YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24348056, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	866 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24348056, gi|....

Description	E-value	Query Range	Subject Range
gi\|125972944, gi... - gi\|67875532\|ref\|ZP_00504828.1\| Iron-containing alcohol dehydrogenase [Clostridium thermocellum ATCC ...	760.0	[0..5]	[860..13]
gi\|36785819, gi\|... - gi\|37526388\|ref\|NP_929732.1\| bifunctional acetaldehyde-CoA/alcohol dehydrogenase [Photorhabdus lumin...	756.0	[0..1]	[865..1]
gi\|49611780, gi\|... - gi\|50121254\|ref\|YP_050421.1\| bifunctional acetaldehyde-CoA/alcohol dehydrogenase [Pectobacterium atr...	754.0	[0..1]	[866..1]
gi\|110802422, gi... - gi\|110802422\|ref\|YP_699787.1\| bifunctional acetaldehyde-CoA/alcohol dehydrogenase [Clostridium perfr...	752.0	[0..1]	[861..1]
gi\|117920235, gi... - gi\|78685059\|ref\|ZP_00849840.1\| aldehyde-alcohol dehydrogenase [Shewanella sp. ANA-3], gi\|78507283\|gb...	751.0	[0..1]	[866..1]
gi\|169298566, gi... - gi\|169343268\|ref\|ZP_02864279.1\| aldehyde-alcohol dehydrogenase [Clostridium perfringens C str. JGS14... gi\|18311513, gi\|... - gi\|18311513\|ref\|NP_563447.1\| bifunctional acetaldehyde-CoA/alcohol dehydrogenase [Clostridium perfri... gi\|182380321, gi... - gi\|182380321\|gb\|EDT77800.1\| aldehyde-alcohol dehydrogenase [Clostridium perfringens NCTC 8239], gi\|1... gi\|170715023, gi... - gi\|170715023\|gb\|EDT27205.1\| aldehyde-alcohol dehydrogenase [Clostridium perfringens CPE str. F4969],... gi\|170712167, gi... - gi\|170712167\|gb\|EDT24349.1\| aldehyde-alcohol dehydrogenase [Clostridium perfringens B str. ATCC 3626... gi\|170662702, gi... - gi\|170662702\|gb\|EDT15385.1\| aldehyde-alcohol dehydrogenase [Clostridium perfringens E str. JGS1987],...	750.0	[0..1]	[861..1]
gi\|110673221, gi... - gi\|110798574\|ref\|YP_697219.1\| bifunctional acetaldehyde-CoA/alcohol dehydrogenase [Clostridium perfr...	749.0	[0..1]	[861..1]
gi\|113888700, gi... - gi\|78691686\|ref\|ZP_00856288.1\| aldehyde-alcohol dehydrogenase [Shewanella sp. MR-7], gi\|78508915\|gb\|...	749.0	[0..1]	[866..1]
gi\|113970023, gi... - gi\|82496813\|ref\|ZP_00882377.1\| aldehyde-alcohol dehydrogenase [Shewanella sp. MR-4], gi\|82405222\|gb\|...	748.0	[0..1]	[866..1]
gi\|238718764, gi... - gi\|77960743\|ref\|ZP_00824601.1\| COG1012: NAD-dependent aldehyde dehydrogenases [Yersinia mollaretii A...	748.0	[0..1]	[866..1]

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Predicted Domain #1

Region A:
Residues: [1-449]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVTNAQKLD LMVERVARAQ AEYASFSQAQ VDAIFRAAAL AAADARISLA KMAAAETRMG  60
   61 VIEDKVIKNH FASEYIYNKY KDEKTCGILS EDPTFGTITI AEPVGIICGI VPTTNPTSTA 120
  121 IFKALISLKT RNAIIFSPHP RAKVSTTTAA KLVLDAAIAA GAPKDIIGWI DEPSVALSNQ 180
  181 LMTHPKVNLI LATGGPGMVK AAYSSGKPAI GVGAGNTPIV IDETADIKRA VSSILMSKTF 240
  241 DNGVVCASEQ AVIVVDSIYE QVKERFATHG GYLLNAAQTE AMQQVILKNG GLNADIVGQS 300
  301 AATIAQMAGI EVPHTTKVLI GEVTDISETE AFAHEKLSPL LGMYRAADFN DAVDKAETLV 360
  361 ALGGIGHTSG LYTDQDTQTE RVKSFGFRMK TARILINTPA SQGGIGDLYN FKLAPSLTLG 420
  421 CGSWGGNSIS ENVGPSHLIN KKTVAKRAE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	132.0
Match:	1bxsA
Description:	Aldehyde reductase (dehydrogenase), ALDH
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity	4.47226217021998	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	4.34495776828926	bayes_pls_golite062009
3-chloroallyl aldehyde dehydrogenase activity	3.37049090049734	bayes_pls_golite062009
succinate-semialdehyde dehydrogenase [NAD(P)+] activity	3.30681232755737	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	3.2867555127991	bayes_pls_golite062009
aldehyde dehydrogenase (NAD) activity	2.81851373615334	bayes_pls_golite062009
catalytic activity	2.80804701752928	bayes_pls_golite062009
succinate-semialdehyde dehydrogenase activity	2.25908515251731	bayes_pls_golite062009
benzaldehyde dehydrogenase activity	1.80313175632526	bayes_pls_golite062009
methylmalonate-semialdehyde dehydrogenase (acylating) activity	1.59279206536309	bayes_pls_golite062009
1-pyrroline-5-carboxylate dehydrogenase activity	1.15620590715864	bayes_pls_golite062009
binding	0.637403449596354	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [450-866]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NMLWHKLPSS IYFRRGSLPI ALEELSDKKR ALIVTDPFLF NQGYCDETLK ILKAQGLETE  60
   61 VFYEVEADPT LATVRQGAKV ANSFKPDVII ALGGGSPMDA AKIIWVMYEH PDVDFADLAL 120
  121 RFMDIRKRIY KFPKMGVKAT MVAIPTTSGT GSEVTPFAVV TDEQTGKKYP IADYQLTPNM 180
  181 AIVDPNLVMD MPKSLTAFGG IDAITHALEA YVSVMANEYS DGQALQALDL LCKYLPDAYQ 240
  241 LGAASPIARE KVHNGATIAG IAFANAFLGI CHSMAHKLGA EFHLAHGLAN ALLISNVIRF 300
  301 NATDLPTKQA AFSQYDRPKA LCRYAAIADH LALGGNSDAQ KVEKLLEKIE QLKKTLGIPA 360
  361 SIQEAGVNEA DFLAKLDMLA EDAFDDQCTG ANPRYPLISE LKQLLLDSYY GRPFTEQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	91.69897
Match:	1rrmA
Description:	Crystal Structure of Lactaldehyde reductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
alcohol dehydrogenase (NAD) activity	5.26400058766942	bayes_pls_golite062009
oxidoreductase activity	3.07409531087588	bayes_pls_golite062009
alcohol dehydrogenase activity, metal ion-independent	3.05722501802075	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	2.83823088483915	bayes_pls_golite062009
catalytic activity	2.37357608468991	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2.10085302216488	bayes_pls_golite062009
binding	1.15096180564234	bayes_pls_golite062009
3-chloroallyl aldehyde dehydrogenase activity	0.831155115586418	bayes_pls_golite062009
cation binding	0.319000821544479	bayes_pls_golite062009
metal ion binding	0.319000821544479	bayes_pls_golite062009
ion binding	0.313606245452103	bayes_pls_golite062009
protein binding	0.295023706645045	bayes_pls_golite062009
transition metal ion binding	0.259889634539407	bayes_pls_golite062009
hydroxyacid-oxoacid transhydrogenase activity	0.146499147589879	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	0.0904828025133766	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: