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View Structure Prediction Details

Protein: PROA_SHEON
Organism: Shewanella oneidensis MR-1
Length: 425 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PROA_SHEON.

Description E-value Query
Range
Subject
Range
gi|20372798 - gi|20372798|emb|CAD30313.1| aldehyde dehydrogenase [Geobacillus stearothermophilus]
418.0 [0..1] [418..48]
gi|52785994, gi|... - gi|52785994|ref|YP_091823.1| DhaS [Bacillus licheniformis ATCC 14580], gi|52348496|gb|AAU41130.1| Dh...
417.0 [0..5] [421..57]
gi|56684572, gi|... - gi|56684572|gb|AAW21985.1| RALDH3 [Xenopus laevis], gi|213626544|gb|AAI69603.1| RALDH3 [Xenopus laev...
416.0 [0..5] [422..66]
gi|45382777, gi|... - gi|45382777|ref|NP_990000.1| aldehyde dehydrogenase 1A3 [Gallus gallus], gi|11596123|gb|AAG38487.1| ...
415.0 [0..5] [422..66]
AL1A3_RAT - Aldehyde dehydrogenase family 1 member A3 OS=Rattus norvegicus GN=Aldh1a3 PE=2 SV=1
414.0 [0..5] [419..66]
AL1A1_RABIT - Retinal dehydrogenase 1 OS=Oryctolagus cuniculus GN=ALDH1A1 PE=2 SV=1
414.0 [0..5] [422..50]
AL1A1_SHEEP - Retinal dehydrogenase 1 OS=Ovis aries GN=ALDH1A1 PE=1 SV=2
414.0 [0..5] [422..55]
AL1A1_BOVIN - Retinal dehydrogenase 1 OS=Bos taurus GN=ALDH1A1 PE=2 SV=3
413.0 [0..5] [422..55]
AL1A3_MOUSE - Aldehyde dehydrogenase family 1 member A3 OS=Mus musculus GN=Aldh1a3 PE=1 SV=1
413.0 [0..5] [419..66]

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Predicted Domain #1
Region A:
Residues: [1-425]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQINQAQYL QQLGHNAKQA SYALANLTAS QKADLLDAIA DALTENTLAI LAANAKDVAA  60
   61 AKAEGLNDAM IDRLLLNESR LAGIIGDISD VVRLADPVGE EFGSRVLDNG LRLTRRRVPL 120
  121 GVIGVIYEAR PNVTVDIAVL ALKTGNAVIL RGGKETLESN KLISEVIRGA IASQGLPVDA 180
  181 VQLIDSSDRA LVTGLLKLDQ YVDMIVPRGG QALQRLCAEQ ATIPVILGGI GICHLYVDKA 240
  241 ANLERALEVI ANAKVQRPTV CNALDTLLVD KTIAANFVPQ IVEYLHCLGV RFSVCEQSHA 300
  301 LLDGLGFDIE LATEQSFATE WLSLTLGIKV VSDIDAAIAH IRRHSSGHSE AILTDDIHAA 360
  361 THFMNEVNSA AVYVNASTRF TDGGQFGLGA EVAVSTQKLH ARGPMGLEAL TTYKWLAWGD 420
  421 YTSRA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 84.69897
Match: 1o20A
Description: Gamma-glutamyl phosphate reductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glutamate-5-semialdehyde dehydrogenase activity 3.27180265380824 bayes_pls_golite062009
catalytic activity 2.80804701752928 bayes_pls_golite062009
oxidoreductase activity 2.31275077585879 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 2.24875477727877 bayes_pls_golite062009
1-pyrroline-5-carboxylate dehydrogenase activity 2.23071641559385 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2.22720948878196 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1.6559690223037 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors 1.40606039383065 bayes_pls_golite062009
binding 1.06673666884196 bayes_pls_golite062009
histidinol dehydrogenase activity 0.258030369394064 bayes_pls_golite062009

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