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View Structure Prediction Details

Protein: GLYA_SHEON
Organism: Shewanella oneidensis MR-1
Length: 417 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLYA_SHEON.

Description E-value Query
Range
Subject
Range
GLYA_HALHL - Serine hydroxymethyltransferase OS=Halorhodospira halophila (strain DSM 244 / SL1) GN=glyA PE=3 SV=1
368.0 [0..1] [417..1]
GLYA_SHELP - Serine hydroxymethyltransferase OS=Shewanella loihica (strain ATCC BAA-1088 / PV-4) GN=glyA PE=3 SV=...
366.0 [0..1] [417..1]
GLYA_SHEB9 - Serine hydroxymethyltransferase OS=Shewanella baltica (strain OS195) GN=glyA PE=3 SV=1
363.0 [0..1] [417..1]
GLYA_AZOVD - Serine hydroxymethyltransferase OS=Azotobacter vinelandii (strain DJ / ATCC BAA-1303) GN=glyA PE=3 S...
gi|53612840, gi|... - gi|67154318|ref|ZP_00416063.1| Glycine hydroxymethyltransferase [Azotobacter vinelandii AvOP], ref|Z...
363.0 [0..1] [417..1]
GLYA_SHEB5 - Serine hydroxymethyltransferase OS=Shewanella baltica (strain OS155 / ATCC BAA-1091) GN=glyA PE=3 SV...
363.0 [0..1] [417..1]
gi|77958563, gi|... - gi|77958563|ref|ZP_00822594.1| COG0112: Glycine/serine hydroxymethyltransferase [Yersinia bercovieri...
362.0 [0..1] [416..1]
gi|238796764, gi... - gi|77963401|ref|ZP_00827211.1| COG0112: Glycine/serine hydroxymethyltransferase [Yersinia mollaretii...
361.0 [0..1] [416..1]
GLYA_SHESM - Serine hydroxymethyltransferase OS=Shewanella sp. (strain MR-4) GN=glyA PE=3 SV=1
361.0 [0..1] [417..1]
GLYA_SHEAM - Serine hydroxymethyltransferase OS=Shewanella amazonensis (strain ATCC BAA-1098 / SB2B) GN=glyA PE=3...
361.0 [0..1] [417..1]
GLYA_SHESA - Serine hydroxymethyltransferase OS=Shewanella sp. (strain ANA-3) GN=glyA PE=3 SV=1
GLYA_SHESR - Serine hydroxymethyltransferase OS=Shewanella sp. (strain MR-7) GN=glyA PE=3 SV=1
361.0 [0..1] [417..1]

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Predicted Domain #1
Region A:
Residues: [1-417]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKKDMNIAD YDPELFNAIQ NETLRQEEHI ELIASENYTS PRVMQAQGSQ LTNKYAEGYP  60
   61 GKRYYGGCEY VDVVETLAIE RAKQLFGATY ANVQPHSGSQ ANSAVYMALL KPGDTVLGMN 120
  121 LAHGGHLTHG SPVNFSGRLY NIIPYGIDES GKIDYDEMER LAVEHKPKMM IGGFSAYSGI 180
  181 VDWARMREIA DKIGAYLFVD MAHVAGLIAA GVYPNPVPHA HVVTSTTHKT LAGPRGGIIL 240
  241 SAADDEELYK KLNSAVFPGG QGGPLMHVIA GKAVAFKEAL EPEFKTYQQQ VVNNAKAMVE 300
  301 VFLERGYKIV SGGTSNHLML VDLIGRDLTG KEADAALGSA NITVNKNSVP NDPRSPFVTS 360
  361 GVRIGTPAIT RRGFKEAEAK QLTGWICDIL DDAHNPAVIE RVKGQVLALC ARFPVYG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 94.0
Match: 1dfoA
Description: Serine hydroxymethyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
L-aspartate:2-oxoglutarate aminotransferase activity 3.359406422625 bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity 3.2128372762799 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 3.2128372762799 bayes_pls_golite062009
transferase activity 2.59075614411581 bayes_pls_golite062009
catalytic activity 2.29878871754893 bayes_pls_golite062009
transferase activity, transferring nitrogenous groups 1.28316822767388 bayes_pls_golite062009
transaminase activity 1.24990480711889 bayes_pls_golite062009
transferase activity, transferring acyl groups 1.19150094103499 bayes_pls_golite062009
transcription regulator activity 1.07873942461292 bayes_pls_golite062009
O-phospho-L-serine:2-oxoglutarate aminotransferase activity 0.994935084630764 bayes_pls_golite062009
DNA binding 0.886628214497634 bayes_pls_golite062009
nucleic acid binding 0.814403324199462 bayes_pls_golite062009
structural molecule activity 0.754675308623467 bayes_pls_golite062009
methyltransferase activity 0.681623261233707 bayes_pls_golite062009
vitamin binding 0.66463470119531 bayes_pls_golite062009
binding 0.661198018681765 bayes_pls_golite062009
transcription factor activity 0.615294010373048 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 0.60304280865376 bayes_pls_golite062009
5-aminolevulinate synthase activity 0.54326874956263 bayes_pls_golite062009
L-allo-threonine aldolase activity 0.500744432308415 bayes_pls_golite062009
glycine hydroxymethyltransferase activity 0.271623203801431 bayes_pls_golite062009
pyridoxal phosphate binding 0.16957228630576 bayes_pls_golite062009
vitamin B6 binding 0.16957228630576 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle