YRC Public Data Repository - Protein Structure Prediction

Protein:	DUS1_SYNY3
Organism:	Synechocystis sp. PCC 6803 substr. Kazusa
Length:	355 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DUS1_SYNY3.

Description	E-value	Query Range	Subject Range
gi\|67853187, gi\|... - gi\|67924974\|ref\|ZP_00518361.1\| Dihydrouridine synthase TIM-barrel protein nifR3 [Crocosphaera watson...	292.0	[0..22]	[352..5]
gi\|25332175 - pir\|\|AH1959 hypothetical protein all1227 [imported] - Nostoc sp. (strain PCC 7120) gi\|17130574, gi\|... - gi\|17228722\|ref\|NP_485270.1\| hypothetical protein all1227 [Nostoc sp. PCC 7120], gi\|17130574\|dbj\|BAB...	290.0	[0..19]	[351..1]
gi\|48892593, gi\|... - gi\|71677303\|ref\|ZP_00675041.1\| Dihydrouridine synthase TIM-barrel protein nifR3 [Trichodesmium eryth...	290.0	[0..28]	[349..11]
gi\|75906868, gi\|... - gi\|75906868\|ref\|YP_321164.1\| dihydrouridine synthase TIM-barrel protein nifR3 [Anabaena variabilis A...	287.0	[0..27]	[351..10]
gi\|186466566, gi... - gi\|23130352\|ref\|ZP_00112169.1\| COG0042: tRNA-dihydrouridine synthase [Nostoc punctiforme PCC 73102],...	285.0	[0..26]	[351..9]
gi\|22298534, gi\|... - gi\|22298534\|ref\|NP_681781.1\| nitrogen regulation protein NifR3-like protein [Thermosynechococcus elo...	283.0	[0..17]	[354..2]
gi\|56552023, gi\|... - gi\|56552023\|ref\|YP_162862.1\| tRNA-dihydrouridine synthase [Zymomonas mobilis subsp. mobilis ZM4], gi...	271.0	[0..25]	[349..8]
DUS1_BACSU - Probable tRNA-dihydrouridine synthase 1 OS=Bacillus subtilis GN=dus1 PE=3 SV=1 gi\|221321409 - gi\|221321409\|ref\|ZP_03602703.1\| hypothetical protein BsubsS_00410 [Bacillus subtilis subsp. subtilis... gi\|221317146 - gi\|221317146\|ref\|ZP_03598440.1\| hypothetical protein BsubsJ_00410 [Bacillus subtilis subsp. subtilis... DUS1_BACSU - Probable tRNA-dihydrouridine synthase 1 OS=Bacillus subtilis (strain 168) GN=dus1 PE=3 SV=1 gi\|221312213 - gi\|221312213\|ref\|ZP_03594018.1\| hypothetical protein BsubsN3_00410 [Bacillus subtilis subsp. subtili...	270.0	[0..33]	[353..2]
gi\|52424587, gi\|... - gi\|52424587\|ref\|YP_087724.1\| hypothetical protein MS0532 [Mannheimia succiniciproducens MBEL55E], gi...	270.0	[0..22]	[352..8]
gi\|67916662, gi\|... - gi\|67916662\|ref\|ZP_00510363.1\| Dihydrouridine synthase TIM-barrel protein nifR3 [Clostridium thermoc... gi\|196253182, gi... - gi\|196253182\|ref\|ZP_03151820.1\| TIM-barrel protein, nifR3 family [Clostridium thermocellum DSM 4150]...	268.0	[0..33]	[350..1]

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Predicted Domain #1

Region A:
Residues: [1-355]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKCSYRFIS LQTLTPNSLL DHSPNPTIWA KPLQIGSLTL HSRVLQSPLS GVTDLVFRRL  60
   61 VRRYAPQAML YTEMVSATEI HHLRTLPQVM EIDPRENPIS IQLFDCRPDF MAEAAQKAVA 120
  121 QGAQSVDINM GCPVNKITKK GGGSSLLRQP AVAEAIVKTV VAAVDVPVTV KTRLGWDDGE 180
  181 INIVEFAQRL QDAGAQMLTL HGRTRAQGYN GRARWQWIAK VKQALTIPVI ANGDIFSVEA 240
  241 AIACLEETGA DGVMCSRGSL GYPFLVGEIE HFFKTGEKRK APTVAEKLTC AQEHLQMLWE 300
  301 YKGQRGLFQA RKHLAWYCKD FPGAAALREQ LFQINSVQEG KDLLDQAIST AKLCL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.69897
Match:	1vhnA
Description:	Crystal structure of a putative flavin oxidoreductase with flavin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.94749091175302	bayes_pls_golite062009
tRNA dihydrouridine synthase activity	1.94490879164338	bayes_pls_golite062009
nucleic acid binding	1.03692680161964	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	0.876786102965635	bayes_pls_golite062009
oxidoreductase activity	0.80115790656025	bayes_pls_golite062009
binding	0.68572942532795	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: