YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|39982322, gi\|...
Organism:	Geobacter sulfurreducens PCA
Length:	224 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|39982322, gi|....

Description	E-value	Query Range	Subject Range
gi\|98660701 - gi\|98660701\|dbj\|GAA02123.1\| unnamed protein product [Pelotomaculum thermopropionicum SI]	229.0	[0..2]	[223..106]
gi\|48860348, gi\|... - gi\|67873291\|ref\|ZP_00503570.1\| Response regulator receiver:Transcriptional regulatory protein, C ter...	224.0	[0..2]	[221..6]
gi\|82402957, gi\|... - gi\|82499061\|ref\|ZP_00884513.1\| Response regulator receiver [Caldicellulosiruptor saccharolyticus DSM...	222.0	[0..1]	[221..1]
gi\|42780487, gi\|... - gi\|42780487\|ref\|NP_977734.1\| DNA-binding response regulator [Bacillus cereus ATCC 10987], gi\|4273640... gi\|222095033, gi... - gi\|222095033\|ref\|YP_002529093.1\| response regulator [Bacillus cereus Q1], gi\|221239091\|gb\|ACM11801.1... gi\|217068126, gi... - gi\|217958874\|ref\|YP_002337422.1\| DNA-binding response regulator [Bacillus cereus AH187], gi\|21706812... gi\|206977570, gi... - gi\|206977570\|ref\|ZP_03238464.1\| DNA-binding response regulator [Bacillus cereus H3081.97], gi\|206744...	221.0	[0..2]	[221..5]
gi\|222053517, gi... - gi\|222053517\|ref\|YP_002535879.1\| two component transcriptional regulator, winged helix family [Geoba...	220.0	[0..1]	[224..1]
gi\|95928481, gi\|... - gi\|95928481\|ref\|ZP_01311228.1\| two component transcriptional regulator, winged helix family [Desulfu...	220.0	[0..1]	[223..1]
gi\|77996843, gi\|... - gi\|78044728\|ref\|YP_360866.1\| DNA-binding response regulator [Carboxydothermus hydrogenoformans Z-290...	220.0	[0..1]	[223..1]
gi\|47556738, gi\|... - gi\|47566185\|ref\|ZP_00237213.1\| two-component response regulator [Bacillus cereus G9241], gi\|47556738...	219.0	[0..2]	[221..5]
gi\|28209958, gi\|... - gi\|28209958\|ref\|NP_780902.1\| transcriptional regulatory protein [Clostridium tetani E88], gi\|2820239...	219.0	[0..2]	[221..25]

Back

Predicted Domain #1

Region A:
Residues: [1-224]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVLVVEDEK KVSSFIKRGL EEEKYEVDAA FNGEEGLKMA LDKGYDLIVL DVMLPKKDGL  60
   61 SVVRELRERK NSTPVLMLTA KDSVEDIVAG LDSGSDDYLT KPFAFAELLA RVRALVRRSE 120
  121 QDRGAEIRFA DLRLDPVTHK VWRKDKEIDL TAKEYSLLEY FMRNPNQVLT RTMIAEHVWD 180
  181 YTFDSFTNII DVYVNYLRKK IDRESDKKLI HTVRGVGYIL KEED

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.69897
Match:	1kgsA
Description:	PhoB; PhoB receiver domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
two-component response regulator activity	7.02872640261738	bayes_pls_golite062009
transcription regulator activity	5.23016166796951	bayes_pls_golite062009
signal transducer activity	4.51666042720644	bayes_pls_golite062009
molecular transducer activity	4.51666042720644	bayes_pls_golite062009
DNA binding	2.75354350283069	bayes_pls_golite062009
nucleic acid binding	2.67056525675208	bayes_pls_golite062009
protein histidine kinase activity	2.35011582062573	bayes_pls_golite062009
two-component sensor activity	2.32303301074957	bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor	2.28838869071567	bayes_pls_golite062009
transcription factor activity	2.12579037300919	bayes_pls_golite062009
binding	1.22427537074115	bayes_pls_golite062009
protein kinase activity	1.00737355751913	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.811771244977462	bayes_pls_golite062009
kinase activity	0.725824770559857	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.476057209677045	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: