YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24348263, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	317 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24348263, gi|....

Description	E-value	Query Range	Subject Range
gi\|15602438, gi\|... - gi\|15602438\|ref\|NP_245510.1\| hypothetical protein PM0573 [Pasteurella multocida subsp. multocida str...	224.0	[0..1]	[317..1]
gi\|42630036 - gi\|42630036\|ref\|ZP_00155580.1\| COG0492: Thioredoxin reductase [Haemophilus influenzae R2846]	224.0	[0..1]	[317..1]
gi\|114772816 - gi\|114772816\|ref\|ZP_01450140.1\| thioredoxin reductase, FAD/NAD(P)-binding protein [alpha proteobacte... gi\|221134870 - gi\|221134870\|ref\|ZP_03561173.1\| thioredoxin reductase [Glaciecola sp. HTCC2999] gi\|114772816, gi... - gi\|114772816\|ref\|ZP_01450140.1\| thioredoxin reductase, FAD/NAD(P)-binding protein [alpha proteobacte...	224.0	[0..1]	[317..1]
gi\|46133319 - gi\|46133319\|ref\|ZP_00156998.2\| COG0492: Thioredoxin reductase [Haemophilus influenzae R2866] gi\|145639320, gi... - gi\|145639320\|ref\|ZP_01794926.1\| ferrochelatase [Haemophilus influenzae PittII], gi\|145271623\|gb\|EDK1...	224.0	[0..1]	[317..1]
gi\|77963078, gi\|... - gi\|77963078\|ref\|ZP_00826891.1\| COG0492: Thioredoxin reductase [Yersinia mollaretii ATCC 43969], gi\|2...	222.0	[0..1]	[315..1]
gi\|77958333, gi\|... - gi\|77958333\|ref\|ZP_00822368.1\| COG0492: Thioredoxin reductase [Yersinia bercovieri ATCC 43970], gi\|2...	222.0	[0..1]	[315..1]
TRXB_HAEIN - Thioredoxin reductase OS=Haemophilus influenzae GN=trxB PE=3 SV=1 TRXB_HAEIN - Thioredoxin reductase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) GN=trxB ...	221.0	[0..1]	[317..1]
gi\|37525546, gi\|... - gi\|37525546\|ref\|NP_928890.1\| thioredoxin reductase (NADPH) [Photorhabdus luminescens subsp. laumondi...	221.0	[0..1]	[315..1]
gi\|226898332, gi... - gi\|237707122\|ref\|ZP_04537603.1\| thioredoxin reductase [Escherichia sp. 3_2_53FAA], gi\|226898332\|gb\|E... gi\|26107314, gi\|... - gi\|26246914\|ref\|NP_752954.1\| thioredoxin reductase [Escherichia coli CFT073], gi\|26107314\|gb\|AAN7949... gi\|91071507, gi\|... - gi\|91209933\|ref\|YP_539919.1\| thioredoxin reductase [Escherichia coli UTI89], gi\|91071507\|gb\|ABE06388...	221.0	[0..1]	[315..41]
gi\|229689794, gi... - gi\|229843447\|ref\|ZP_04463593.1\| thioredoxin reductase, FAD/NAD(P)-binding [Yersinia pestis biovar Or... gi\|229895820, gi... - gi\|229895820\|ref\|ZP_04510990.1\| thioredoxin reductase, FAD/NAD(P)-binding [Yersinia pestis Pestoides... gi\|166009904, gi... - gi\|166009904\|ref\|ZP_02230802.1\| thioredoxin-disulfide reductase [Yersinia pestis biovar Antiqua str.... gi\|165923676, gi... - gi\|165924616\|ref\|ZP_02220448.1\| thioredoxin-disulfide reductase [Yersinia pestis biovar Orientalis s... gi\|167050633, gi... - gi\|167399925\|ref\|ZP_02305443.1\| thioredoxin-disulfide reductase [Yersinia pestis biovar Antiqua str.... gi\|166211645, gi... - gi\|166211645\|ref\|ZP_02237680.1\| thioredoxin-disulfide reductase [Yersinia pestis biovar Antiqua str.... gi\|117674145, gi... - gi\|77632358\|ref\|ZP_00794944.1\| COG0492: Thioredoxin reductase [Yersinia pseudotuberculosis IP 31758]... gi\|145599593, gi... - gi\|145599593\|ref\|YP_001163669.1\| thioredoxin reductase [Yersinia pestis Pestoides F], gi\|145211289\|g... gi\|25285000 - pir\|\|AH0167 thioredoxin-disulfide reductase (EC 1.8.1.9) [imported] - Yersinia pestis (strain CO92) gi\|45435905, gi\|... - gi\|45441046\|ref\|NP_992585.1\| thioredoxin reductase [Yersinia pestis biovar Microtus str. 91001], gi\|... gi\|21959695, gi\|... - gi\|22126679\|ref\|NP_670102.1\| thioredoxin reductase [Yersinia pestis KIM], gi\|21959695\|gb\|AAM86353.1\|... gi\|115347133, gi... - gi\|218928522\|ref\|YP_002346397.1\| thioredoxin reductase [Yersinia pestis CO92], gi\|16121654\|ref\|NP_40... Q66CK4\|Q66CK4_YERPS - Thioredoxin reductase precursor - Yersinia pseudotuberculosis gi\|51589021, gi\|... - gi\|51595739\|ref\|YP_069930.1\| thioredoxin reductase [Yersinia pseudotuberculosis IP 32953], gi\|515890... gi\|229903178, gi... - gi\|229903178\|ref\|ZP_04518291.1\| thioredoxin reductase, FAD/NAD(P)-binding [Yersinia pestis Nepal516]... gi\|167423981, gi... - gi\|167423981\|ref\|ZP_02315734.1\| thioredoxin-disulfide reductase [Yersinia pestis biovar Mediaevalis ... gi\|167419611, gi... - gi\|167419611\|ref\|ZP_02311364.1\| thioredoxin-disulfide reductase [Yersinia pestis biovar Orientalis s... gi\|186697842, gi... - gi\|186894816\|ref\|YP_001871928.1\| thioredoxin reductase [Yersinia pseudotuberculosis PB1/+], gi\|18669... gi\|170024912, gi... - gi\|170024912\|ref\|YP_001721417.1\| thioredoxin reductase [Yersinia pseudotuberculosis YPIII], gi\|16975... gi\|165913075, gi... - gi\|89105517\|ref\|ZP_01178035.1\| COG0492: Thioredoxin reductase [Yersinia pestis biovar Orientalis str... gi\|162418769, gi... - gi\|77635150\|ref\|ZP_00797238.1\| COG0492: Thioredoxin reductase [Yersinia pestis Angola], gi\|162418769... gi\|108806661, gi... - gi\|108806661\|ref\|YP_650577.1\| thioredoxin reductase [Yersinia pestis Antiqua], gi\|108778574\|gb\|ABG12... gi\|149366631, gi... - gi\|149366631\|ref\|ZP_01888665.1\| thioredoxin reductase [Yersinia pestis CA88-4125], gi\|149291005\|gb\|E... gi\|229697709, gi... - gi\|229841343\|ref\|ZP_04461502.1\| thioredoxin reductase, FAD/NAD(P)-binding [Yersinia pestis biovar Or...	221.0	[0..1]	[315..1]

Back

Predicted Domain #1

Region A:
Residues: [1-317]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQVRHSNLL ILGSGPAGYT AAVYAARANL KPVMITGMQQ GGQLTTTTEV ENWPGDAEDL  60
   61 TGPALMERMQ KHAEKFDTEI LFDHINEVTL TERPFRLKGD NGEYTCDALI IATGASARYL 120
  121 GLESEEAFKG RGVSACATCD GFFYRNQKVA VIGGGNTAVE EALYLSNIAA EVHLIHRRDT 180
  181 FRSEKILIDR LMDKVANGNI ILHLNQTMDE VVGDAMGVTG LKMKSTKDGA ITDLAVAGVF 240
  241 VAIGHSPNTG IFEGQLEMNN GYLKVQSGLQ GNATQTSIEG VFAAGDVMDQ HYRQAITSAG 300
  301 TGCMAALDAE RYLDAKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	55.69897
Match:	1tdeA
Description:	CRYSTAL STRUCTURE OF ESCHERICHIA COLI THIOREDOXIN REDUCTASE REFINED AT 2 ANGSTROM RESOLUTION: IMPLICATIONS FOR A LARGE CONFORMATIONAL CHANGE DURING CATALYSIS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
thioredoxin-disulfide reductase activity	3.42654162439464	bayes_pls_golite062009
antioxidant activity	3.37477730756688	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	3.17769237742078	bayes_pls_golite062009
catalytic activity	1.56773888754354	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor	1.45104542724719	bayes_pls_golite062009
binding	1.4227698123368	bayes_pls_golite062009
oxidoreductase activity	0.44090433301056	bayes_pls_golite062009
oxygen-dependent protoporphyrinogen oxidase activity	0.1498172520052	bayes_pls_golite062009
dihydrolipoyl dehydrogenase activity	0.130601418359425	bayes_pls_golite062009
protein binding	0.116927178396589	bayes_pls_golite062009
disulfide oxidoreductase activity	0.0160065137614933	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: