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View Structure Prediction Details

Protein: gi|24375491, gi|...
Organism: Shewanella oneidensis MR-1
Length: 408 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24375491, gi|....

Description E-value Query
Range
Subject
Range
gi|114637062 - gi|114637062|ref|XP_508369.2| PREDICTED: solute carrier family 1, member 2 [Pan troglodytes]
388.0 [0..4] [406..173]
gi|68364150 - gi|68364150|ref|XP_689294.1| PREDICTED: similar to solute carrier family 1 (glial high affinity glut...
381.0 [0..18] [406..127]
gi|76636256 - gi|76636256|ref|XP_614642.2| PREDICTED: similar to Excitatory amino acid transporter 2 (Sodium-depen...
370.0 [0..4] [406..57]
gi|74146199 - gi|74146199|dbj|BAE24235.1| unnamed protein product [Mus musculus]
365.0 [0..1] [406..37]
EAA2_RAT - Excitatory amino acid transporter 2 OS=Rattus norvegicus GN=Slc1a2 PE=1 SV=2
gi|386355 - gi|386355|gb|AAB27233.1| L-glutamate transporter, GLT-1 [rats, brain, Peptide, 573 aa]
365.0 [0..1] [406..37]
gi|57163875, gi|... - gi|57163875|ref|NP_001009334.1| glutamate transporter GLT1 [Felis catus], gi|13569725|gb|AAK31212.1|...
364.0 [0..4] [406..40]

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Predicted Domain #1
Region A:
Residues: [1-408]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMKSLSTRIF IGLFTGLILG TLVQYFLNDI GFFSGNLVEL ASGVGTMFVN MIMMLVVPLV  60
   61 FVSIVCGVCE LQDLKSFGRL GGKTFGFYIV NTVVAISTAL LVVLLLDPGK GVDMSSADGV 120
  121 AITATELPSL IALLIDIVPR NPVAAFMSGN MLQVIFMALM LGGVMKSLGE HVAGAVQGFQ 180
  181 TANKIMMKLI SVVMSLAPFG VFALMFKLGA TLDAAVFMSV LEYLVIILAL LLLWIFVVYP 240
  241 LSVGMFTPIS AKTFRAKTQE QVLFSLSTAS SNATIPVTMR TLTEKLGVNR AVAGFGVPLG 300
  301 ATMNMGGVAI YITIAIFFVA NAFGMPITSE QLPSLLFSIF LLSVGAGGVP GGGMVMIGVL 360
  361 IHQMGLPIEA FAIVAALDRI IDMVLTSCNV VGDTAVLTIV DQTEKAVK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 82.154902
Match: 1xfhA
Description: Structure of glutamate transporter homolog from Pyrococcus horikoshii
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
dicarboxylic acid transmembrane transporter activity 5.4077039375589 bayes_pls_golite062009
carboxylic acid transmembrane transporter activity 5.35323738672724 bayes_pls_golite062009
organic acid transmembrane transporter activity 5.3122318185646 bayes_pls_golite062009
sodium:dicarboxylate symporter activity 4.40071591934747 bayes_pls_golite062009
anion:cation symporter activity 4.38991307992111 bayes_pls_golite062009
amino acid transmembrane transporter activity 3.64519243918556 bayes_pls_golite062009
transporter activity 3.59726235774831 bayes_pls_golite062009
transmembrane transporter activity 3.48998062737764 bayes_pls_golite062009
substrate-specific transporter activity 3.25811511579861 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.16015523656183 bayes_pls_golite062009
active transmembrane transporter activity 3.11723298209538 bayes_pls_golite062009
amine transmembrane transporter activity 2.90153102682056 bayes_pls_golite062009
organic acid:sodium symporter activity 2.72996970117754 bayes_pls_golite062009
ion transmembrane transporter activity 2.5316793478278 bayes_pls_golite062009
L-aspartate transmembrane transporter activity 2.53126289198474 bayes_pls_golite062009
symporter activity 2.37209552756137 bayes_pls_golite062009
solute:cation symporter activity 2.37209552756137 bayes_pls_golite062009
secondary active transmembrane transporter activity 2.36442337809135 bayes_pls_golite062009
cation transmembrane transporter activity 2.31510944441012 bayes_pls_golite062009
L-amino acid transmembrane transporter activity 2.2399865852858 bayes_pls_golite062009
C4-dicarboxylate transmembrane transporter activity 2.22681603191212 bayes_pls_golite062009
acidic amino acid transmembrane transporter activity 1.63992398037381 bayes_pls_golite062009
L-glutamate transmembrane transporter activity 1.63992398037381 bayes_pls_golite062009
anion transmembrane transporter activity 0.727865493684019 bayes_pls_golite062009
solute:sodium symporter activity 0.63565466616857 bayes_pls_golite062009
solute:hydrogen symporter activity 0.54912532283943 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle