YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24374432, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	322 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24374432, gi|....

Description	E-value	Query Range	Subject Range
gi\|70728897, gi\|... - gi\|70728897\|ref\|YP_258646.1\| cysteine synthase A [Pseudomonas fluorescens Pf-5], gi\|68343196\|gb\|AAY9...	346.0	[0..1]	[322..46]
gi\|87121648, gi\|... - gi\|87121648\|ref\|ZP_01077536.1\| cysteine synthase A [Marinomonas sp. MED121], gi\|86163180\|gb\|EAQ64457...	338.0	[0..3]	[322..4]
gi\|77360850, gi\|... - gi\|77360850\|ref\|YP_340425.1\| O-acetylserine sulfhydrylase, PLP-dependent enzyme [Pseudoalteromonas h...	332.0	[0..1]	[322..1]
gi\|67850867, gi\|... - gi\|67874931\|ref\|ZP_00504482.1\| Cysteine synthase K/M:Cysteine synthase K [Clostridium thermocellum A... gi\|196252125, gi... - gi\|196252125\|ref\|ZP_03150787.1\| cysteine synthase A [Clostridium thermocellum DSM 4150], gi\|19619839...	327.0	[0..1]	[313..1]
gi\|145589657, gi... - gi\|145589657\|ref\|YP_001156254.1\| cysteine synthase A [Polynucleobacter necessarius subsp. asymbiotic...	326.0	[0..5]	[320..4]
gi\|157155432, gi... - gi\|75187168\|ref\|ZP_00700435.1\| COG0031: Cysteine synthase [Escherichia coli E24377A], gi\|157155432\|r...	326.0	[0..1]	[322..1]
gi\|84780198, gi\|... - gi\|85059678\|ref\|YP_455380.1\| cysteine synthase A [Sodalis glossinidius str. 'morsitans'], gi\|8478019...	325.0	[0..1]	[315..1]
gi\|226901304, gi... - gi\|237704938\|ref\|ZP_04535419.1\| cysteine synthase A [Escherichia sp. 3_2_53FAA], gi\|226901304\|gb\|EEH... gi\|227887460, gi... - gi\|227887460\|ref\|ZP_04005265.1\| cysteine synthase A [Escherichia coli 83972], gi\|227835810\|gb\|EEJ462... EG10192 - cysteine synthase A, O-acetylserine sulfhydrolase A subunit / Cysteine synthase A, O-acetylserine su... gi\|215265741, gi... - gi\|215487669\|ref\|YP_002330100.1\| cysteine synthase A [Escherichia coli O127:H6 str. E2348/69], gi\|21... gi\|217327815, gi... - gi\|217327815\|ref\|ZP_03443898.1\| cysteine synthase A [Escherichia coli O157:H7 str. TW14588], gi\|2173... gi\|218554947, gi... - gi\|218554947\|ref\|YP_002387860.1\| cysteine synthase A [Escherichia coli IAI1], gi\|218361715\|emb\|CAQ99... gi\|218559362, gi... - gi\|218559362\|ref\|YP_002392275.1\| cysteine synthase A [Escherichia coli S88], gi\|218366131\|emb\|CAR038... gi\|218690552, gi... - gi\|218690552\|ref\|YP_002398764.1\| cysteine synthase A [Escherichia coli ED1a], gi\|218428116\|emb\|CAR08... gi\|218696050, gi... - gi\|218696050\|ref\|YP_002403717.1\| cysteine synthase A [Escherichia coli 55989], gi\|218352782\|emb\|CAU9... gi\|218433019, gi... - gi\|218705922\|ref\|YP_002413441.1\| cysteine synthase A [Escherichia coli UMN026], gi\|218433019\|emb\|CAR... gi\|15832540, gi\|... - gi\|15832540\|ref\|NP_311313.1\| cysteine synthase A [Escherichia coli O157:H7 str. Sakai], gi\|13362756\|... gi\|110642598, gi... - gi\|110642598\|ref\|YP_670328.1\| cysteine synthase A [Escherichia coli 536], gi\|110344190\|gb\|ABG70427.1... gi\|91073326, gi\|... - gi\|91211752\|ref\|YP_541738.1\| cysteine synthase A [Escherichia coli UTI89], gi\|91073326\|gb\|ABE08207.1... gi\|74312950, gi\|... - gi\|74312950\|ref\|YP_311369.1\| cysteine synthase A [Shigella sonnei Ss046], gi\|73856427\|gb\|AAZ89134.1\|... gi\|89109228, gi\|... - gi\|89109228\|ref\|AP_003008.1\| cysteine synthase A, O-acetylserine sulfhydrolase A subunit [Escherichi... gi\|192955482, gi... - gi\|75233889\|ref\|ZP_00718352.1\| COG0031: Cysteine synthase [Escherichia coli E110019], gi\|193071211\|r... gi\|75515757, gi\|... - gi\|75515757\|ref\|ZP_00737892.1\| COG0031: Cysteine synthase [Escherichia coli 53638], gi\|188494912\|ref... gi\|117624622, gi... - gi\|117624622\|ref\|YP_853535.1\| cysteine synthase A [Escherichia coli APEC O1], gi\|115513746\|gb\|ABJ018... gi\|124498312, gi... - gi\|124531829\|ref\|ZP_01701936.1\| cysteine synthase A [Escherichia coli B], gi\|124498312\|gb\|EAY45829.1... gi\|194437698, gi... - gi\|83586928\|ref\|ZP_00925559.1\| COG0031: Cysteine synthase [Escherichia coli 101-1], gi\|194437698\|ref... gi\|75207919, gi\|... - gi\|75207919\|ref\|ZP_00708367.1\| COG0031: Cysteine synthase [Escherichia coli B171], gi\|194430695\|ref\|... gi\|191168979, gi... - gi\|75227746\|ref\|ZP_00714475.1\| COG0031: Cysteine synthase [Escherichia coli B7A], gi\|191168979\|ref\|Z... gi\|75177826, gi\|... - gi\|75177826\|ref\|ZP_00697888.1\| COG0031: Cysteine synthase [Shigella boydii BS512], gi\|187732652\|ref\|... gi\|157161879, gi... - gi\|75196427\|ref\|ZP_00706497.1\| COG0031: Cysteine synthase [Escherichia coli HS], gi\|157161879\|ref\|YP... gi\|170082023, gi... - gi\|170082023\|ref\|YP_001731343.1\| cysteine synthase A, O-acetylserine sulfhydrolase A subunit [Escher... gi\|170683441, gi... - gi\|170683441\|ref\|YP_001744605.1\| cysteine synthase A [Escherichia coli SMS-3-5], gi\|170521159\|gb\|ACB... gi\|195940540 - gi\|195940540\|ref\|ZP_03085922.1\| cysteine synthase A [Escherichia coli O157:H7 str. EC4024] gi\|208807417, gi... - gi\|208807417\|ref\|ZP_03249754.1\| cysteine synthase A [Escherichia coli O157:H7 str. EC4206], gi\|20872... gi\|208812017, gi... - gi\|208812017\|ref\|ZP_03253346.1\| cysteine synthase A [Escherichia coli O157:H7 str. EC4045], gi\|20873... gi\|208740609, gi... - gi\|208820486\|ref\|ZP_03260806.1\| cysteine synthase A [Escherichia coli O157:H7 str. EC4042], gi\|20874... gi\|209160827, gi... - gi\|209399427\|ref\|YP_002271893.1\| cysteine synthase A [Escherichia coli O157:H7 str. EC4115], gi\|2091... CYSK_ECOLI - Cysteine synthase A (EC 2.5.1.47) (O-acetylserine sulfhydrylase A) (O-acetylserine (Thiol)-lyase A) ... gi\|209919896, gi... - gi\|209919896\|ref\|YP_002293980.1\| cysteine synthase A [Escherichia coli SE11], gi\|209913155\|dbj\|BAG78... CYSK_ECO57 - Cysteine synthase A OS=Escherichia coli O157:H7 GN=cysK PE=3 SV=2 EG10192 - cysteine synthase A, O-acetylserine sulfhydrolase A subunit / Cysteine synthase A, O-acetylserine su... gi\|12516787, gi\|... - gi\|15802947\|ref\|NP_288976.1\| cysteine synthase A [Escherichia coli O157:H7 EDL933], gi\|12516787\|gb\|A... gi\|254593768, gi... - gi\|254794368\|ref\|YP_003079205.1\| cysteine synthase A, O-acetylserine sulfhydrolase A subunit [Escher... gi\|168759063, gi... - gi\|189354278\|gb\|EDU72697.1\| cysteine synthase A [Escherichia coli O157:H7 str. EC4401], gi\|168759063... gi\|253974298, gi... - gi\|254162397\|ref\|YP_003045505.1\| cysteine synthase A, O-acetylserine sulfhydrolase A subunit [Escher... gi\|168768503, gi... - gi\|189362241\|gb\|EDU80660.1\| cysteine synthase A [Escherichia coli O157:H7 str. EC4486], gi\|168768503... gi\|254289158, gi... - gi\|254289158\|ref\|YP_003054906.1\| cysteine synthase A, O-acetylserine sulfhydrolase A subunit [Escher... gi\|189003244, gi... - gi\|189003244\|gb\|EDU72230.1\| cysteine synthase A [Escherichia coli O157:H7 str. EC4076], gi\|168778377... gi\|251785748, gi... - gi\|251785748\|ref\|YP_003000052.1\| hypothetical protein B21_02275 [Escherichia coli BL21], gi\|24237802... gi\|169754231, gi... - gi\|170019303\|ref\|YP_001724257.1\| cysteine synthase A [Escherichia coli ATCC 8739], gi\|169754231\|gb\|A... gi\|238860695, gi... - gi\|238901577\|ref\|YP_002927373.1\| cysteine synthase A, O-acetylserine sulfhydrolase A subunit [Escher...	324.0	[0..1]	[322..1]
gi\|24052837, gi\|... - gi\|24113759\|ref\|NP_708269.1\| cysteine synthase A [Shigella flexneri 2a str. 301], gi\|24052837\|gb\|AAN... gi\|110615903, gi... - gi\|110806355\|ref\|YP_689875.1\| cysteine synthase A [Shigella flexneri 5 str. 8401], gi\|110615903\|gb\|A...	324.0	[0..1]	[322..1]
gi\|90328195, gi\|... - gi\|90410982\|ref\|ZP_01218996.1\| putative cysteine synthase A [Photobacterium profundum 3TCK], gi\|9032...	324.0	[0..1]	[322..1]

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Predicted Domain #1

Region A:
Residues: [1-322]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKIFEDNSY TIGNTPLVRL NRVSQGKVLA KVESRNPSFS VKCRIGANMI WDAEKKGLLT  60
   61 KDHELIEPTS GNTGIALAYV AAARGYKLTL TMPNTMSLER RKLLKALGAN LVLTEGAKGM 120
  121 KGAIDKAEEI RQSAPEKYIL LQQFNNPANP EIHEKTTGPE IWNDTDGAVD VFVAGVGTGG 180
  181 TITGVSRYLK KVAGKAITSV AVEPADSPVI TQTLAGLPVQ PGPHKIQGIG AGFIPGNLDI 240
  241 ELIDRVETVT NDEAIEMARR LMQEEGILVG ISSGAAVVAA NRIAALPEFA DKTIVVVLPS 300
  301 AAERYLSSVL FQGQFGDEEN IQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	86.522879
Match:	1fcjA
Description:	O-acetylserine sulfhydrylase (Cysteine synthase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
cysteine synthase activity	5.18562032111987	bayes_pls_golite062009
catalytic activity	2.38994231321972	bayes_pls_golite062009
lyase activity	1.87743897464083	bayes_pls_golite062009
cystathionine beta-synthase activity	1.4517088142802	bayes_pls_golite062009
tryptophan synthase activity	1.04832999357666	bayes_pls_golite062009
carbon-oxygen lyase activity	0.923824749425553	bayes_pls_golite062009
threonine synthase activity	0.727838845253199	bayes_pls_golite062009
ammonia-lyase activity	0.476674617721478	bayes_pls_golite062009
L-threonine ammonia-lyase activity	0.37325071016009	bayes_pls_golite062009
carbon-nitrogen lyase activity	0.249761226675912	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: