YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24372339, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	496 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24372339, gi|....

Description	E-value	Query Range	Subject Range
gi\|110640141, gi... - gi\|110640141\|ref\|YP_680351.1\| glutamate synthase (NADH) large subunit [Cytophaga hutchinsonii ATCC 3... gi\|48854264 - gi\|48854264\|ref\|ZP_00308427.1\| COG0069: Glutamate synthase domain 2 [Cytophaga hutchinsonii]	383.0	[0..13]	[494..763]
gi\|66576244 - gi\|66576244\|gb\|AAM71647.2\| glutamate synthase, large subunit [Chlorobium tepidum TLS]	382.0	[0..12]	[494..766]
gi\|88779892, gi\|... - gi\|88797023\|ref\|ZP_01112613.1\| glutamate synthase, large subunit, GOGAT [Reinekea sp. MED297], gi\|88...	375.0	[0..13]	[494..765]
gi\|1339950 - gi\|1339950\|dbj\|BAA12741.1\| large subunit of NADH-dependent glutamate synthase [Leptolyngbya boryana] gi\|1339950\|dbj\|B... - large subunit of NADH-dependent glutamate synthase [Leptolyngbya boryana]	372.0	[0..13]	[494..761]
gi\|68240737, gi\|... - gi\|68552392\|ref\|ZP_00591782.1\| Glutamate synthase (NADPH) [Prosthecochloris aestuarii DSM 271], gi\|6...	372.0	[0..13]	[494..717]
gi\|15894950, gi\|... - gi\|15894950\|ref\|NP_348299.1\| large subunit of NADH-dependent glutamate synthase [Clostridium acetobu... gi\|25284760 - pir\|\|D97106 large chain of NADH-dependent glutamate synthase CAC1673 [imported] - Clostridium acetob...	372.0	[0..13]	[494..761]
gi\|49646984 - gi\|49646984\|emb\|CAG83371.1\| YALI0B19998p [Yarrowia lipolytica] gi\|50547297, gi\|... - gi\|50547297\|ref\|XP_501118.1\| YALI0B19998p [Yarrowia lipolytica], gi\|49646984\|emb\|CAG83371.1\| unnamed...	370.0	[0..13]	[495..802]
gi\|110597773, gi... - gi\|110597773\|ref\|ZP_01386057.1\| Glutamate synthase (ferredoxin) [Chlorobium ferrooxidans DSM 13031],...	370.0	[0..13]	[491..762]
gi\|67783109, gi\|... - gi\|67919271\|ref\|ZP_00512854.1\| Glutamate synthase (NADPH) [Chlorobium limicola DSM 245], gi\|67783109...	368.0	[0..13]	[494..762]

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Predicted Domain #1

Region A:
Residues: [1-496]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHELNWFMWG LDLFSGLFLI IVGLGALAIV YMYIADKLQT KQAVRHNYPV IGRFRYLFEK  60
   61 QGEFFRQYFF AQDREELPFN RAERSWVYRA AKNVDRTIAF GSTRPLEATG TIMFMNSAFP 120
  121 PQDEDITPIQ PLTIGPHCRV PYTTSAICHI SAMSFGALSR PAVTALSHGA AQAGCWLNTG 180
  181 EGGLSPYHLK GGCDLVFQIG TAKYGVRNEH GHLDDDKLTA IAAHPEVKMF EIKMSQGAKP 240
  241 GKGGILPGVK VTEEIAHIRG IPLGQDSISP NGHIEFNNVG DILDMIARVR EVTGKPTGIK 300
  301 AVLGDVQWLE DFCNEIERRG EASAPDFFTL DSADGGTGAA PQPLMDYVGL PLKESLPILV 360
  361 NILIKHGLGK RIKVIASGKL IVPSRVAWAL ALGADFIASA RGNMFALGCI QALQCNKDTC 420
  421 PTGITTHNKK LQHGLDPRDK STRVANYNHN LHHDLALIAH SCGLTEPRQL KPSHVRIVLE 480
  481 SGLSVSLDKY YSHINN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	93.30103
Match:	1llwA
Description:	Alpha subunit of glutamate synthase, C-terminal domain; Alpha subunit of glutamate synthase, central and FMN domains; Alpha subunit of glutamate synthase, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glutamate synthase activity	3.91479938731359	bayes_pls_golite062009
glutamate synthase activity, NADH or NADPH as acceptor	3.11497451731556	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	2.64105846956746	bayes_pls_golite062009
glutamate synthase (NADPH) activity	2.48164352509862	bayes_pls_golite062009
oxidoreductase activity	2.15666801512485	bayes_pls_golite062009
catalytic activity	1.94749091175302	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	0.330721070169443	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: