YRC Public Data Repository - Protein Structure Prediction

Protein:	ATP6_COXBU
Organism:	Coxiella burnetii RSA 493
Length:	264 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ATP6_COXBU.

Description	E-value	Query Range	Subject Range
gi\|629605, gi\|515963 - pir\|\|S42658 H+-transporting two-sector ATPase (EC 3.6.3.14) protein 6 precursor - radish mitochondri...	186.0	[0..17]	[264..176]
ATP6_VIBAL - ATP synthase subunit a OS=Vibrio alginolyticus GN=atpB PE=3 SV=1 gi\|91226232, gi\|... - gi\|91226232\|ref\|ZP_01261072.1\| F0F1 ATP synthase subunit A [Vibrio alginolyticus 12G01], gi\|91189243... gi\|254229971, gi... - gi\|75855550\|ref\|ZP_00763198.1\| COG0356: F0F1-type ATP synthase, subunit a [Vibrio sp. Ex25], gi\|2542...	175.0	[0..4]	[263..5]
ATP6_COXBR - ATP synthase subunit a OS=Coxiella burnetii (strain RSA 331 / Henzerling II) GN=atpB PE=3 SV=1	175.0	[0..1]	[264..1]
gi\|149748126, gi... - gi\|153838503\|ref\|ZP_01991170.1\| ATP synthase a chain [Vibrio parahaemolyticus AQ3810], gi\|149748126\|... ATP6_VIBPA - ATP synthase subunit a OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=atpB PE=3 ... ATP6_VIBPA - ATP synthase subunit a OS=Vibrio parahaemolyticus GN=atpB PE=3 SV=1	175.0	[0..4]	[263..5]
ATP6_SALCH - ATP synthase subunit a OS=Salmonella choleraesuis (strain SC-B67) GN=atpB PE=3 SV=1 gi\|238913124 - gi\|238913124\|ref\|ZP_04656961.1\| F0F1 ATP synthase subunit A [Salmonella enterica subsp. enterica ser... ATP6_SALPA - ATP synthase subunit a OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=atpB PE=3 SV=1 ATP6_SALCH - ATP synthase subunit a OS=Salmonella choleraesuis GN=atpB PE=3 SV=1 ATP6_SALTY - ATP synthase subunit a OS=Salmonella typhimurium GN=atpB PE=3 SV=1 ATP6_SALA4 - ATP synthase subunit a OS=Salmonella agona (strain SL483) GN=atpB PE=3 SV=1 ATP6_SALSV - ATP synthase subunit a OS=Salmonella schwarzengrund (strain CVM19633) GN=atpB PE=3 SV=1 gi\|194458415, gi... - gi\|194472051\|ref\|ZP_03078035.1\| ATP synthase F0, A subunit [Salmonella enterica subsp. enterica sero... ATP6_SALHS - ATP synthase subunit a OS=Salmonella heidelberg (strain SL476) GN=atpB PE=3 SV=1 gi\|29143943, gi\|... - gi\|29143943\|ref\|NP_807285.1\| F0F1 ATP synthase subunit A [Salmonella enterica subsp. enterica serova... gi\|200388972, gi... - gi\|200388972\|ref\|ZP_03215584.1\| ATP synthase F0, A subunit [Salmonella enterica subsp. enterica sero... gi\|16762455 - gi\|16762455\|ref\|NP_458072.1\| F0F1 ATP synthase subunit A [Salmonella enterica subsp. enterica serova... ATP6_SALDC - ATP synthase subunit a OS=Salmonella dublin (strain CT_02021853) GN=atpB PE=3 SV=1 ATP6_SALTI - ATP synthase subunit a OS=Salmonella typhi GN=atpB PE=3 SV=1 ATP6_SALPK - ATP synthase subunit a OS=Salmonella paratyphi A (strain AKU_12601) GN=atpB PE=3 SV=1 ATP6_SALTY - ATP synthase subunit a OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=atpB PE=3 ... gi\|197265871, gi... - gi\|197265871\|ref\|ZP_03165945.1\| ATP synthase F0, A subunit [Salmonella enterica subsp. enterica sero... gi\|197287676, gi... - gi\|197287676\|gb\|EDY27067.1\| ATP synthase F0, A subunit [Salmonella enterica subsp. enterica serovar ... gi\|205331669, gi... - gi\|205331669\|gb\|EDZ18433.1\| ATP synthase F0, A subunit [Salmonella enterica subsp. enterica serovar ... gi\|205327323, gi... - gi\|205327323\|gb\|EDZ14087.1\| ATP synthase F0, A subunit [Salmonella enterica subsp. enterica serovar ... ATP6_SALPB - ATP synthase subunit a OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=atpB PE=3 SV=1 ATP6_SALNS - ATP synthase subunit a OS=Salmonella newport (strain SL254) GN=atpB PE=3 SV=1 gi\|168823136, gi... - gi\|205340561\|gb\|EDZ27325.1\| ATP synthase F0, A subunit [Salmonella enterica subsp. enterica serovar ... gi\|168464794, gi... - gi\|195632259\|gb\|EDX50743.1\| ATP synthase F0, A subunit [Salmonella enterica subsp. enterica serovar ... ATP6_SALPB - ATP synthase subunit a OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=atpB PE=3 SV=1 gi\|205348284, gi... - gi\|205348284\|gb\|EDZ34915.1\| ATP synthase F0, A subunit [Salmonella enterica subsp. enterica serovar ... gi\|81416159 - gi\|81416159\|sp\|Q7CPE3.1\|ATP6_SALTY RecName: Full=ATP synthase subunit a; AltName: Full=F-ATPase subu... ATP6_SALPA - ATP synthase subunit a OS=Salmonella paratyphi A GN=atpB PE=3 SV=1 gi\|75479642 - gi\|75479642\|sp\|Q57HX3.1\|ATP6_SALCH RecName: Full=ATP synthase subunit a; AltName: Full=F-ATPase subu... ATP6_SALPC - ATP synthase subunit a OS=Salmonella paratyphi C (strain RKS4594) GN=atpB PE=3 SV=1 gi\|81628043 - gi\|81628043\|sp\|Q8XGC2.1\|ATP6_SALTI RecName: Full=ATP synthase subunit a; AltName: Full=F-ATPase subu... gi\|213052664 - gi\|213052664\|ref\|ZP_03345542.1\| F0F1 ATP synthase subunit A [Salmonella enterica subsp. enterica ser... ATP6_SALEP - ATP synthase subunit a OS=Salmonella enteritidis PT4 (strain P125109) GN=atpB PE=3 SV=1 lcl\|NC_016856.1_... - [gene=atpB] [protein=F0F1 ATP synthase subunit A] [protein_id=YP_005240139.1] [location=complement(4... ATP6_SALG2 - ATP synthase subunit a OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=atpB PE=3 SV=1 gi\|204928835, gi... - gi\|204928835\|ref\|ZP_03220034.1\| ATP synthase F0, A subunit [Salmonella enterica subsp. enterica sero... gi\|214001330 - gi\|214001330\|ref\|ZP_03412065.1\| F0F1 ATP synthase subunit A [Salmonella enterica subsp. enterica ser... gi\|213649864 - gi\|213649864\|ref\|ZP_03379917.1\| F0F1 ATP synthase subunit A [Salmonella enterica subsp. enterica ser... gi\|213427464 - gi\|213427464\|ref\|ZP_03360214.1\| F0F1 ATP synthase subunit A [Salmonella enterica subsp. enterica ser... gi\|213418552 - gi\|213418552\|ref\|ZP_03351618.1\| F0F1 ATP synthase subunit A [Salmonella enterica subsp. enterica ser...	174.0	[0..2]	[264..1]
gi\|90581145, gi\|... - gi\|90581145\|ref\|ZP_01236944.1\| ATP synthase subunit A [Vibrio angustum S14], gi\|90437666\|gb\|EAS62858...	174.0	[0..4]	[263..5]
gi\|254847266, gi... - gi\|75829191\|ref\|ZP_00758503.1\| COG0356: F0F1-type ATP synthase, subunit a [Vibrio cholerae MO10], gi... ATP6_VIBC3 - ATP synthase subunit a OS=Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O39... gi\|116219392, gi... - gi\|75818738\|ref\|ZP_00748866.1\| COG0356: F0F1-type ATP synthase, subunit a [Vibrio cholerae V51], gi\|... gi\|121729381, gi... - gi\|75814914\|ref\|ZP_00745454.1\| COG0356: F0F1-type ATP synthase, subunit a [Vibrio cholerae V52], gi\|... gi\|121591533, gi... - gi\|121591533\|ref\|ZP_01678796.1\| ATP synthase F0, A subunit [Vibrio cholerae 2740-80], gi\|121546618\|g... gi\|124116207, gi... - gi\|153212981\|ref\|ZP_01948575.1\| ATP synthase F0, A subunit [Vibrio cholerae 1587], gi\|124116207\|gb\|E... gi\|153820049, gi... - gi\|153820049\|ref\|ZP_01972716.1\| ATP synthase F0, A subunit [Vibrio cholerae NCTC 8457], gi\|126509406... gi\|153821977, gi... - gi\|229508635\|ref\|ZP_04398130.1\| ATP synthase A chain [Vibrio cholerae B33], gi\|229354349\|gb\|EEO19277... ATP6_VIBCM - ATP synthase subunit a OS=Vibrio cholerae serotype O1 (strain M66-2) GN=atpB PE=3 SV=1 gi\|229508283, gi... - gi\|229508283\|ref\|ZP_04397787.1\| ATP synthase A chain [Vibrio cholerae BX 330286], gi\|229354556\|gb\|EE... gi\|229347063, gi... - gi\|229515963\|ref\|ZP_04405420.1\| ATP synthase A chain [Vibrio cholerae TMA 21], gi\|229347063\|gb\|EEO12... gi\|229517149, gi... - gi\|229517149\|ref\|ZP_04406595.1\| ATP synthase A chain [Vibrio cholerae RC9], gi\|229346212\|gb\|EEO11184... gi\|229342753, gi... - gi\|229520159\|ref\|ZP_04409586.1\| ATP synthase A chain [Vibrio cholerae TM 11079-80], gi\|229342753\|gb\|... gi\|229606557, gi... - gi\|229606557\|ref\|YP_002877205.1\| ATP synthase A chain [Vibrio cholerae MJ-1236], gi\|229369212\|gb\|ACQ... gi\|150422987, gi... - gi\|254291142\|ref\|ZP_04961939.1\| ATP synthase F0, A subunit [Vibrio cholerae AM-19226], gi\|197751562\|... ATP6_VIBCH - ATP synthase subunit a OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) GN=a... gi\|153827198, gi... - gi\|153827198\|ref\|ZP_01979865.1\| ATP synthase F0, A subunit [Vibrio cholerae MZO-2], gi\|149738921\|gb\|... ATP6_VIBCH - ATP synthase subunit a OS=Vibrio cholerae GN=atpB PE=3 SV=1	174.0	[0..4]	[263..5]
ATP61_ARATH - ATP synthase subunit a-1 OS=Arabidopsis thaliana GN=ATP6-1 PE=2 SV=2	174.0	[0..17]	[264..134]
gi\|89074722, gi\|... - gi\|89074722\|ref\|ZP_01161180.1\| ATP synthase subunit A [Photobacterium sp. SKA34], gi\|89049486\|gb\|EAR...	172.0	[0..4]	[263..5]
gi\|148143 - gi\|148143\|gb\|AAA24740.1\| ATPase, a subunit (EC 3.6.1.3)	172.0	[0..2]	[264..1]

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Predicted Domain #1

Region A:
Residues: [1-65]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYAQPKLTSA EYVQHHMSHW KLNLHNFTFT DGGFWTLNLD TLIISVVLGA LFILIFYIVA  60
   61 RRATA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.494	g.3.7	Scorpion toxin-like
View	Download	0.494	g.3.7	Scorpion toxin-like
View	Download	0.407	g.3.7	Scorpion toxin-like
View	Download	0.363	g.3.7	Scorpion toxin-like
View	Download	0.338	g.3.7	Scorpion toxin-like

Predicted Domain #2

Region A:
Residues: [66-264]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVPGKWQNAI EMAVEAVDGT VKDSFHGDRS LVAPLALTIF IWVFLMNFMD LVPVDLIPRL  60
   61 FQMGGVEHFK AVPTADPTLT FAMSITVFVL VIFYNFKMKG AIGLGKEVLS RPFGWYLMPI 120
  121 NVIFRLIDEG VKPISLALRL FGNLFAGELI FILIALLPWW SQFTLGMVWT LFHLLVITVQ 180
  181 AFIFMMLTVV YISLAAESH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.0
Match:	1c17M
Description:	F1F0 ATP synthase subunit A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrogen ion transporting ATP synthase activity, rotational mechanism	14.916062574431	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	13.3765277511271	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	11.6266555949852	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	10.5141571800158	bayes_pls_golite062009
cation transmembrane transporter activity	6.7755175807552	bayes_pls_golite062009
ion transmembrane transporter activity	6.66886754588748	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	6.24164033661356	bayes_pls_golite062009
proton-transporting ATPase activity, rotational mechanism	5.34968915140418	bayes_pls_golite062009
transporter activity	4.44683838532142	bayes_pls_golite062009
substrate-specific transporter activity	4.37473908570954	bayes_pls_golite062009
transmembrane transporter activity	4.36056336888635	bayes_pls_golite062009
cation-transporting ATPase activity	3.33662712450334	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	1.11865103919948	bayes_pls_golite062009
primary active transmembrane transporter activity	0.517601509369888	bayes_pls_golite062009
active transmembrane transporter activity	0.511311810386796	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	0.510137962484563	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	0.476924701765357	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	0.473395661531507	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	0.473285892250811	bayes_pls_golite062009
catalytic activity	0.276917867171685	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.242742762516199	bayes_pls_golite062009
pyrophosphatase activity	0.201337507209354	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.191294406773539	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.188721983770471	bayes_pls_golite062009
ATPase activity, coupled	0.110491424400621	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: