YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|29541114, gi\|...
Organism:	Coxiella burnetii RSA 493
Length:	114 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|29541114, gi|....

Description	E-value	Query Range	Subject Range
TRPR_PHOLL - Trp operon repressor OS=Photorhabdus luminescens subsp. laumondii GN=trpR PE=3 SV=1 TRPR_PHOLL - Trp operon repressor OS=Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / T...	126.0	[0..19]	[113..10]
TRPR_PASMU - Trp operon repressor homolog OS=Pasteurella multocida GN=trpR PE=3 SV=1 TRPR_PASMU - Trp operon repressor homolog OS=Pasteurella multocida (strain Pm70) GN=trpR PE=3 SV=1	120.0	[0..20]	[113..2]
TRPR_HAEIN - Trp operon repressor homolog OS=Haemophilus influenzae GN=trpR PE=3 SV=1 gi\|144983969 - gi\|144983969\|gb\|EDJ91411.1\| Trp operon repressor [Haemophilus influenzae R3021] TRPR_HAEIG - Trp operon repressor homolog OS=Haemophilus influenzae (strain PittGG) GN=trpR PE=3 SV=1 gi\|229844698, gi... - gi\|229844698\|ref\|ZP_04464837.1\| Trp operon repressor [Haemophilus influenzae 6P18H1], gi\|229812412\|g... gi\|229810885, gi... - gi\|229845881\|ref\|ZP_04465993.1\| Trp operon repressor [Haemophilus influenzae 7P49H1], gi\|229810885\|g... gi\|42630342 - gi\|42630342\|ref\|ZP_00155886.1\| COG2973: Trp operon repressor [Haemophilus influenzae R2846] gi\|42631147 - gi\|42631147\|ref\|ZP_00156685.1\| COG2973: Trp operon repressor [Haemophilus influenzae R2866] TRPR_HAEI8 - Trp operon repressor homolog OS=Haemophilus influenzae (strain 86-028NP) GN=trpR PE=3 SV=1 TRPR_HAEIN - Trp operon repressor homolog OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) G... TRPR_HAEIE - Trp operon repressor homolog OS=Haemophilus influenzae (strain PittEE) GN=trpR PE=3 SV=1 gi\|145272697, gi... - gi\|145638368\|ref\|ZP_01793978.1\| Trp operon repressor [Haemophilus influenzae PittII], gi\|145272697\|g... gi\|145634758, gi... - gi\|145634758\|ref\|ZP_01790466.1\| Trp operon repressor [Haemophilus influenzae PittAA], gi\|145267924\|g... gi\|145630579 - gi\|145630579\|ref\|ZP_01786359.1\| Trp operon repressor [Haemophilus influenzae 22.4-21] gi\|145628272, gi... - gi\|145628272\|ref\|ZP_01784073.1\| Trp operon repressor [Haemophilus influenzae 22.1-21], gi\|144980047\|...	118.0	[0..20]	[113..2]
TRPR_VIBVU - Trp operon repressor homolog OS=Vibrio vulnificus GN=trpR PE=3 SV=1 TRPR_VIBVU - Trp operon repressor homolog OS=Vibrio vulnificus (strain CMCP6) GN=trpR PE=3 SV=1 TRPR_VIBVY - Trp operon repressor homolog OS=Vibrio vulnificus (strain YJ016) GN=trpR PE=3 SV=1	117.0	[0..22]	[113..4]
gi\|1633316, gi\|1... - gi\|1633354\|pdb\|1RCS\|B Chain B, Nmr Study Of Trp Repressor-Operator Dna Complex, gi\|1633353\|pdb\|1RCS\|...	117.0	[0..16]	[113..4]
EG11029 - transcriptional repressor, tryptophan-binding / Autogenously regulated tryptophan repressor protein;... gi\|15804964, gi\|... - gi\|15804964\|ref\|NP_291006.1\| Trp operon repressor [Escherichia coli O157:H7 EDL933], gi\|12519422\|gb\|... TRPR_ECOHS - Trp operon repressor OS=Escherichia coli O9:H4 (strain HS) GN=trpR PE=3 SV=1 TRPR_ECO24 - Trp operon repressor OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=trpR PE=3 SV=1 TRPR_ECOLC - Trp operon repressor OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=trpR PE=3 SV=1 TRPR_SHIB3 - Trp operon repressor OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=trpR PE=3 SV=1 gi\|188492277, gi... - gi\|188492277\|ref\|ZP_02999547.1\| trp operon repressor [Escherichia coli 53638], gi\|188487476\|gb\|EDU62... gi\|191167398, gi... - gi\|191167398\|ref\|ZP_03029213.1\| trp operon repressor [Escherichia coli B7A], gi\|190902538\|gb\|EDV6227... gi\|124530361, gi... - gi\|124530361\|ref\|ZP_01701047.1\| Trp operon repressor [Escherichia coli B], gi\|124499252\|gb\|EAY46744.... gi\|193065636, gi... - gi\|193065636\|ref\|ZP_03046702.1\| trp operon repressor [Escherichia coli E22], gi\|192926709\|gb\|EDV8133... gi\|189000763, gi... - gi\|189000763\|gb\|EDU69749.1\| trp operon repressor [Escherichia coli O157:H7 str. EC4076], gi\|16878168... gi\|189374929, gi... - gi\|189374929\|gb\|EDU93345.1\| trp operon repressor [Escherichia coli O157:H7 str. EC869], gi\|168785038... gi\|168797968, gi... - gi\|189379535\|gb\|EDU97951.1\| trp operon repressor [Escherichia coli O157:H7 str. EC508], gi\|168797968... TRPR_ECODH - Trp operon repressor OS=Escherichia coli (strain K12 / DH10B) GN=trpR PE=3 SV=1 gi\|189356098, gi... - gi\|189356098\|gb\|EDU74517.1\| trp operon repressor [Escherichia coli O157:H7 str. EC4401], gi\|16875681... gi\|168762747, gi... - gi\|189366999\|gb\|EDU85415.1\| trp operon repressor [Escherichia coli O157:H7 str. EC4501], gi\|16876274... gi\|168766677, gi... - gi\|189364098\|gb\|EDU82517.1\| trp operon repressor [Escherichia coli O157:H7 str. EC4486], gi\|16876667... gi\|187768011, gi... - gi\|187768011\|gb\|EDU31855.1\| trp operon repressor [Escherichia coli O157:H7 str. EC4196], gi\|16877662... TRPR_SHIFL - Trp operon repressor OS=Shigella flexneri GN=trpR PE=3 SV=2 TRPR_ECOLI - Trp operon repressor - Escherichia coli gi\|24054962, gi\|... - gi\|24115622\|ref\|NP_710132.1\| Trp operon repressor [Shigella flexneri 2a str. 301], gi\|24054962\|gb\|AA... TRPR_ECO57 - Trp operon repressor OS=Escherichia coli O157:H7 GN=trpR PE=1 SV=2 gi\|188014921, gi... - gi\|188014921\|gb\|EDU53043.1\| trp operon repressor [Escherichia coli O157:H7 str. EC4113], gi\|16875096... TRPR_ECOBW - Trp operon repressor OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=trpR PE=3 SV=1 gi\|251787641, gi... - gi\|251787641\|ref\|YP_003001945.1\| hypothetical protein B21_04234 [Escherichia coli BL21], gi\|24237991... gi\|15834605, gi\|... - gi\|15834605\|ref\|NP_313378.1\| Trp operon repressor [Escherichia coli O157:H7 str. Sakai], gi\|13364829... TRPR_SHIF8 - Trp operon repressor OS=Shigella flexneri serotype 5b (strain 8401) GN=trpR PE=3 SV=1 gi\|237704129, gi... - gi\|237704129\|ref\|ZP_04534610.1\| trp operon repressor [Escherichia sp. 3_2_53FAA], gi\|226902041\|gb\|EE... gi\|253976222, gi... - gi\|254164319\|ref\|YP_003047429.1\| Trp operon repressor [Escherichia coli B str. REL606], gi\|253976222... gi\|254796389, gi... - gi\|254796389\|ref\|YP_003081226.1\| DNA-binding transcriptional repressor, tryptophan-binding [Escheric... EG11029 - transcriptional repressor, tryptophan-binding / Autogenously regulated tryptophan repressor protein;... gi\|254291070, gi... - gi\|254291070\|ref\|YP_003056820.1\| Trp operon repressor [Escherichia coli BL21(DE3)], gi\|253980379\|gb\|... gi\|254037405, gi... - gi\|254037405\|ref\|ZP_04871482.1\| trp operon repressor [Escherichia sp. 1_1_43], gi\|226840511\|gb\|EEH72... TRPR_SHIBS - Trp operon repressor OS=Shigella boydii serotype 4 (strain Sb227) GN=trpR PE=3 SV=1 gi\|89111101, gi\|... - gi\|89111101\|ref\|AP_004881.1\| DNA-binding transcriptional repressor, tryptophan-binding [Escherichia ... TRPR_SHISS - Trp operon repressor OS=Shigella sonnei (strain Ss046) GN=trpR PE=3 SV=1 TRPR_SHIDS - Trp operon repressor OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=trpR PE=3 SV=1 TRPR_ECOSE - Trp operon repressor OS=Escherichia coli (strain SE11) GN=trpR PE=3 SV=1 gi\|217321732, gi... - gi\|217325511\|ref\|ZP_03441595.1\| trp operon repressor [Escherichia coli O157:H7 str. TW14588], gi\|217... TRPR_ECO8A - Trp operon repressor OS=Escherichia coli O8 (strain IAI1) GN=trpR PE=3 SV=1 TRPR_ECO55 - Trp operon repressor OS=Escherichia coli (strain 55989 / EAEC) GN=trpR PE=3 SV=1 gi\|208725591, gi... - gi\|208805790\|ref\|ZP_03248127.1\| trp operon repressor [Escherichia coli O157:H7 str. EC4206], gi\|2087... gi\|208734403, gi... - gi\|208813126\|ref\|ZP_03254455.1\| trp operon repressor [Escherichia coli O157:H7 str. EC4045], gi\|2087... gi\|208821105, gi... - gi\|208821105\|ref\|ZP_03261425.1\| trp operon repressor [Escherichia coli O157:H7 str. EC4042], gi\|2087... TRPR_ECO5E - Trp operon repressor OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=trpR PE=3 SV=1 gi\|193070618, gi... - gi\|193070618\|ref\|ZP_03051556.1\| trp operon repressor [Escherichia coli E110019], gi\|192956101\|gb\|EDV... gi\|194429195, gi... - gi\|194429195\|ref\|ZP_03061724.1\| trp operon repressor [Escherichia coli B171], gi\|194412810\|gb\|EDX291... gi\|194421800, gi... - gi\|194439318\|ref\|ZP_03071397.1\| trp operon repressor [Escherichia coli 101-1], gi\|194421800\|gb\|EDX37... gi\|195937664 - gi\|195937664\|ref\|ZP_03083046.1\| Trp operon repressor [Escherichia coli O157:H7 str. EC4024]	117.0	[0..16]	[113..7]
TRPR_ENTCL - Trp operon repressor OS=Enterobacter cloacae GN=trpR PE=3 SV=1	116.0	[0..16]	[113..7]
gi\|190906567, gi... - gi\|191173182\|ref\|ZP_03034714.1\| trp operon repressor [Escherichia coli F11], gi\|190906567\|gb\|EDV6617... TRPR_ECO27 - Trp operon repressor OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=trpR PE=3 SV=1 TRPR_ECOUT - Trp operon repressor OS=Escherichia coli (strain UTI89 / UPEC) GN=trpR PE=3 SV=1 gi\|170122609, gi... - gi\|170768505\|ref\|ZP_02902958.1\| trp operon repressor [Escherichia albertii TW07627], gi\|170122609\|gb... TRPR_ECOK1 - Trp operon repressor OS=Escherichia coli O1:K1 / APEC GN=trpR PE=3 SV=1 sp\|B7UR23\|TRPR_ECO27 - Trp operon repressor OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=trpR PE=3 SV=1 TRPR_ECOL6 - Trp operon repressor OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=trpR PE=3 SV=... TRPR_ECOL6 - Trp operon repressor OS=Escherichia coli O6 GN=trpR PE=3 SV=3 gi\|227837944, gi... - gi\|227885115\|ref\|ZP_04002920.1\| TrpR family transcriptional regulator [Escherichia coli 83972], gi\|2... TRPR_ECOL5 - Trp operon repressor OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=trpR PE=3 SV=1 TRPR_ECO45 - Trp operon repressor OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=trpR PE=3 SV=1 TRPR_ECO81 - Trp operon repressor OS=Escherichia coli O81 (strain ED1a) GN=trpR PE=3 SV=1	116.0	[0..16]	[113..7]

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Predicted Domain #1

Region A:
Residues: [1-114]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLFFSHCLI PKRLVYGECK VPLKSEGWRG FLTLCQKAET VDQLDELFGL LFTLEEKEQL  60
   61 ALRVELVRAL LRGEKPQREI AHDLNISIAK ITRGSNALKT TSDKIKSFIK KYLP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.221849
Match:	1rcsA
Description:	Trp repressor, TrpR
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleic acid binding	1.49137583648289	bayes_pls_golite062009
DNA binding	1.47393364683412	bayes_pls_golite062009
binding	0.833538516780913	bayes_pls_golite062009
sequence-specific DNA binding	0.47954468042493	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: