YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|29541539, gi\|...
Organism:	Coxiella burnetii RSA 493
Length:	217 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|29541539, gi|....

Description	E-value	Query Range	Subject Range
gi\|98660701 - gi\|98660701\|dbj\|GAA02123.1\| unnamed protein product [Pelotomaculum thermopropionicum SI]	203.0	[0..2]	[212..105]
gi\|82502198 - gi\|82502198\|gb\|ABB80126.1\| SubR [Bacillus subtilis]	198.0	[0..2]	[212..4]
gi\|10175779, gi\|... - gi\|15615719\|ref\|NP_244023.1\| two-component response regulator involved in phosphate regulation [Baci... gi\|25300880 - pir\|\|E84044 two-component response regulator involved in phosphate regulation phoP [imported] - Baci...	198.0	[0..3]	[212..4]
gi\|83588943, gi\|... - gi\|83588943\|ref\|YP_428952.1\| two component transcriptional regulator [Moorella thermoacetica ATCC 39...	198.0	[0..3]	[211..6]
gi\|51855517, gi\|... - gi\|51891828\|ref\|YP_074519.1\| two-component response regulator [Symbiobacterium thermophilum IAM 1486...	198.0	[0..3]	[209..5]
gi\|207090866 - gi\|207090866\|gb\|EDZ68137.1\| phosphate regulon transcriptional regulatory protein PhoB [Nitrosococcus... gi\|224411212, gi... - gi\|254434533\|ref\|ZP_05048041.1\| phosphate regulon transcriptional regulatory protein PhoB [Nitrosoco... gi\|76884178, gi\|... - gi\|77165864\|ref\|YP_344389.1\| phosphate regulon transcriptional regulatory protein phoB [Nitrosococcu...	198.0	[0..3]	[212..4]
gi\|28209958, gi\|... - gi\|28209958\|ref\|NP_780902.1\| transcriptional regulatory protein [Clostridium tetani E88], gi\|2820239...	197.0	[0..3]	[210..25]
gi\|7474358, gi\|4... - pir\|\|T31680 bacR protein - Bacillus licheniformis, gi\|4481749\|gb\|AAD21216.2\| BacR [Bacillus lichenif...	197.0	[0..2]	[212..4]
gi\|134051275, gi... - gi\|88945490\|ref\|ZP_01148660.1\| Response regulator receiver [Desulfotomaculum reducens MI-1], gi\|8892...	197.0	[0..1]	[211..1]

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Predicted Domain #1

Region A:
Residues: [1-217]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISVLLIEDH VLIRRGMRLM LEQIKGIRIV GEASTGEEGL ALRREKEPGV VILDFQLPDT  60
   61 NGLELARRLL RRDPEIKILV VTAMEGELLP MRLLEVGVRG FITKSSDSAE LERAIRAVHS 120
  121 GQRYIGSAIA SRLALSKTTA AKSPFDQLSN RQMEVLLLLA KGMNAESIAK QLHITAKTVN 180
  181 SHRYRMFEKL GVKNDVELIK LAVQYGLIDI DKTTSAV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	42.522879
Match:	1kgsA
Description:	PhoB; PhoB receiver domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
two-component response regulator activity	7.02872640261738	bayes_pls_golite062009
transcription regulator activity	5.23016166796951	bayes_pls_golite062009
signal transducer activity	4.51666042720644	bayes_pls_golite062009
molecular transducer activity	4.51666042720644	bayes_pls_golite062009
DNA binding	2.75354350283069	bayes_pls_golite062009
nucleic acid binding	2.67056525675208	bayes_pls_golite062009
protein histidine kinase activity	2.35011582062573	bayes_pls_golite062009
two-component sensor activity	2.32303301074957	bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor	2.28838869071567	bayes_pls_golite062009
transcription factor activity	2.12579037300919	bayes_pls_golite062009
binding	1.22427537074115	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: