YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30262191, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	562 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30262191, gi|....

Description	E-value	Query Range	Subject Range
gi\|81177190, gi\|... - gi\|81177190\|ref\|ZP_00876053.1\| Arginyl-tRNA synthetase, class Ic [Streptococcus suis 89/1591], gi\|80...	0.0	[1..562]	[1..562]
SYR_LACLA - Arginine--tRNA ligase OS=Lactococcus lactis subsp. lactis (strain IL1403) GN=argS PE=3 SV=1 SYR_LACLA - Arginyl-tRNA synthetase OS=Lactococcus lactis subsp. lactis GN=argS PE=3 SV=1	0.0	[1..562]	[1..564]
SYR_PEDPA - Arginine--tRNA ligase OS=Pediococcus pentosaceus (strain ATCC 25745 / 183-1w) GN=argS PE=3 SV=1	0.0	[1..562]	[1..562]
SYR_STRP2 - Arginine--tRNA ligase OS=Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) GN=argS PE=3 S... SYR_STRZJ - Arginine--tRNA ligase OS=Streptococcus pneumoniae (strain JJA) GN=argS PE=3 SV=1 gi\|25293288 - pir\|\|G98107 arginine-tRNA ligase (EC 6.1.1.19) [imported] - Streptococcus pneumoniae (strain R6) SYR_STRPJ - Arginine--tRNA ligase OS=Streptococcus pneumoniae (strain ATCC 700669 / Spain 23F-1) GN=argS PE=3 SV... gi\|183572255, gi... - gi\|183572255\|gb\|EDT92783.1\| arginyl-tRNA synthetase [Streptococcus pneumoniae SP195], gi\|168489140\|r... gi\|148992079, gi... - gi\|148992079\|ref\|ZP_01821853.1\| arginyl-tRNA synthetase [Streptococcus pneumoniae SP9-BS68], gi\|1479... gi\|183570152, gi... - gi\|183570152\|gb\|EDT90680.1\| arginyl-tRNA synthetase [Streptococcus pneumoniae CDC1087-00], gi\|168486... gi\|148989896, gi... - gi\|148989896\|ref\|ZP_01821179.1\| arginyl-tRNA synthetase [Streptococcus pneumoniae SP6-BS73], gi\|1479... gi\|183575862, gi... - gi\|183575862\|gb\|EDT96390.1\| arginyl-tRNA synthetase [Streptococcus pneumoniae CDC3059-06], gi\|168494... gi\|183574045, gi... - gi\|183574045\|gb\|EDT94573.1\| arginyl-tRNA synthetase [Streptococcus pneumoniae CDC0288-04], gi\|168491... SYR_STRR6 - Arginine--tRNA ligase OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) GN=argS PE=3 SV=1	0.0	[1..562]	[1..563]
SYR_LACLS - Arginine--tRNA ligase OS=Lactococcus lactis subsp. cremoris (strain SK11) GN=argS PE=3 SV=1	0.0	[1..562]	[1..564]
SYR_STRTD - Arginine--tRNA ligase OS=Streptococcus thermophilus (strain ATCC BAA-491 / LMD-9) GN=argS PE=3 SV=1 SYR_STRT1 - Arginine--tRNA ligase OS=Streptococcus thermophilus (strain CNRZ 1066) GN=argS PE=3 SV=1 gi\|55738023 - gb\|AAV61664.1\| arginyl-tRNA synthetase [Streptococcus thermophilus CNRZ1066]	0.0	[1..562]	[1..563]
SYR1_BACCZ - Arginine--tRNA ligase 1 OS=Bacillus cereus (strain ZK / E33L) GN=argS1 PE=3 SV=1	0.0	[1..562]	[1..562]
SYR_STRPN - Arginine--tRNA ligase OS=Streptococcus pneumoniae GN=argS PE=1 SV=2 SYR_STRPN - Arginine--tRNA ligase OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) GN=argS P...	0.0	[1..562]	[1..563]
gi\|9295534 - gi\|9295534\|gb\|AAF86984.1\|AF282249_3 ArgS [Lactococcus lactis subsp. lactis] SYR_LACLM - Arginine--tRNA ligase OS=Lactococcus lactis subsp. cremoris (strain MG1363) GN=argS PE=3 SV=1	0.0	[1..562]	[1..564]

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Predicted Domain #1

Region A:
Residues: [1-562]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDYKTQFAES LSNIFTNELT QQQILDLIET PKQDEFGDAA FPCFSLAKQY KKSPAIIAKE  60
   61 VAEKLSDPFF TKVEAVGPYV NVFFNRDTVS DAVLKTILAE KEEYGKNYFG CEKTVVIDYS 120
  121 SPNIAKPFSM GHLRSTMIGN SLKHIAEKCG YEVVGINYIG DWGTQFGKLI TAYKKWGNEA 180
  181 VVKEDPIREL FKLYVQFHEE VKDDEELEEE GRAWFKKLEE GDEEAVELWN WFRHESLKEF 240
  241 SRIYELLGVE FTNFQGEAFY NNLMEDFIGI LEEHDLLEES EGALVVNLEE EGMPPCLIRK 300
  301 SDGATIYATR DLTAALYRQN TFGFDKALYV VGPEQSLHFN QFFTVLKKLG YTWVDGMEHV 360
  361 PFGFILKDGK KMSTRKGRVI LLEEVLEEAI ELAKQNIEEK NPNLKQKEEV AKQVGAGAVI 420
  421 FHDLKNERMH NIEFSLENML KFEGETGPYV QYTHARACSI LRKESVEFET CTFALKDDHS 480
  481 WSVVKLLNKF PQVIEIAFNK NEPSVISKYV LDVAQSFNKY YGNVRILEES EEKDSRLALV 540
  541 YAVTVVLKEG LRLLGVEAPE EM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	77.69897
Match:	1bs2A
Description:	Arginyl-tRNA synthetase (ArgRS); Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming aminoacyl-tRNA and related compounds	7.16276509815667	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	7.16276509815667	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	7.13957775963187	bayes_pls_golite062009
ligase activity	6.11211476973434	bayes_pls_golite062009
arginine-tRNA ligase activity	5.72854650987135	bayes_pls_golite062009
isoleucine-tRNA ligase activity	3.76808520367507	bayes_pls_golite062009
glutamate-tRNA ligase activity	2.63681738794687	bayes_pls_golite062009
methionine-tRNA ligase activity	2.56893064485672	bayes_pls_golite062009
catalytic activity	2.37674226834122	bayes_pls_golite062009
tyrosine-tRNA ligase activity	1.88984817882585	bayes_pls_golite062009
tryptophan-tRNA ligase activity	1.14187887833901	bayes_pls_golite062009
nucleic acid binding	1.03251266786448	bayes_pls_golite062009
binding	0.914435503471172	bayes_pls_golite062009
cysteine-tRNA ligase activity	0.844943947059557	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.625793556381714	bayes_pls_golite062009
nucleotidyltransferase activity	0.564359271862248	bayes_pls_golite062009
glutamine-tRNA ligase activity	0.118292082006187	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: