YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|39996719, gi\|...
Organism:	Geobacter sulfurreducens PCA
Length:	119 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|39996719, gi|....

Description	E-value	Query Range	Subject Range
gi\|98660701 - gi\|98660701\|dbj\|GAA02123.1\| unnamed protein product [Pelotomaculum thermopropionicum SI]	161.0	[0..2]	[119..105]
gi\|89204059, gi\|... - gi\|89204059\|ref\|ZP_01182638.1\| Response regulator receiver:Transcriptional regulatory protein, C-ter...	158.0	[0..1]	[117..1]
gi\|191637826, gi... - gi\|191637826\|ref\|YP_001986992.1\| Putative response regulator [Lactobacillus casei BL23], gi\|19071212... gi\|116104591, gi... - gi\|62514699\|ref\|ZP_00386196.1\| COG0745: Response regulators consisting of a CheY-like receiver domai... gi\|239631190, gi... - gi\|239631190\|ref\|ZP_04674221.1\| DNA-binding response regulator [Lactobacillus paracasei subsp. parac... gi\|227535595, gi... - gi\|227535595\|ref\|ZP_03965644.1\| response regulator [Lactobacillus paracasei subsp. paracasei ATCC 25...	155.0	[0..1]	[119..1]
gi\|3236110 - gi\|3236110\|emb\|CAA04532.1\| arcA [Lactococcus lactis]	154.0	[0..1]	[118..1]
gi\|25300862 - pir\|\|E86674 two-component system regulator llrC [imported] - Lactococcus lactis subsp. lactis (strai... gi\|62462808, gi\|... - gi\|62462808\|ref\|ZP_00382181.1\| COG0745: Response regulators consisting of a CheY-like receiver domai... gi\|12483717 - gi\|12483717\|gb\|AAG53732.1\|AF178425_2 RrC [Lactococcus lactis] gi\|15672379, gi\|... - gi\|15672379\|ref\|NP_266553.1\| two-component system regulator [Lactococcus lactis subsp. lactis Il1403... gi\|124492089, gi... - gi\|125623281\|ref\|YP_001031764.1\| two-component system regulator [Lactococcus lactis subsp. cremoris ...	153.0	[0..1]	[118..1]
gi\|15616589, gi\|... - gi\|15616589\|ref\|NP_244895.1\| two-component response regulator [Bacillus halodurans C-125], gi\|101766... gi\|25300883 - pir\|\|C84153 two-component response regulator BH4027 [imported] - Bacillus halodurans (strain C-125)	153.0	[0..2]	[118..4]
gi\|110801119, gi... - gi\|110801119\|ref\|YP_695076.1\| DNA-binding response regulator [Clostridium perfringens ATCC 13124], g...	153.0	[0..2]	[119..4]
gi\|66780532, gi\|... - gi\|94972307\|ref\|YP_594347.1\| two component transcriptional regulator [Deinococcus geothermalis DSM 1...	153.0	[0..1]	[118..22]
gi\|116333280, gi... - gi\|116333280\|ref\|YP_794807.1\| DNA-binding response regulator [Lactobacillus brevis ATCC 367], gi\|116...	153.0	[0..1]	[119..1]
gi\|29375768, gi\|... - gi\|29375768\|ref\|NP_814922.1\| DNA-binding response regulator VicR [Enterococcus faecalis V583], gi\|29... gi\|229308653, gi... - gi\|229546129\|ref\|ZP_04434854.1\| DNA-binding response regulator protein [Enterococcus faecalis TX1332... gi\|227177886, gi... - gi\|227552977\|ref\|ZP_03983026.1\| DNA-binding response regulator [Enterococcus faecalis HH22], gi\|2271... gi\|227074125, gi... - gi\|227518447\|ref\|ZP_03948496.1\| DNA-binding response regulator [Enterococcus faecalis TX0104], gi\|22... gi\|238857001, gi... - gi\|238857001\|ref\|ZP_04647257.1\| transcriptional regulatory protein [Enterococcus faecalis TUSoD Ef11... gi\|229550318, gi... - gi\|229550318\|ref\|ZP_04439043.1\| DNA-binding response regulator [Enterococcus faecalis ATCC 29200], g...	153.0	[0..1]	[118..1]

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Predicted Domain #1

Region A:
Residues: [1-119]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKVLIVDDS ISVARQLDKI LSESGEFQVV GHGKNGMEAI RMHQTEHPDI ICMDMNMPGM  60
   61 DGLTALRTLV ALDKNIKVVM VTSLGGVGDK FTEALRLGAR TVISKPFEAD NVLKILREL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.69897
Match:	1mvoA
Description:	PhoP receiver domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
two-component response regulator activity	7.02872640261738	bayes_pls_golite062009
transcription regulator activity	5.23016166796951	bayes_pls_golite062009
signal transducer activity	4.51666042720644	bayes_pls_golite062009
molecular transducer activity	4.51666042720644	bayes_pls_golite062009
DNA binding	2.75354350283069	bayes_pls_golite062009
nucleic acid binding	2.67056525675208	bayes_pls_golite062009
protein histidine kinase activity	2.35011582062573	bayes_pls_golite062009
two-component sensor activity	2.32303301074957	bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor	2.28838869071567	bayes_pls_golite062009
transcription factor activity	2.12579037300919	bayes_pls_golite062009
binding	1.22427537074115	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: