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View Structure Prediction Details

Protein: URK_SHEON
Organism: Shewanella oneidensis MR-1
Length: 212 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for URK_SHEON.

Description E-value Query
Range
Subject
Range
gi|76611769 - gi|76611769|ref|XP_614178.2| PREDICTED: similar to uridine-cytidine kinase 2 [Bos taurus]
215.0 [0..2] [210..233]
UCK1_DANRE - Uridine-cytidine kinase 1 OS=Danio rerio GN=uck1 PE=2 SV=1
214.0 [0..3] [210..14]
gi|144982771 - gi|144982771|gb|EDJ90300.1| uridine kinase [Haemophilus influenzae R3021]
URK_HAEIG - Uridine kinase OS=Haemophilus influenzae (strain PittGG) GN=udk PE=3 SV=1
gi|145631637 - gi|145631637|ref|ZP_01787402.1| uridine kinase [Haemophilus influenzae 22.4-21]
URK_HAEI8 - Uridine kinase OS=Haemophilus influenzae (strain 86-028NP) GN=udk PE=3 SV=1
URK_HAEIN - Uridine kinase OS=Haemophilus influenzae GN=udk PE=3 SV=1
gi|46128859 - gi|46128859|ref|ZP_00154371.2| COG0572: Uridine kinase [Haemophilus influenzae R2846]
gi|46132963 - gi|46132963|ref|ZP_00155965.2| COG0572: Uridine kinase [Haemophilus influenzae R2866]
URK_HAEIN - Uridine kinase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) GN=udk PE=3 SV=...
213.0 [0..1] [212..1]
gi|48425793, gi|... - gi|48425800|pdb|1UJ2|B Chain B, Crystal Structure Of Human Uridine-Cytidine Kinase 2 Complexed With ...
211.0 [0..2] [210..18]
gi|26350013 - gi|26350013|dbj|BAC38646.1| unnamed protein product [Mus musculus]
209.0 [0..2] [210..16]
URK_SHEAM - Uridine kinase OS=Shewanella amazonensis (strain ATCC BAA-1098 / SB2B) GN=udk PE=3 SV=1
208.0 [0..1] [212..1]
gi|46912791, gi|... - gi|54308363|ref|YP_129383.1| uridine kinase [Photobacterium profundum SS9], gi|46912791|emb|CAG19581...
207.0 [0..2] [211..38]

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Predicted Domain #1
Region A:
Residues: [1-212]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSQQCVIIA IAGASASGKS LIAKTIFDEL RRDLGTDQIG VINEDAYYRD QSHLSMDERV  60
   61 LTNYDHPKAL DHQLLCTHLQ LLKSGEAVDI PCYSYTEHTR MAETVKMTPK KVIILEGILL 120
  121 LTDPKLRELM DASVFMDTPL DICFLRRLTR DVAERGRTME SVISQYKKTV RPMFLQFIEP 180
  181 SKQYADIIVP RGGKNRIATD ILKTRIQHLL AK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.0
Match: 1udwA
Description: Crystal structure of human uridine-cytidine kinase 2 complexed with a feedback-inhibitor, CTP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleobase, nucleoside, nucleotide kinase activity 3.31021342806183 bayes_pls_golite062009
nucleotide kinase activity 2.24094813695083 bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor 1.96697952975573 bayes_pls_golite062009
kinase activity 1.60827037072506 bayes_pls_golite062009
binding 1.25659194713805 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
hydrolase activity 0.420858111948277 bayes_pls_golite062009
adenylate kinase activity 0.373057703057608 bayes_pls_golite062009
nucleic acid binding 0.216266069700019 bayes_pls_golite062009

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