YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30263264, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	512 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30263264, gi|....

Description	E-value	Query Range	Subject Range
gi\|42738292, gi\|... - gi\|42782367\|ref\|NP_979614.1\| thiol-activated cytolysin [Bacillus cereus ATCC 10987], gi\|42738292\|gb\|...	0.0	[1..512]	[1..512]
gi\|52142243, gi\|... - gi\|52142243\|ref\|YP_084586.1\| perfringolysin O, thiol-activated cytolysin [Bacillus cereus E33L], gi\|...	0.0	[1..512]	[1..512]
gi\|49481660, gi\|... - gi\|49481660\|ref\|YP_037419.1\| perfringolysin O, thiol-activated cytolysin [Bacillus thuringiensis ser...	0.0	[1..512]	[1..512]
gi\|21401229, gi\|... - gi\|65320595\|ref\|ZP_00393554.1\| hypothetical protein Bant_01004014 [Bacillus anthracis str. A2012], r...	0.0	[1..512]	[1..512]
gi\|89204987, gi\|... - gi\|89204987\|ref\|ZP_01183560.1\| Thiol-activated cytolysin [Bacillus weihenstephanensis KBAB4], gi\|891...	0.0	[1..512]	[1..512]
gi\|229130344, gi... - gi\|229130344\|ref\|ZP_04259302.1\| Alveolysin [Bacillus cereus BDRD-Cer4], gi\|228653043\|gb\|EEL08923.1\| ... gi\|229049774, gi... - gi\|229049774\|ref\|ZP_04194331.1\| Alveolysin [Bacillus cereus AH676], gi\|228722687\|gb\|EEL74075.1\| Alve... gi\|29898698, gi\|... - gi\|30023138\|ref\|NP_834769.1\| perfringolysin O precursor [Bacillus cereus ATCC 14579], gi\|29898698\|gb...	0.0	[1..512]	[1..512]
gi\|74492448, gi\|... - gi\|75760060\|ref\|ZP_00740124.1\| Perfringolysin O precursor [Bacillus thuringiensis serovar israelensi... gi\|228856023, gi... - gi\|228903594\|ref\|ZP_04067715.1\| Alveolysin [Bacillus thuringiensis IBL 4222], gi\|228856023\|gb\|EEN005...	0.0	[1..512]	[1..512]
gi\|62550724 - gi\|62550724\|gb\|AAX88798.1\| cereolysin O [Bacillus cereus]	0.0	[4..512]	[1..509]
gi\|62550722 - gi\|62550722\|gb\|AAX88797.1\| cereolysin O [Bacillus thuringiensis]	0.0	[4..512]	[1..509]
gi\|47564431, gi\|... - gi\|47564431\|ref\|ZP_00235476.1\| perfringolysin O precursor [Bacillus cereus G9241], gi\|47558583\|gb\|EA...	0.0	[1..512]	[1..512]

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Predicted Domain #1

Region A:
Residues: [1-512]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIFLNIKKNT KRRKFLACLL VSLCTIHYSS ISFAETQAGN ATGAIKNASD INTGIANLKY  60
   61 DSRDILAVNG DKVESFIPKE SINSNGKFVV VEREKKSLTT SPVDILIIDS VVNRTYPGAV 120
  121 QLANKAFADN QPSLLVAKRK PLNISIDLPG MRKENTITVQ NPTYGNVAGA VDDLVSTWNE 180
  181 KYSTTHTLPA RMQYTESMVY SKSQIASALN VNAKYLDNSL NIDFNAVANG EKKVMVAAYK 240
  241 QIFYTVSAEL PNNPSDLFDN SVTFDELTRK GVSNSAPPVM VSNVAYGRTV YVKLETTSKS 300
  301 KDVQAAFKAL LKNNSVETSG QYKDIFEEST FTAVVLGGDA KEHNKVVTKD FNEIRNIIKD 360
  361 NAELSFKNPA YPISYTSTFL KDNATAAVHN NTDYIETTTT EYSSAKMTLD HYGAYVAQFD 420
  421 VSWDEFTFDQ NGKEVLTHKT WEGSGKDKTA HYSTVIPLPP NSKNIKIVAR ECTGLAWEWW 480
  481 RTIINEQNVP LTNEIKVSIG GTTLYPTATI SH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1pfoA
Description:	PERFRINGOLYSIN O
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
steroid binding	2.37454025040029	bayes_pls_golite062009
lipid binding	1.32936018471889	bayes_pls_golite062009
binding	1.14120897465863	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: