YRC Public Data Repository - Protein Structure Prediction

Protein:	CLPP_COXBU
Organism:	Coxiella burnetii RSA 493
Length:	195 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CLPP_COXBU.

Description	E-value	Query Range	Subject Range
CLPP_VIBTL - ATP-dependent Clp protease proteolytic subunit OS=Vibrio tasmaniensis (strain LGP32) GN=clpP PE=3 SV... gi\|84387735, gi\|... - gi\|84387735\|ref\|ZP_00990751.1\| ATP-dependent Clp protease proteolytic subunit [Vibrio splendidus 12B...	275.0	[0..1]	[194..13]
gi\|85833328, gi\|... - gi\|86148885\|ref\|ZP_01067136.1\| ATP-dependent Clp protease proteolytic subunit [Vibrio sp. MED222], g...	275.0	[0..1]	[194..3]
gi\|90579278, gi\|... - gi\|90579278\|ref\|ZP_01235088.1\| ATP-dependent Clp protease proteolytic subunit [Vibrio angustum S14],... gi\|89073230, gi\|... - gi\|89073230\|ref\|ZP_01159760.1\| ATP-dependent Clp protease proteolytic subunit [Photobacterium sp. SK...	273.0	[0..4]	[194..16]
CLPP_THIDA - ATP-dependent Clp protease proteolytic subunit OS=Thiobacillus denitrificans (strain ATCC 25259) GN=...	271.0	[0..4]	[194..17]
CLPP_PHOPR - ATP-dependent Clp protease proteolytic subunit OS=Photobacterium profundum GN=clpP PE=3 SV=2 CLPP_PHOPR - ATP-dependent Clp protease proteolytic subunit OS=Photobacterium profundum (strain SS9) GN=clpP PE=3...	270.0	[0..4]	[194..8]
gi\|46914236, gi\|... - gi\|54309798\|ref\|YP_130818.1\| ATP-dependent Clp protease proteolytic subunit [Photobacterium profundu... gi\|27363512 - ref\|NP_759040.1\| ATP-dependent Clp protease, proteolytic subunit [Photobacterium profundum SS9]	270.0	[0..4]	[194..16]
gi\|90410782, gi\|... - gi\|90410782\|ref\|ZP_01218797.1\| ATP-dependent Clp protease proteolytic subunit [Photobacterium profun...	270.0	[0..4]	[194..16]
CLPP_VIBPA - ATP-dependent Clp protease proteolytic subunit OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIM... CLPP_VIBPA - ATP-dependent Clp protease proteolytic subunit OS=Vibrio parahaemolyticus GN=clpP PE=3 SV=1	270.0	[0..1]	[194..5]
gi\|91187849, gi\|... - gi\|91228617\|ref\|ZP_01262535.1\| ATP-dependent Clp protease proteolytic subunit [Vibrio alginolyticus ... gi\|75853478, gi\|... - gi\|75853478\|ref\|ZP_00761324.1\| COG0740: Protease subunit of ATP-dependent Clp proteases [Vibrio sp. ...	270.0	[0..1]	[194..13]
CLPP_VIBFM - ATP-dependent Clp protease proteolytic subunit OS=Vibrio fischeri (strain MJ11) GN=clpP PE=3 SV=1 CLPP_VIBF1 - ATP-dependent Clp protease proteolytic subunit OS=Vibrio fischeri (strain ATCC 700601 / ES114) GN=cl...	269.0	[0..1]	[194..13]

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Predicted Domain #1

Region A:
Residues: [1-195]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVLVPMVVE QTSRGERAYD IYSRLLKDRV IFLVGQVEDH MANLAIAQML FLESENPNKD  60
   61 INLYINSPGG AVTSAMAIYD TMQFVKPDVR TLCIGQAASA GALLLAGGAK GKRHCLPHSS 120
  121 VMIHQVLGGY QGQGTDIQIH AKQTQRVSDQ LNQILAKHTG KDIERVEKDT NRDYFLTPEE 180
  181 AVEYGLIDSI FKERP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	71.154902
Match:	1tyfA
Description:	Clp protease, ClpP subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.46154163027498	bayes_pls_golite062009
CoA carboxylase activity	0.939626895227199	bayes_pls_golite062009
acetyl-CoA carboxylase activity	0.764444938444292	bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds	0.621229080200493	bayes_pls_golite062009
enoyl-CoA hydratase activity	0.620657548610719	bayes_pls_golite062009
hydrolase activity	0.534319520590169	bayes_pls_golite062009
binding	0.367666848528835	bayes_pls_golite062009
ligase activity	0.32092496884003	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: