215658716536	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	1.28316822767388	bayes_pls_golite062009
transaminase activity	1.24990480711889	bayes_pls_golite062009
transferase activity, transferring acyl groups	1.19150094103499	bayes_pls_golite062009
succinate-semialdehyde dehydrogenase binding	0.78144409237642	bayes_pls_golite062009
transferase activity	0.737426388870721	bayes_pls_golite062009
carbon-sulfur lyase activity	0.698312655247044	bayes_pls_golite062009
intramolecular transferase activity, transferring amino groups	0.659071155545801	bayes_pls_golite062009
N-succinyltransferase activity	0.52897097514616	bayes_pls_golite062009
ornithine-oxo-acid transaminase activity	0.311107335626334	bayes_pls_golite062009
N-acyltransferase activity	0.2609065149092	bayes_pls_golite062009
kynureninase activity	0.242752584041108	bayes_pls_golite062009
cystathionine beta-lyase activity	0.15938456446406	bayes_pls_golite062009
sulfurtransferase activity	0.0450490929307473	bayes_pls_golite062009
nucleic acid binding	0.013097682076602	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: