YRC Public Data Repository - Protein Structure Prediction

Protein:	TRPA_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	278 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TRPA_SHEON.

Description	E-value	Query Range	Subject Range
TRPA_PHOLL - Tryptophan synthase alpha chain OS=Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP... TRPA_PHOLL - Tryptophan synthase alpha chain OS=Photorhabdus luminescens subsp. laumondii GN=trpA PE=3 SV=1	259.0	[0..13]	[278..1]
gi\|186464184, gi... - gi\|23128273\|ref\|ZP_00110124.1\| COG0159: Tryptophan synthase alpha chain [Nostoc punctiforme PCC 7310...	258.0	[0..13]	[277..1]
gi\|67925738, gi\|... - gi\|67925738\|ref\|ZP_00519045.1\| Tryptophan synthase, alpha chain [Crocosphaera watsonii WH 8501], gi\|...	257.0	[0..13]	[277..1]
gi\|17133948, gi\|... - gi\|17232303\|ref\|NP_488851.1\| tryptophan synthase subunit alpha [Nostoc sp. PCC 7120], gi\|17133948\|db... gi\|25291896 - pir\|\|AC2407 tryptophan synthase alpha chain [imported] - Nostoc sp. (strain PCC 7120)	257.0	[0..13]	[277..1]
TRPA1_ARATH - Tryptophan synthase alpha chain OS=Arabidopsis thaliana GN=TRPA1 PE=1 SV=2	257.0	[0..8]	[277..5]
gi\|86605970, gi\|... - gi\|86605970\|ref\|YP_474733.1\| tryptophan synthase subunit alpha [Synechococcus sp. JA-3-3Ab], gi\|8655... gi\|86605970 - gi\|86605970\|ref\|YP_474733.1\| tryptophan synthase, alpha subunit [Cyanobacteria bacterium Yellowstone...	256.0	[0..14]	[277..3]
TRPA_SYNP2 - Tryptophan synthase alpha chain OS=Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) GN=trpA P...	256.0	[0..13]	[277..1]
gi\|84489869, gi\|... - gi\|84489869\|ref\|YP_448101.1\| tryptophan synthase subunit alpha [Methanosphaera stadtmanae DSM 3091],...	254.0	[0..12]	[278..2]

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Predicted Domain #1

Region A:
Residues: [1-278]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSISNQTIP HQASRYQAAF SRLKAEGRGA FVPFVTLGDP SPELSLKIID TLVQNGADAL  60
   61 ELGFPFSDPL ADGPVIQGAN LRALAAGTTP TACFELLAKI RAKYPELPIG LLLYANLVFA 120
  121 NGIDAFYAKA QQAGVDSVLI ADVPVEEAAP FIQAAKAHGI APIFIAPPNA DSDTLAKVSQ 180
  181 SGEGYTYLLS RAGVTGADTK AGTPVEEILA KLQEFNAPPP LLGFGIAEPA QVSAAIKAGA 240
  241 AGAISGSAVV KIIETHQQDE VKLLAALGEF TRTMKAAT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	64.69897
Match:	1a50A
Description:	Trp synthase alpha-subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
tryptophan synthase activity	3.15663465352598	bayes_pls_golite062009
indole-3-glycerol-phosphate synthase activity	3.12120866545322	bayes_pls_golite062009
catalytic activity	2.81275055404078	bayes_pls_golite062009
phosphoribosylanthranilate isomerase activity	2.655130814615	bayes_pls_golite062009
carbon-carbon lyase activity	2.44001937916931	bayes_pls_golite062009
carboxy-lyase activity	1.80978905789979	bayes_pls_golite062009
lyase activity	0.9228652996943	bayes_pls_golite062009
imidazoleglycerol-phosphate synthase activity	0.82314869965119	bayes_pls_golite062009
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity	0.302746738903759	bayes_pls_golite062009
isomerase activity	0.14149405165663	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: