YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|39982552, gi\|...
Organism:	Geobacter sulfurreducens PCA
Length:	215 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|39982552, gi|....

Description	E-value	Query Range	Subject Range
gi\|98660701 - gi\|98660701\|dbj\|GAA02123.1\| unnamed protein product [Pelotomaculum thermopropionicum SI]	194.0	[0..2]	[211..105]
gi\|53688577 - gi\|53688577\|ref\|ZP_00110736.2\| COG2197: Response regulator containing a CheY-like receiver domain an...	194.0	[0..1]	[206..1]
gi\|196252895, gi... - gi\|196252895\|ref\|ZP_03151542.1\| two component transcriptional regulator, LuxR family [Clostridium th... gi\|67873312, gi\|... - gi\|67873312\|ref\|ZP_00503591.1\| regulatory protein, LuxR:Response regulator receiver [Clostridium the...	194.0	[0..2]	[209..4]
gi\|51855517, gi\|... - gi\|51891828\|ref\|YP_074519.1\| two-component response regulator [Symbiobacterium thermophilum IAM 1486...	193.0	[0..3]	[211..5]
gi\|7471836 - pir\|\|E75450 DNA-binding response regulator - Deinococcus radiodurans (strain R1) gi\|6458715, gi\|1... - gi\|6458715\|gb\|AAF10563.1\|AE001951_3 DNA-binding response regulator [Deinococcus radiodurans R1], gi\|...	192.0	[0..2]	[215..26]
gi\|28209958, gi\|... - gi\|28209958\|ref\|NP_780902.1\| transcriptional regulatory protein [Clostridium tetani E88], gi\|2820239...	191.0	[0..2]	[211..24]
gi\|83589824, gi\|... - gi\|83589824\|ref\|YP_429833.1\| two component LuxR family transcriptional regulator [Moorella thermoace...	190.0	[0..2]	[211..7]
gi\|47555239, gi\|... - gi\|47568085\|ref\|ZP_00238790.1\| DNA-binding response regulator [Bacillus cereus G9241], gi\|47555239\|g... gi\|228675259, gi... - gi\|229108243\|ref\|ZP_04237865.1\| DNA-binding response regulator [Bacillus cereus Rock1-15], gi\|228675... gi\|229042495, gi... - gi\|229042495\|ref\|ZP_04190240.1\| DNA-binding response regulator [Bacillus cereus AH676], gi\|228726848... gi\|229194950, gi... - gi\|229194950\|ref\|ZP_04321731.1\| DNA-binding response regulator [Bacillus cereus m1293], gi\|228588518...	189.0	[0..1]	[214..1]
gi\|42780487, gi\|... - gi\|42780487\|ref\|NP_977734.1\| DNA-binding response regulator [Bacillus cereus ATCC 10987], gi\|4273640... gi\|222095033, gi... - gi\|222095033\|ref\|YP_002529093.1\| response regulator [Bacillus cereus Q1], gi\|221239091\|gb\|ACM11801.1... gi\|217068126, gi... - gi\|217958874\|ref\|YP_002337422.1\| DNA-binding response regulator [Bacillus cereus AH187], gi\|21706812... gi\|206977570, gi... - gi\|206977570\|ref\|ZP_03238464.1\| DNA-binding response regulator [Bacillus cereus H3081.97], gi\|206744...	189.0	[0..2]	[211..4]

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Predicted Domain #1

Region A:
Residues: [1-215]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRVLLVDDH RIVLEGLRAL VSEHSDLEVV GVACDGATAI ELTRQLRPDV VVMDITMPGM  60
   61 NGIEATRRIV AEFPRTRVLI LSMESERRFV LEVLKTGAHG YLLKDCSQDE LVSAIRHVAG 120
  121 GEPYLGPRIT EMIIRAYMER IPDDTLLTHT LLSLREREVL QLIAAGKSTK EIAFAFGVSL 180
  181 KTIETQRHSI MKKLNLYSVA ELTKYAIREG LTPLR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.69897
Match:	1a04A
Description:	Nitrate/nitrite response regulator (NarL); Nitrate/nitrite response regulator (NarL), receiver domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
two-component response regulator activity	7.02872640261738	bayes_pls_golite062009
transcription regulator activity	5.23016166796951	bayes_pls_golite062009
signal transducer activity	4.51666042720644	bayes_pls_golite062009
molecular transducer activity	4.51666042720644	bayes_pls_golite062009
DNA binding	2.75354350283069	bayes_pls_golite062009
nucleic acid binding	2.67056525675208	bayes_pls_golite062009
protein histidine kinase activity	2.35011582062573	bayes_pls_golite062009
two-component sensor activity	2.32303301074957	bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor	2.28838869071567	bayes_pls_golite062009
transcription factor activity	2.12579037300919	bayes_pls_golite062009
binding	1.22427537074115	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: