YRC Public Data Repository - Protein Structure Prediction

Protein:	GCST_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	364 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GCST_SHEON.

Description	E-value	Query Range	Subject Range
GCST_SHESM - Aminomethyltransferase OS=Shewanella sp. (strain MR-4) GN=gcvT PE=3 SV=1	438.0	[0..1]	[364..1]
GCST_SHESA - Aminomethyltransferase OS=Shewanella sp. (strain ANA-3) GN=gcvT PE=3 SV=1	438.0	[0..1]	[364..1]
GCST_SHESW - Aminomethyltransferase OS=Shewanella sp. (strain W3-18-1) GN=gcvT PE=3 SV=1 GCST_SHEPC - Aminomethyltransferase OS=Shewanella putrefaciens (strain CN-32 / ATCC BAA-453) GN=gcvT PE=3 SV=1	437.0	[0..1]	[364..1]
GCST_SHESR - Aminomethyltransferase OS=Shewanella sp. (strain MR-7) GN=gcvT PE=3 SV=1	436.0	[0..1]	[364..1]
gi\|149289490, gi... - gi\|150260082\|ref\|ZP_01916810.1\| aminomethyltransferase [Yersinia pestis CA88-4125], gi\|149289490\|gb\|... GCST_YERPP - Aminomethyltransferase OS=Yersinia pestis (strain Pestoides F) GN=gcvT PE=3 SV=1 GCST_YERPE - Aminomethyltransferase OS=Yersinia pestis GN=gcvT PE=3 SV=1 gi\|21960233, gi\|... - gi\|22127170\|ref\|NP_670593.1\| glycine cleavage system aminomethyltransferase T [Yersinia pestis KIM],... gi\|115346691, gi... - gi\|218928080\|ref\|YP_002345955.1\| glycine cleavage system aminomethyltransferase T [Yersinia pestis C... gi\|45443338, gi\|... - gi\|45443338\|ref\|NP_994877.1\| glycine cleavage system aminomethyltransferase T [Yersinia pestis biova... gi\|229837595, gi... - gi\|229837595\|ref\|ZP_04457757.1\| aminomethyltransferase, tetrahydrofolate-dependent, subunit (T prote... gi\|229840819, gi... - gi\|229840819\|ref\|ZP_04460978.1\| aminomethyltransferase, tetrahydrofolate-dependent, subunit (T prote... gi\|229842622, gi... - gi\|229842622\|ref\|ZP_04462777.1\| aminomethyltransferase, tetrahydrofolate-dependent, subunit (T prote... GCST_YERPB - Aminomethyltransferase OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN=gcvT PE=3 SV=1 gi\|165914681, gi... - gi\|89102642\|ref\|ZP_01175260.1\| COG0404: Glycine cleavage system T protein (aminomethyltransferase) [... gi\|165923172, gi... - gi\|165924972\|ref\|ZP_02220804.1\| glycine cleavage system T protein [Yersinia pestis biovar Orientalis... GCST_YERPA - Aminomethyltransferase OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=gcvT PE=3 SV=1 GCST_YERPN - Aminomethyltransferase OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=gcvT PE=3 SV=1 gi\|166205998, gi... - gi\|166212706\|ref\|ZP_02238741.1\| glycine cleavage system T protein [Yersinia pestis biovar Antiqua st... gi\|165990820, gi... - gi\|166010334\|ref\|ZP_02231232.1\| glycine cleavage system T protein [Yersinia pestis biovar Antiqua st... gi\|167419345, gi... - gi\|167419345\|ref\|ZP_02311098.1\| glycine cleavage system T protein [Yersinia pestis biovar Orientalis... gi\|167399824, gi... - gi\|167399824\|ref\|ZP_02305342.1\| glycine cleavage system T protein [Yersinia pestis biovar Antiqua st... gi\|167467675 - gi\|167467675\|ref\|ZP_02332379.1\| glycine cleavage system T protein [Yersinia pestis FV-1] GCST_YERPG - Aminomethyltransferase OS=Yersinia pestis bv. Antiqua (strain Angola) GN=gcvT PE=3 SV=1 gi\|167055699, gi... - gi\|167425299\|ref\|ZP_02317052.1\| glycine cleavage system T protein [Yersinia pestis biovar Mediaevali...	435.0	[0..1]	[361..1]
GCST_SHEAM - Aminomethyltransferase OS=Shewanella amazonensis (strain ATCC BAA-1098 / SB2B) GN=gcvT PE=3 SV=1	435.0	[0..1]	[364..1]
gi\|75239248 - gi\|75239248\|ref\|ZP_00723221.1\| COG0404: Glycine cleavage system T protein (aminomethyltransferase) [... gi\|117625135, gi... - gi\|117625135\|ref\|YP_854123.1\| glycine cleavage system aminomethyltransferase T [Escherichia coli APE... gi\|110344645, gi... - gi\|110643053\|ref\|YP_670783.1\| glycine cleavage system aminomethyltransferase T [Escherichia coli 536...	435.0	[0..1]	[361..24]
GCST_YERPS - Aminomethyltransferase OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=gcvT PE=3 SV=1 GCST_YERPS - Aminomethyltransferase OS=Yersinia pseudotuberculosis GN=gcvT PE=3 SV=1 GCST_YERP3 - Aminomethyltransferase OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=gcvT PE=3 S...	434.0	[0..1]	[361..1]
GCST_SHEB9 - Aminomethyltransferase OS=Shewanella baltica (strain OS195) GN=gcvT PE=3 SV=1	434.0	[0..1]	[364..1]
GCST_SHEB5 - Aminomethyltransferase OS=Shewanella baltica (strain OS155 / ATCC BAA-1091) GN=gcvT PE=3 SV=1	434.0	[0..1]	[364..1]

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Predicted Domain #1

Region A:
Residues: [1-364]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANKTVLFNK HLESNAKMVD FHGWDMPLNY GSQIEEHHAV RQDAGMFDVS HMTVVDVTGT  60
   61 DACAFLRKLL ANDVAKLKVP GKALYGGMLD DNAGIIDDLI TYYLTDTFYR VVVNSATREK 120
  121 DLAWIAKQSQ GFDVTVTERP ELAMIAVQGP NAKAKAAAVF SSEQNAAIEG MKPFFGKQAG 180
  181 SLFIATTGYT GEAGYEIIVP ETEAEALWQA LLDQGVKPCG LGARDTLRLE AGMNLYGLDM 240
  241 DETINPLAAN MGWTIAWEPT DRDFIGRKAL EALRDAGTDK LVGLVMEEKG VLRHDMPVFF 300
  301 TDAAGVEQQG VITSGTFSPT LGYSIAMARV PSSIGDTAEV EMRKKRVAVR VVAPNFVRNG 360
  361 KQAF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	120.0
Match:	1vloA
Description:	Crystal structure of aminomethyltransferase (T protein; tetrahydrofolate-dependent) of glycine cleavage system (np417381) from Escherichia coli k12 at 1.70 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
aminomethyltransferase activity	10.5654741349554	bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity	5.37200252580633	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	5.37200252580633	bayes_pls_golite062009
methyltransferase activity	3.28983380541263	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	3.20782575104451	bayes_pls_golite062009
catalytic activity	1.65079399897053	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors	1.19783690850993	bayes_pls_golite062009
oxidoreductase activity	0.867567984371732	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors	0.550291785460228	bayes_pls_golite062009
transferase activity	0.217873555384951	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: