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View Structure Prediction Details

Protein: gi|24372856, gi|...
Organism: Shewanella oneidensis MR-1
Length: 482 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24372856, gi|....

Description E-value Query
Range
Subject
Range
gi|45523555, gi|... - gi|67925207|ref|ZP_00518574.1| Aldehyde dehydrogenase (NAD+) [Crocosphaera watsonii WH 8501], gi|678...
633.0 [0..10] [482..15]
AL1A1_SHEEP - Retinal dehydrogenase 1 OS=Ovis aries GN=ALDH1A1 PE=1 SV=2
629.0 [0..3] [482..13]
AL1A1_BOVIN - Retinal dehydrogenase 1 OS=Bos taurus GN=ALDH1A1 PE=2 SV=3
628.0 [0..3] [482..13]
AL1A1_CHICK - Retinal dehydrogenase 1 OS=Gallus gallus GN=ALDH1A1 PE=2 SV=1
627.0 [0..3] [482..21]
gi|52785994, gi|... - gi|52785994|ref|YP_091823.1| DhaS [Bacillus licheniformis ATCC 14580], gi|52348496|gb|AAU41130.1| Dh...
627.0 [0..12] [480..24]
gi|56961829, gi|... - gi|56961829|ref|YP_173551.1| aldehyde dehydrogenase [Bacillus clausii KSM-K16], gi|56908063|dbj|BAD6...
627.0 [0..12] [482..25]
gi|60653829, gi|... - gi|60653831|gb|AAX29608.1| aldehyde dehydrogenase 1 family member A1 [synthetic construct], gi|60653...
626.0 [0..3] [482..13]
gi|123979532, gi... - gi|61362025|gb|AAX42143.1| aldehyde dehydrogenase 1 family member A1 [synthetic construct], gi|61362...
ALDH1A1 - aldehyde dehydrogenase 1 family, member A1
gi|114625008, gi... - gi|114625014|ref|XP_001143446.1| PREDICTED: aldehyde dehydrogenase 1A1 isoform 9 [Pan troglodytes], ...
626.0 [0..3] [482..13]

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Predicted Domain #1
Region A:
Residues: [1-482]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLNDPSLLR QQCYINGQWC DANSKETVAI TNPATGAVIA CVPVMGQAET QAAIAAAEAA  60
   61 LPAWRALTAK ERGAKLRRWF ELLNENSDDL ALLMTSEQGK PLTEAKGEVT YAASFIEWFA 120
  121 EEAKRIYGDT IPGHQGDKRI MVIKQPVGVT AAITPWNFPA AMITRKAAPA LAAGCTMVVK 180
  181 PAPQTPFTAL ALAVLAERAG IPAGVFSVIT GDAIAIGNEM CTNPIVRKLS FTGSTNVGIK 240
  241 LMAQCAPTLK KLSLELGGNA PFIVFDDANI DAAVEGAMIA KYRNAGQTCV CANRIYVQAG 300
  301 VYDEFAEKLS MAVAKLKVGE GIIAGVTTGP LINAAAVEKV QSHLEDAIKK GATVLAGGKV 360
  361 HELGGNFFEP TVLTNADKSM RVAREETFGP LAPLFKFNDV DDVIKQANDT EFGLAAYFYG 420
  421 RDISLVWKVA ESLEYGMVGV NTGLISTEVA PFGGMKSSGL GREGSKYGIE EYLEIKYICM 480
  481 SV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 1bxsA
Description: Aldehyde reductase (dehydrogenase), ALDH
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on the aldehyde or oxo group of donors 5.09598561374689 bayes_pls_golite062009
oxidoreductase activity 4.47226217021998 bayes_pls_golite062009
malonate-semialdehyde dehydrogenase (acetylating) activity 4.2273960318884 bayes_pls_golite062009
methylmalonate-semialdehyde dehydrogenase (acylating) activity 3.87605237828483 bayes_pls_golite062009
succinate-semialdehyde dehydrogenase [NAD(P)+] activity 3.64672165191647 bayes_pls_golite062009
1-pyrroline-5-carboxylate dehydrogenase activity 3.49281413016612 bayes_pls_golite062009
3-chloroallyl aldehyde dehydrogenase activity 3.37049090049734 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3.2867555127991 bayes_pls_golite062009
benzaldehyde dehydrogenase activity 2.99564252244797 bayes_pls_golite062009
aldehyde dehydrogenase (NAD) activity 2.81851373615334 bayes_pls_golite062009
catalytic activity 2.80804701752928 bayes_pls_golite062009
succinate-semialdehyde dehydrogenase activity 2.71501590413507 bayes_pls_golite062009
aldehyde dehydrogenase [NAD(P)+] activity 2.43250909158896 bayes_pls_golite062009
aminobutyraldehyde dehydrogenase activity 2.35958138496479 bayes_pls_golite062009
acyl-CoA binding 2.26220696569489 bayes_pls_golite062009
retinal dehydrogenase activity 1.42867174920845 bayes_pls_golite062009
binding 1.06673666884196 bayes_pls_golite062009
retinoid binding 0.983782635681687 bayes_pls_golite062009
isoprenoid binding 0.900374761028287 bayes_pls_golite062009
protein binding 0.894945263794726 bayes_pls_golite062009
glutamate-5-semialdehyde dehydrogenase activity 0.882678635212924 bayes_pls_golite062009
histidinol dehydrogenase activity 0.258030369394064 bayes_pls_golite062009
benzaldehyde dehydrogenase (NAD+) activity 0.23487570676521 bayes_pls_golite062009

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