YRC Public Data Repository - Protein Structure Prediction

Protein:	TILS_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	464 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TILS_SHEON.

Description	E-value	Query Range	Subject Range
gi\|30039987, gi\|... - gi\|30061745\|ref\|NP_835916.1\| tRNA(Ile)-lysidine synthetase [Shigella flexneri 2a str. 2457T], gi\|300...	315.0	[0..19]	[455..9]
gi\|75240223, gi\|... - gi\|75240223\|ref\|ZP_00724170.1\| COG0037: Predicted ATPase of the PP-loop superfamily implicated in ce... gi\|110341999, gi... - gi\|110640407\|ref\|YP_668135.1\| tRNA(Ile)-lysidine synthetase [Escherichia coli 536], gi\|110341999\|gb\|...	315.0	[0..19]	[455..9]
gi\|227884899, gi... - gi\|227884899\|ref\|ZP_04002704.1\| PP-loop superfamily ATPase [Escherichia coli 83972], gi\|227838037\|gb... TILS_ECOL6 - tRNA(Ile)-lysidine synthase OS=Escherichia coli O6 GN=tilS PE=3 SV=1 TILS_ECOL6 - tRNA(Ile)-lysidine synthase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=tilS P...	315.0	[0..19]	[455..9]
gi\|75258821, gi\|... - gi\|75258821\|ref\|ZP_00730211.1\| COG0037: Predicted ATPase of the PP-loop superfamily implicated in ce... gi\|192959000, gi... - gi\|75238891\|ref\|ZP_00722873.1\| COG0037: Predicted ATPase of the PP-loop superfamily implicated in ce... gi\|75210511, gi\|... - gi\|75210511\|ref\|ZP_00710662.1\| COG0037: Predicted ATPase of the PP-loop superfamily implicated in ce... gi\|157158325, gi... - gi\|75189283\|ref\|ZP_00702550.1\| COG0037: Predicted ATPase of the PP-loop superfamily implicated in ce...	315.0	[0..19]	[455..9]
TILS_SHIFL - tRNA(Ile)-lysidine synthase OS=Shigella flexneri GN=tilS PE=3 SV=2 gi\|24111623, gi\|... - gi\|24111623\|ref\|NP_706133.1\| tRNA(Ile)-lysidine synthetase [Shigella flexneri 2a str. 301], gi\|24050...	315.0	[0..19]	[455..9]
gi\|73854286, gi\|... - gi\|74310809\|ref\|YP_309228.1\| tRNA(Ile)-lysidine synthetase [Shigella sonnei Ss046], gi\|73854286\|gb\|A...	315.0	[0..19]	[455..9]
gi\|187730131, gi... - gi\|75176467\|ref\|ZP_00696604.1\| COG0037: Predicted ATPase of the PP-loop superfamily implicated in ce... gi\|82542786, gi\|... - gi\|82542786\|ref\|YP_406733.1\| tRNA(Ile)-lysidine synthetase [Shigella boydii Sb227], gi\|81244197\|gb\|A...	315.0	[0..19]	[455..9]
gi\|188492707, gi... - gi\|75512200\|ref\|ZP_00734772.1\| COG0037: Predicted ATPase of the PP-loop superfamily implicated in ce... gi\|226840713, gi... - gi\|254037607\|ref\|ZP_04871684.1\| tRNA(Ile)-lysidine synthetase [Escherichia sp. 1_1_43], gi\|226840713...	314.0	[0..19]	[455..9]
gi\|190902916, gi... - gi\|75229828\|ref\|ZP_00716355.1\| COG0037: Predicted ATPase of the PP-loop superfamily implicated in ce...	314.0	[0..19]	[455..9]
gi\|209910637, gi... - gi\|209917378\|ref\|YP_002291462.1\| tRNA(Ile)-lysidine synthetase [Escherichia coli SE11], gi\|209910637... gi\|157159653, gi... - gi\|75194398\|ref\|ZP_00704468.1\| COG0037: Predicted ATPase of the PP-loop superfamily implicated in ce... gi\|218552769, gi... - gi\|218552769\|ref\|YP_002385682.1\| tRNA(Ile)-lysidine synthetase [Escherichia coli IAI1], gi\|218359537... gi\|218350385, gi... - gi\|218693653\|ref\|YP_002401320.1\| tRNA(Ile)-lysidine synthetase [Escherichia coli 55989], gi\|21835038...	314.0	[0..19]	[455..9]

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Predicted Domain #1

Region A:
Residues: [1-464]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAQDLSVHI ARWLDSLPLQ AGSKLVLAYS GGVDSEVLAY GLSEYAKQRP DLRYQLIYVH  60
   61 HGLSPNADNW AKHCQARAAI YGLPVTVERV QLILGPRVSV EAEARKARYQ AILPHLNPQD 120
  121 ILLTAHHEDD QLETILLALK RGQGPKGLAA MGQIQPLSLA DKGSCLQVRP LLDISREMIE 180
  181 TFAQTRQLVH IEDESNQDDK YDRNFLRLEI IPRLKARWPS IATTASRSAQ LCAEQQAIVE 240
  241 TEVSERLPKL LVKAPVTEQT VLKLSELAAQ PIEWQGILLR GFIESQEFSL PSYVQLQQML 300
  301 QQLIHAKEDA KVHIRINDCV LRRFAGMLYL DSGETLSTAL HITARDLHQE ILTLLTQASA 360
  361 MVEDKIVPFA LVTTGPRLRL PKADEVVSLG YGLPGQFRCQ PHFRDKGREL KKLWQECAVP 420
  421 PWLRAEVGFL FYNDKLVMAF GLWVEKAFCA QGDEIGLSYL IANP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	84.30103
Match:	1ni5A
Description:	Putative cell cycle protein MesJ, N-terminal domain; Putative cell cycle protein MesJ, middle and C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming carbon-oxygen bonds	4.62261539719166	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	4.62261539719166	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	4.6196700624078	bayes_pls_golite062009
phenylalanine-tRNA ligase activity	3.61307332554234	bayes_pls_golite062009
ligase activity	3.26222666347152	bayes_pls_golite062009
catalytic activity	1.19930793139888	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	0.196167461233561	bayes_pls_golite062009
carbon-nitrogen ligase activity, with glutamine as amido-N-donor	0.137409332385789	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: