YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|39998036, gi\|...
Organism:	Geobacter sulfurreducens PCA
Length:	248 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|39998036, gi|....

Description	E-value	Query Range	Subject Range
gi\|28204363, gi\|... - gi\|28211920\|ref\|NP_782864.1\| putative activator of (R) -2-hydroxyglutaryl-CoA dehydratase [Clostridi...	263.0	[0..2]	[245..321]
gi\|53685995, gi\|... - gi\|68205821\|ref\|ZP_00558019.1\| CoA enzyme activase [Desulfitobacterium hafniense DCB-2], gi\|68170311... gi\|89334489, gi\|... - gi\|89895041\|ref\|YP_518528.1\| hypothetical protein DSY2295 [Desulfitobacterium hafniense Y51], gi\|893...	262.0	[0..2]	[244..7]
gi\|91200821 - gi\|91200821\|emb\|CAJ73875.1\| hypothetical protein [Candidatus Kuenenia stuttgartiensis]	260.0	[0..2]	[244..3]
gi\|25496065 - pir\|\|A97196 hypothetical protein CAC2401 [imported] - Clostridium acetobutylicum gi\|15895667, gi\|... - gi\|15895667\|ref\|NP_349016.1\| 2-hydroxyglutaryl-CoA dehydratase activator [Clostridium acetobutylicum...	259.0	[0..2]	[245..322]
gi\|20807576 - gi\|20807576\|ref\|NP_622747.1\| Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase doma... gi\|20807576, gi\|... - gi\|20807576\|ref\|NP_622747.1\| 2-hydroxyglutaryl-CoA dehydratase activator [Thermoanaerobacter tengcon...	258.0	[0..2]	[243..286]
gi\|78045224, gi\|... - gi\|78045224\|ref\|YP_360030.1\| putative CoA dehydratase subunit/(R)-2-hydroxyglutaryl-CoA dehydratase ...	257.0	[0..2]	[244..294]
gi\|110682433, gi... - gi\|110801932\|ref\|YP_698537.1\| CoA-substrate-specific enzyme activase, putative [Clostridium perfring...	257.0	[0..2]	[246..319]
gi\|114843949, gi... - gi\|167040529\|ref\|YP_001663514.1\| putative CoA-substrate-specific enzyme activase [Thermoanaerobacter... gi\|76796296, gi\|... - gi\|76796296\|ref\|ZP_00778661.1\| CoA enzyme activase [Thermoanaerobacter ethanolicus ATCC 33223], gi\|7... gi\|241883189, gi... - gi\|241904432\|ref\|ZP_04789128.1\| CoA-substrate-specific enzyme activase [Thermoanaerobacter brockii s... gi\|242230063, gi... - gi\|242258415\|ref\|ZP_04803222.1\| CoA-substrate-specific enzyme activase [Thermoanaerobacter sp. X513]...	257.0	[0..2]	[243..285]
gi\|18144856, gi\|... - gi\|18310177\|ref\|NP_562111.1\| hypothetical protein CPE1195 [Clostridium perfringens str. 13], gi\|1814...	256.0	[0..2]	[246..348]
gi\|27886099, gi\|... - gi\|34764126\|ref\|ZP_00144999.1\| Activator of (R)-2-hydroxyglutaryl-CoA dehydratase [Fusobacterium nuc...	256.0	[0..2]	[247..61]

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Predicted Domain #1

Region A:
Residues: [1-248]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLIGIDLGSR SIKLAAVKDG ILAESLVVES GFAPHDQAAL LLARFNARRV VSTGYGRHLA  60
   61 QRHFAGEIIT EIKAHALGAR HADPSCETVL DVGGQDSKVI NLDGAGRVKN FQMNDKCAAG 120
  121 TGRFLEIMAA TLGYTLAEFG EAALAAREGN AIGSMCAVFA ESEVISLKNR GTPPEAIARS 180
  181 VHLAIVDRLA AMLNKAGHGR RLVFSGGAAR NRALVGLLEE RLGVRFTVPE RPEIMGALGA 240
  241 ALHAGTLD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	62.0
Match:	1huxA
Description:	Hydroxyglutaryl-CoA dehydratase component A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
kinase activity	1.55847742629362	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	1.41326067130808	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.32934175997085	bayes_pls_golite062009
acetate kinase activity	1.02147739254786	bayes_pls_golite062009
transferase activity	0.752605732921866	bayes_pls_golite062009
catalytic activity	0.666924658593345	bayes_pls_golite062009
protein binding	0.375225171889093	bayes_pls_golite062009
carbohydrate kinase activity	0.21579608499336	bayes_pls_golite062009
binding	0.186094217739223	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: